Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Thomas P Brouwer"'
Autor:
Zheng Li, Frits Koning, Natasja L de Vries, Tamim Abdelaal, Boudewijn P F Lelieveldt, Noel F C C de Miranda, Hans Morreau, Dina Ruano, Alexander L Vahrmeijer, Bert A Bonsing, Thomas P Brouwer, Ricki T Krog, Arantza Fariña
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy in need of effective (immuno)therapeutic treatment strategies. For the optimal application and development of cancer immunotherapies, a comprehensive understanding of lo
Externí odkaz:
https://doaj.org/article/13685e07570f4ae2a64498103c5f4c6c
Autor:
Giulia Trimaglio, Tamara Sneperger, Benjamin B. A. Raymond, Nelly Gilles, Emmanuelle Näser, Marie Locard-Paulet, Marieke E. Ijsselsteijn, Thomas P. Brouwer, Romain Ecalard, Jessica Roelands, Naoki Matsumoto, André Colom, Myriam Habch, Noel F. C. C. de Miranda, Nathalie Vergnolle, Christel Devaud, Olivier Neyrolles, Yoann Rombouts
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Development and progression of malignancies are accompanied and influenced by alterations in the surrounding immune microenvironment. Understanding the cellular and molecular interactions between immune cells and cancer cells has not only pr
Externí odkaz:
https://doaj.org/article/f3225b2dcc7a4c39953c371ada897c96
Autor:
Francesca Finotello, Clemens Mayer, Christina Plattner, Gerhard Laschober, Dietmar Rieder, Hubert Hackl, Anne Krogsdam, Zuzana Loncova, Wilfried Posch, Doris Wilflingseder, Sieghart Sopper, Marieke Ijsselsteijn, Thomas P. Brouwer, Douglas Johnson, Yaomin Xu, Yu Wang, Melinda E. Sanders, Monica V. Estrada, Paula Ericsson-Gonzalez, Pornpimol Charoentong, Justin Balko, Noel Filipe da Cunha Carvalho de Miranda, Zlatko Trajanoski
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-20 (2019)
Abstract We introduce quanTIseq, a method to quantify the fractions of ten immune cell types from bulk RNA-sequencing data. quanTIseq was extensively validated in blood and tumor samples using simulated, flow cytometry, and immunohistochemistry data.
Externí odkaz:
https://doaj.org/article/efe12b1b010b4124877e3449d722878c
Autor:
Francesca Finotello, Clemens Mayer, Christina Plattner, Gerhard Laschober, Dietmar Rieder, Hubert Hackl, Anne Krogsdam, Zuzana Loncova, Wilfried Posch, Doris Wilflingseder, Sieghart Sopper, Marieke Ijsselsteijn, Thomas P. Brouwer, Douglas Johnson, Yaomin Xu, Yu Wang, Melinda E. Sanders, Monica V. Estrada, Paula Ericsson-Gonzalez, Pornpimol Charoentong, Justin Balko, Noel Filipe da Cunha Carvalho de Miranda, Zlatko Trajanoski
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-3 (2019)
It was highlighted that the original article [1] contained a typesetting mistake in the name of Noel Filipe da Cunha Carvalho de Miranda. This was incorrectly captured as Noel Filipe da Cunha Carvahlo de Miranda. It was also highlighted that in Fig.
