Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Thomas Osterwalder"'
Autor:
Stefan Weigel, Thomas Osterwalder, Ursina Tobler, Li Yao, Manuel Wiesli, Thomas Lehnert, Abhay Pandit, Arie Bruinink
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50714 (2012)
The treatment of critical size peripheral nerve defects represents one of the most serious problems in neurosurgery. If the gap size exceeds a certain limit, healing can't be achieved. Connection mismatching may further reduce the clinical success. T
Externí odkaz:
https://doaj.org/article/a801ff84505c4e49b964f104ed48bb9d
Publikováno v:
The Journal of Neuroscience. 24:5482-5491
The proteolytic processing of neuropeptide precursors is believed to be regulated by serine proteinase inhibitors, or serpins. Here we describe the molecular cloning and functional expression of a novel member of the serpin family,Serine protease inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a44d227da1d69572e0ef1a80fdb7a1a
https://doi.org/10.1523/jneurosci.5577-03.2004
https://doi.org/10.1523/jneurosci.5577-03.2004
Publikováno v:
Current Biology. 11:R1041-R1053
Understanding how the diverse cells of the nervous system generate sensations, memories and behaviors is a profound challenge. This is because the activity of most neurons cannot easily be monitored or individually manipulated in vivo . As a result,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50844e293b8b4c55f28cab7d938b9d1d
https://doi.org/10.1016/s0960-9822(01)00621-2
https://doi.org/10.1016/s0960-9822(01)00621-2
Autor:
Thomas Osterwalder, Albert Schinzel, Serguei Kozlov, Andreas J. Bleiker, Philipp Berger, Peter Sonderegger, Lukrecija Brecevic, Sabine P. Schrimpf, Stefan R. Krueger
Publikováno v:
Genomics. 40:55-62
Neuroserpin is a novel serine protease inhibitor of the serpin family. It has been reported as a 55-kDa glycoprotein that is secreted from the axons of cultured central and peripheral nervous system neurons. In situ hybridization and Northern blot an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c3a4eada9321f4065dcede910474f1
https://doi.org/10.1006/geno.1996.4514
https://doi.org/10.1006/geno.1996.4514
Publikováno v:
The EMBO Journal. 15:2944-2953
We have identified and chromatographically purified an axonally secreted glycoprotein of CNS and PNS neurons. Several peptides derived from it were microsequenced. Based on these sequences, a fragment of the corresponding cDNA was amplified and used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b54eda076786e9d596d16c681591fd3
https://doi.org/10.1002/j.1460-2075.1996.tb00657.x
https://doi.org/10.1002/j.1460-2075.1996.tb00657.x
Autor:
Ursina Tobler, Thomas Lehnert, Manuel Wiesli, Thomas Osterwalder, Arie Bruinink, Abhay Pandit, Li Yao, Stefan Weigel
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e50714 (2012)
PLoS ONE, Vol 7, Iss 12, p e50714 (2012)
The treatment of critical size peripheral nerve defects represents one of the most serious problems in neurosurgery. If the gap size exceeds a certain limit, healing can't be achieved. Connection mismatching may further reduce the clinical success. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ca56eae41f7d85bea21c817ff2fddf
https://pubmed.ncbi.nlm.nih.gov/23251379
https://pubmed.ncbi.nlm.nih.gov/23251379
Autor:
Haig Keshishian, Thomas Osterwalder, Gunisha K. Singh, Louise F.B. Nicholson, Gregg Roman, Ronald L. Davis
There is a critical need for genetic methods for the inducible expression of transgenes in specific cells during development. A promising approach for this is the GeneSwitch GAL4 system of Drosophila. With GeneSwitch GAL4 the expression of upstream a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a81305ac2b7e3cc5e9a59d7b7bf5f7c
https://europepmc.org/articles/PMC2206072/
https://europepmc.org/articles/PMC2206072/
Autor:
Joshua B. Atkins, Santiago B. Rompani, Weimin Zhong, Thomas Osterwalder, Yan Zhou, Haiyan Tang
Publikováno v:
Molecular and cellular biology. 25(8)
Numb proteins are evolutionarily conserved signaling molecules that make the daughter cells different after asymmetric divisions by segregating to only one daughter. They contain distinct binding motifs for alpha-adaptin (alpha-Ada) and proteins with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd16ca142fa5001e0888c9f35797c2b6
https://pubmed.ncbi.nlm.nih.gov/15798180
https://pubmed.ncbi.nlm.nih.gov/15798180
Autor:
Thomas Osterwalder, Margarete Arras, Nobusuke Tsuzuki, Paolo Cinelli, Peter Sonderegger, Philippe G. Vallet, Thomas Rülicke, Rime Madani, Chunnian N. Zhao
Publikováno v:
Molecular and cellular neurosciences. 18(5)
Because recent studies have indicated that tissue plasminogen activator (tPA) aggravates neurodegenerative processes in many neural pathologies, we studied whether the endogenous tPA antagonist neuroserpin has a neuroprotective effect in an animal mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99f139703796ae810f82fcd3ef1ae85
https://pubmed.ncbi.nlm.nih.gov/11922137
https://pubmed.ncbi.nlm.nih.gov/11922137
Autor:
Haig Keshishian, Benjamin H. White, Matthew D. Whim, Leonard K. Kaczmarek, William J. Joiner, Thomas Osterwalder, Kenneth S. Yoon
Publikováno v:
Neuron. 31(5)
We describe here a general technique for the graded inhibition of cellular excitability in vivo. Inhibition is accomplished by expressing a genetically modified Shaker K+ channel (termed the EKO channel) in targeted cells. Unlike native K+ channels,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8525701c391d78fa855219ba17bea7b
https://pubmed.ncbi.nlm.nih.gov/11567611
https://pubmed.ncbi.nlm.nih.gov/11567611