Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Thomas O. Moninger"'
Autor:
Brianna R. Brennecke, USeong Yang, Siming Liu, Fatma S. Ilerisoy, Beyza N. Ilerisoy, Aditya Joglekar, Lucy B. Kim, Spencer J. Peachee, Syreine L. Richtsmeier, Samuel B. Stephens, Edward A. Sander, Stefan Strack, Thomas O. Moninger, James A. Ankrum, Yumi Imai
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionWith technical advances, confocal and super-resolution microscopy have become powerful tools to dissect cellular pathophysiology. Cell attachment to glass surfaces compatible with advanced imaging is critical prerequisite but remains a co
Externí odkaz:
https://doaj.org/article/1dffe3d15e4243c39b2c5611ce7539a0
Autor:
Zhaowen Zhu, Huy Tran, Meleah M. Mathahs, Brian D. Fink, John A. Albert, Thomas O. Moninger, Jeffery L. Meier, Ming Li, Warren N. Schmidt
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract Zinc protoporphyrin (ZnPP), a naturally occurring metalloprotoporphyrin (MPP), is currently under development as a chemotherapeutic agent although its mechanism is unclear. When tested against other MPPs, ZnPP was the most effective DNA synt
Externí odkaz:
https://doaj.org/article/d5fab95c44f84180a4ec2b4b2db26636
Autor:
Yifeng Zhang, Brittany Ripley, Wei Ouyang, Miranda Sturtz, Ellen Upton, Emma Luhmann, Madeleine Vessely, Rocio Coloma, Nathan Schwery, Scott M. Anthony, Adam Goeken, Thomas O. Moninger, John T. Harty, Aloysius Klingelhutz, Emma Lundberg, David K. Meyerholz, Balaji Manicassamy, Christopher Stipp, Susana Guerra, Lilliana Radoshevich
SummaryThe ubiquitin-like protein, ISG15, can act as a cytokine or can covalently modify host and pathogen-derived proteins. The consequences of ISG15 modification on substrate fate remain unknown. Here we reveal that ISGylation of the Arp2/3 complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c32cadfbe659dd4fe44bdb6cbca2b5b5
https://doi.org/10.1101/2022.12.27.522022
https://doi.org/10.1101/2022.12.27.522022
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0166853 (2017)
INTRODUCTION:Telomerase repairs the telomeric ends of chromosomes and is active in nearly all malignant cells. Hepatitis C virus (HCV) is known to be oncogenic and potential interactions with the telomerase system require further study. We determined
Externí odkaz:
https://doaj.org/article/71fc1fe9b9fd462599db190d2f6abc15
Publikováno v:
Developmental cell. 57(18)
Pulmonary neuroendocrine cells (PNECs) are rare airway cells with potential sensory capacity linked to vagal neurons and immune cells. How PNECs sense and respond to external stimuli remains poorly understood. We discovered PNECs located within pig a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb1cb0c9c6f3aee66a5e897a3f9fd66
https://pubmed.ncbi.nlm.nih.gov/36108628
https://pubmed.ncbi.nlm.nih.gov/36108628
Autor:
Xiaopeng Li, Nathan Rossen, Patrick L Sinn, Andrew L Hornick, Benjamin R Steines, Philip H Karp, Sarah E Ernst, Ryan J Adam, Thomas O Moninger, Dana N Levasseur, Joseph Zabner
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83624 (2013)
To develop stem/progenitor cell-based therapy for cystic fibrosis (CF) lung disease, it is first necessary to identify markers of human lung epithelial progenitor/stem cells and to better understand the potential for differentiation into distinct lin
Externí odkaz:
https://doaj.org/article/314f01a312af4c3d873c8464a47216a6
Autor:
John E. Carpenter, Thomas O. Moninger, Wallen Jackson, Charles Grose, James H. Girsch, Keith W. Jarosinski
Publikováno v:
Journal of Virology
The long-term goal of this research has been to determine why VZV, when grown in cultured cells, invariably is more cell associated and has a lower titer than other alphaherpesviruses, such as herpes simplex virus 1 (HSV1) or pseudorabies virus (PRV)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b18e3e7679a06b904677d4e0147e4a
https://doi.org/10.1128/jvi.00800-20
https://doi.org/10.1128/jvi.00800-20
Acidic Submucosal Gland pH and Elevated Protein Concentration Produce Abnormal Cystic Fibrosis Mucus
Autor:
Yuliang Xie, Tony Jun Huang, David A. Stoltz, Thomas O. Moninger, Lin Lu, Michael J. Welsh, Xiao Xiao Tang
Publikováno v:
Dev Cell
In response to respiratory insults, airway submucosal glands secrete copious mucus strands to increase mucociliary clearance and protect the lung. However, in cystic fibrosis, stimulating submucosal glands has the opposite effect, disrupting mucocili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e0bb8e62180e0b625b81b7ac6d30c1
https://europepmc.org/articles/PMC7484121/
https://europepmc.org/articles/PMC7484121/
Autor:
Drake C. Bouzek, Mahmoud H. Abou Alaiwa, Daniel P. Cook, Connor P. Parker, David K. Meyerholz, Linda S. Powers, Nicholas M. Sawin, Nicholas D. Gansemer, David A. Stoltz, Ian M. Thornell, Thomas O. Moninger, Michael J. Welsh, Lynda S. Ostedgaard, James D. McMenimen
Publikováno v:
Proceedings of the National Academy of Sciences. 114:6842-6847
Gel-forming mucins, the primary macromolecular components of airway mucus, facilitate airway clearance by mucociliary transport. In cystic fibrosis (CF) altered mucus properties impair mucociliary transport. Airways primarily secrete two closely rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2135ea9ebcb374ce71480cd93ab07c0
https://doi.org/10.1073/pnas.1703228114
https://doi.org/10.1073/pnas.1703228114
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008878 (2020)
PLoS Pathogens
PLoS Pathogens
As an obligate intracellular pathogen, host cell invasion is paramount to Chlamydia trachomatis proliferation. While the mechanistic underpinnings of this essential process remain ill-defined, it is predicted to involve delivery of prepackaged effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9e8de2140e7ff009027210fd681cd2
https://doi.org/10.1371/journal.ppat.1008878
https://doi.org/10.1371/journal.ppat.1008878