Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Thomas O Metz"'
Autor:
Bernardo Blanco-Sánchez, Aurélie Clément, Sarah J Stednitz, Jennifer Kyle, Judy L Peirce, Marcie McFadden, Jeremy Wegner, Jennifer B Phillips, Ellen Macnamara, Yan Huang, David R Adams, Camilo Toro, William A Gahl, May Christine V Malicdan, Cynthia J Tifft, Erika M Zink, Kent J Bloodsworth, Kelly G Stratton, Undiagnosed Diseases Network, David M Koeller, Thomas O Metz, Philip Washbourne, Monte Westerfield
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009156 (2020)
[This corrects the article DOI: 10.1371/journal.pgen.1008841.].
Externí odkaz:
https://doaj.org/article/27535b7c4ebd48a0a9b693598f19ae60
Autor:
Bernardo Blanco-Sánchez, Aurélie Clément, Sara J Stednitz, Jennifer Kyle, Judy L Peirce, Marcie McFadden, Jeremy Wegner, Jennifer B Phillips, Ellen Macnamara, Yan Huang, David R Adams, Camilo Toro, William A Gahl, May Christine V Malicdan, Cynthia J Tifft, Erika M Zink, Kent J Bloodsworth, Kelly G Stratton, Undiagnosed Diseases Network, David M Koeller, Thomas O Metz, Philip Washbourne, Monte Westerfield
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008841 (2020)
Hypomyelination, a neurological condition characterized by decreased production of myelin sheets by glial cells, often has no known etiology. Elucidating the genetic causes of hypomyelination provides a better understanding of myelination, as well as
Externí odkaz:
https://doaj.org/article/013d3575604347cf9f765d5b55ed4f6d
Autor:
Bryan Stanfill, Sarah Reehl, Lisa Bramer, Ernesto S Nakayasu, Stephen S Rich, Thomas O Metz, Marian Rewers, Bobbie-Jo Webb-Robertson
Publikováno v:
Biomedical Engineering and Computational Biology, Vol 10 (2019)
Classification is a common technique applied to ’omics data to build predictive models and identify potential markers of biomedical outcomes. Despite the prevalence of case-control studies, the number of classification methods available to analyze
Externí odkaz:
https://doaj.org/article/64aec4ba052946d9a05e7a2e9b4d85ce
Autor:
Amy E Bryant, Michael J Aldape, Clifford R Bayer, Eva J Katahira, Laura Bond, Carrie D Nicora, Thomas L Fillmore, Therese R W Clauss, Thomas O Metz, Bobbie-Jo Webb-Robertson, Dennis L Stevens
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172486 (2017)
BACKGROUND:Acute muscle injuries are exceedingly common and non-steroidal anti-inflammatory drugs (NSAIDs) are widely consumed to reduce the associated inflammation, swelling and pain that peak 1-2 days post-injury. While prophylactic use or early ad
Externí odkaz:
https://doaj.org/article/debe4290161745cba72e49bf78a41bbd
Model‐driven multi‐omic data analysis elucidates metabolic immunomodulators of macrophage activation
Autor:
Aarash Bordbar, Monica L Mo, Ernesto S Nakayasu, Alexandra C Schrimpe‐Rutledge, Young‐Mo Kim, Thomas O Metz, Marcus B Jones, Bryan C Frank, Richard D Smith, Scott N Peterson, Daniel R Hyduke, Joshua N Adkins, Bernhard O Palsson
Publikováno v:
Molecular Systems Biology, Vol 8, Iss 1, Pp 1-12 (2012)
Abstract Macrophages are central players in immune response, manifesting divergent phenotypes to control inflammation and innate immunity through release of cytokines and other signaling factors. Recently, the focus on metabolism has been reemphasize
Externí odkaz:
https://doaj.org/article/c37457a55eca4997a9b8ad77bb45ab60
Autor:
Young-Mo eKim, Shane eNowack, Millie T. Olsen, Eric D Becraft, Jason M Wood, Vera eThiel, Isaac eKlapper, Michael eKühl, Jim K Fredrickson, Donald A Bryant, David M Ward, Thomas O Metz
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Dynamic environmental factors such as light, nutrients, salt, and temperature continuously affect chlorophototrophic microbial mats, requiring adaptive and acclimative responses to stabilize composition and function. Quantitative metabolomics analysi
Externí odkaz:
https://doaj.org/article/f7355d80ac83442fa2d10ed5faa4259c
Autor:
Kyle R Pomraning, Siwei Wei, Sue A Karagiosis, Young-Mo Kim, Alice C Dohnalkova, Bruce W Arey, Erin L Bredeweg, Galya Orr, Thomas O Metz, Scott E Baker
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123188 (2015)
Yarrowia lipolytica is an oleaginous ascomycete yeast that accumulates large amounts of lipids and has potential as a biofuel producing organism. Despite a growing scientific literature focused on lipid production by Y. lipolytica, there remain signi
Externí odkaz:
https://doaj.org/article/1c57a16d33c04a3899d1c640a0ecf17d
Autor:
Jessica K Cole, Janine R Hutchison, Ryan Scott Renslow, Young-Mo eKim, William B Chrisler, Heather E Engelmann, Alice C Dohnalkova, Dehong eHu, Thomas O Metz, Jim K Fredrickson, Stephen R Lindemann
Publikováno v:
Frontiers in Microbiology, Vol 5 (2014)
Microbial autotroph-heterotroph interactions influence biogeochemical cycles on a global scale, but the diversity and complexity of natural systems and their intractability to in situ manipulation make it challenging to elucidate the principles gover
Externí odkaz:
https://doaj.org/article/1501c5ca76594e409754bbbe5877a574
Autor:
Brooke L Deatherage Kaiser, Jie Li, James A Sanford, Young-Mo Kim, Scott R Kronewitter, Marcus B Jones, Christine T Peterson, Scott N Peterson, Bryan C Frank, Samuel O Purvine, Joseph N Brown, Thomas O Metz, Richard D Smith, Fred Heffron, Joshua N Adkins
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67155 (2013)
The potential for commensal microorganisms indigenous to a host (the 'microbiome' or 'microbiota') to alter infection outcome by influencing host-pathogen interplay is largely unknown. We used a multi-omics "systems" approach, incorporating proteomic
Externí odkaz:
https://doaj.org/article/ef29b286be3f4339b220d39477074a10
Autor:
Hugh D Mitchell, Amie J Eisfeld, Amy C Sims, Jason E McDermott, Melissa M Matzke, Bobbi-Jo M Webb-Robertson, Susan C Tilton, Nicolas Tchitchek, Laurence Josset, Chengjun Li, Amy L Ellis, Jean H Chang, Robert A Heegel, Maria L Luna, Athena A Schepmoes, Anil K Shukla, Thomas O Metz, Gabriele Neumann, Arndt G Benecke, Richard D Smith, Ralph S Baric, Yoshihiro Kawaoka, Michael G Katze, Katrina M Waters
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69374 (2013)
Respiratory infections stemming from influenza viruses and the Severe Acute Respiratory Syndrome corona virus (SARS-CoV) represent a serious public health threat as emerging pandemics. Despite efforts to identify the critical interactions of these vi
Externí odkaz:
https://doaj.org/article/f94e5a062b6045f4805aeed27ac4fbc6