Externí odkaz:
https://doaj.org/article/ac397ecee0e54e62977223686bd82fd0
Autor:
Thomas P. Brouwer, Sabina Y. van der Zanden, Manon van der Ploeg, Jaap D.H. van Eendenburg, Bert A. Bonsing, Noel F.C.C. de Miranda, Jacques J. Neefjes, Alexander L. Vahrmeijer
Publikováno v:
Anti-Cancer Drugs, 33(7), 614-621. LIPPINCOTT WILLIAMS & WILKINS
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of cancer, mainly due to its delayed diagnosis and lack of effective therapeutic options. Therefore, it is imperative to find novel treatment options for PDAC. Here, we tested a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff95a2e6ff18107eba6980054272581
https://hdl.handle.net/1887/3563421
https://hdl.handle.net/1887/3563421
Publikováno v:
Cellular Oncology (Dordrecht)
Cellular Oncology
Cellular Oncology, 44(2), 261-278. SPRINGER
Cellular Oncology
Cellular Oncology, 44(2), 261-278. SPRINGER
BackgroundCheckpoint blockade immunotherapy has had a significant impact on the survival of a subset of patients with advanced cancers. It has been particularly effective in immunogenic cancer types that present large numbers of somatic mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ba56a454d09e2fe6333b90e751e863
https://pubmed.ncbi.nlm.nih.gov/33710604
https://pubmed.ncbi.nlm.nih.gov/33710604
Autor:
Noel F C C de Miranda, Bert A. Bonsing, Thomas P. Brouwer, Jaap Dh van Eendenburg, Jacques Neefjes, Alexander L. Vahrmeijer, Sabina Y van der Zanden
BackgroundPancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of cancer, mainly due to its delayed diagnosis and lack of effective therapeutic options. Therefore, it is imperative to find novel treatment options for PDAC. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd936fd8d805f844845f3de25c4a36fb
https://doi.org/10.21203/rs.3.rs-78195/v1
https://doi.org/10.21203/rs.3.rs-78195/v1
Cancer immunophenotyping by seven-colour multispectral imaging without tyramide signal amplification
Autor:
Noel F C C de Miranda, Marieke E. Ijsselsteijn, Alexander L. Vahrmeijer, Ziena Abdulrahman, A. Marijne Heeren, Ekaterina S. Jordanova, Ana Ramalheiro, Thomas P. Brouwer, Eileen Reidy
Publikováno v:
The Journal of Pathology: Clinical Research. 5:3-11
Checkpoint blockade immunotherapies have revolutionised cancer treatment in the last decade. Nevertheless, these are only beneficial for a small proportion of cancer patients. Important prognosticators for response to immunotherapy are the mutation b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38c2309d48835d4c1703a280f6407380
https://doi.org/10.1002/cjp2.113
https://doi.org/10.1002/cjp2.113
Autor:
Anne Krogsdam, Francesca Finotello, Clemens Mayer, Marieke E. Ijsselsteijn, Thomas P. Brouwer, Wilfried Posch, Melinda E. Sanders, Justin M. Balko, Sieghart Sopper, Yu Wang, Noel Filipe da Cunha Carvalho de Miranda, Douglas B. Johnson, Pornpimol Charoentong, Doris Wilflingseder, Yaomin Xu, Monica V. Estrada, Zlatko Trajanoski, Christina Plattner, Dietmar Rieder, Paula I. Ericsson-Gonzalez, Hubert Hackl, Gerhard Laschober, Zuzana Loncova
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-3 (2019)
It was highlighted that the original article [1] contained a typesetting mistake in the name of Noel Filipe da Cunha Carvalho de Miranda. This was incorrectly captured as Noel Filipe da Cunha Carvahlo de Miranda. It was also highlighted that in Fig.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e7de30b455a6654cd53a395005352a
http://link.springer.com/article/10.1186/s13073-019-0655-5
http://link.springer.com/article/10.1186/s13073-019-0655-5
Autor:
Sebastian Diecke, Thomas P. Brouwer, Idit Sagiv-Barfi, Paul H.A. Quax, Raman Nelakanti, Youngkyun Kim, Arnold Han, Devaveena Dey, Tzu-Tang Wei, Ning-Yi Shao, Joseph C. Wu, Jaap F. Hamming, Nigel G. Kooreman, Vittavat Termglinchan, Ronald Levy, Patrícia de Almeida, David T. Paik, Mark M. Davis, Hyoju Yi
Publikováno v:
Cell Stem Cell, 22(4), 501
Summary Cancer cells and embryonic tissues share a number of cellular and molecular properties, suggesting that induced pluripotent stem cells (iPSCs) may be harnessed to elicit anti-tumor responses in cancer vaccines. RNA sequencing revealed that hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a15ab42e84a61e467eae4256ea3ed2e
https://hdl.handle.net/1887/95392
https://hdl.handle.net/1887/95392