Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Thomas Oertle"'
Autor:
Christian Sengstag, Irene Knuesel, Elizabeth Weber, Thomas Oertle, Ana Lúcia Jongen-Rêlo, Eberhard Fuchs, Marianne Spengler, Christopher R. Pryce, Anna Weston, Joram Feldon
Publikováno v:
European Journal of Neuroscience. 21:1521-1535
The mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) are nuclear transcription factors that mediate many of the basal and stress functions and effects of the corticosteroid hormones, including those related to brain development. Despi
Autor:
Martin E. Schwab, Thomas Oertle, Cordula Hirsch, Claudia A. O. Stuermer, Heike Diekmann, Michael Klinger, Dietmar Heinz, Barbara Petrausch, Sylvia Hannbeck von Hanwehr
Publikováno v:
Molecular and Cellular Neuroscience. 25:205-216
Myelin-associated axon growth inhibitors such as Nogo-A/RTN4-A impair axon regeneration in the adult mammalian central nervous system (CNS). Here, we describe the cloning and expression of two independent Xenopus laevis rtn4 orthologs. As in mammals,
Autor:
F. Deisenhammer, Martin E. Schwab, Thomas Oertle, Sabrina Khantane, Kathrin Schanda, Thomas Berger, Andreas Lutterotti, Rainer Ehling, Markus Reindl, Claudia Brinkhoff, Christine E. Bandtlow
Publikováno v:
Journal of Neuroimmunology. 145:139-147
Nogo-A is a protein associated with central nervous system (CNS) myelin thought to impair regenerative responses and to suppress sprouting and plastic changes of synaptic terminals. In this study, we report that serum IgM autoantibodies to the recomb
Autor:
Christian Brösamle, Lisa Schnell, Klemens Kaupmann, Thomas Oertle, Armin Buss, Martin E. Schwab, Anna Robeva, Marjan E. van der Haar, Christine E. Bandtlow, Rüdiger Vallon, Andrea B. Huber, Marjo Simonen, Patricia Burfeind
Publikováno v:
The Journal of Neuroscience. 23:5393-5406
Nogo-A is a potent neurite growth inhibitorin vitroand plays a role both in the restriction of axonal regeneration after injury and in structural plasticity in the CNS of higher vertebrates. The regions that mediate inhibition and the topology of the
Publikováno v:
The FASEB Journal. 17:1238-1247
Reticulon (RTN) genes code for a family of proteins relatively recently described in higher vertebrates. The four known mammalian paralogues (RTN1, -2, -3, and -4/Nogo) have homologous carboxyl termini with two characteristic large hydrophobic region
Autor:
Anis Mir, Thomas Oertle, Mauro Zurini, Martin E. Schwab, Florence M Bareyre, Peter R Allegrini, Christoph Wiessner, Stefan Frentzel, Lisa Schnell
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 23:154-165
Nogo-A is a myelin-associated neurite outgrowth inhibitory protein limiting recovery and plasticity after central nervous system injury. In this study, a purified monoclonal anti—Nogo-A antibody (7B12) was evaluated in two rat stroke models with a
Publikováno v:
The Journal of Neuroscience. 22:10368-10376
The adult mammalian CNS has a limited capacity for nerve regeneration and structural plasticity. The presence of glia-derived inhibitory factors myelin-associated glycoprotein (MAG) and Nogo-A have been suggested to provide a nonpermissive environmen
Autor:
Thomas Oertle, Christine E. Bandtlow, Rüdiger Schweigreiter, Lukas A. Huber, Taras Stasyk, Igea Contarini, Lars Klimaschewski, Silke Frauscher
Publikováno v:
Proteomics. 7(24)
Reticulons (RTNs) are a large family of transmembrane proteins present throughout the eukaryotic domain in virtually every cell type. Despite their wide distribution, their function is still mostly unknown. RTN4, also termed Nogo, comes in three isof
Autor:
Dieter R. Zimmermann, Rüdiger Schweigreiter, Thomas Oertle, Barbara Niederöst, Anis Mir, Georg Dechant, Christine E. Bandtlow, Elisabeth Casademunt, Stefan Frentzel, Adrian R. Walmsley
Publikováno v:
Molecular and cellular neurosciences. 27(2)
Myelin is a major obstacle for regenerating nerve fibers of the adult mammalian central nervous system (CNS). Several proteins including Nogo-A, myelin-associated glycoprotein (MAG), oligodendrocyte myelin glycoprotein (OMgp) and the chondroitin-sulf