Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Thomas Nix"'
Autor:
Thomas Nix, Lance W. Traub
Publikováno v:
Journal of Aircraft. 49:183-192
A low-speed wind-tunnel investigation was conducted to evaluate the behavior of a morphable biplane configuration.Morphing encompassed a rotation of the wings around the fuselage such that they could bemerged to form amonoplane or split to form anX-s
Publikováno v:
Journal of Aircraft. 47:1435-1439
D ELTA wings are poor lift generators. An often-employed design approach to ameliorate the low lift production is to sharpen thewing’s leading edge. A consequence of the enforced flow separation is the formation of leading-edge vortices. The vortic
Publikováno v:
Journal of Aircraft. 46:1815-1818
T HE characterization of the aerodynamic performance of airfoils has been the subject of focused study since the 1910s. An implicitly assumed requirement is that the model fidelity (experimental or computational) is such that it is an exact rendering
Neues zur Geologie und Ingenieurgeologie des UNESCO-Welterbes Grube Messel bei Darmstadt (Südhessen)
Publikováno v:
Jahresberichte und Mitteilungen des Oberrheinischen Geologischen Vereins. 83:285-292
Autor:
Franz-Jürgen Harms, Thomas Nix, Herward Molek, Fred Rosenberg, Gabriele Aderhold, Ingrid Hoffmann
Publikováno v:
Jahresberichte und Mitteilungen des Oberrheinischen Geologischen Vereins. 83:145-183
Autor:
Motahareh Arjomandnejad, Katelyn Sylvia, Meghan Blackwood, Thomas Nixon, Qiushi Tang, Manish Muhuri, Alisha M. Gruntman, Guangping Gao, Terence R. Flotte, Allison M. Keeler
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 490-506 (2021)
Immune responses to adeno-associated virus (AAV) capsids limit the therapeutic potential of AAV gene therapy. Herein, we model clinical immune responses by generating AAV capsid-specific chimeric antigen receptor (AAV-CAR) T cells. We then modulate i
Externí odkaz:
https://doaj.org/article/1d3794b4a1154ad0b895efd390f57d2a
Autor:
Manish Muhuri, Wei Zhan, Yukiko Maeda, Jia Li, Anoushka Lotun, Jennifer Chen, Katelyn Sylvia, Ishani Dasgupta, Motahareh Arjomandnejad, Thomas Nixon, Allison M. Keeler, Sangeetha Manokaran, Ran He, Qin Su, Phillip W. L. Tai, Guangping Gao
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Recombinant adeno-associated virus (rAAV) platforms hold promise for in vivo gene therapy but are undermined by the undesirable transduction of antigen presenting cells (APCs), which in turn can trigger host immunity towards rAAV-expressed transgene
Externí odkaz:
https://doaj.org/article/01510ca4e9254713881c8470321ee966
Autor:
Thomas Nixon, Allan J. Richards, Adrian Lomas, Stephen Abbs, Pradeep Vasudevan, Annie McNinch, Philip Alexander, Martin P. Snead
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 9, Pp n/a-n/a (2020)
Abstract Background Type 2 Stickler syndrome is usually a dominant disorder resulting from pathogenic variants in COL11A1 encoding the alpha 1 chain of type XI collagen. Typical molecular changes result in either substitution of an obligate glycine w
Externí odkaz:
https://doaj.org/article/fff2428e7d0945f08408501944c8b8df
Autor:
Alan C. Cheng, Elizabeth M. Doherty, Sheree Johnstone, Erin F. DiMauro, Jennifer Dao, Abhinav Luthra, Jay Ye, Jie Tang, Thomas Nixey, Xiaoshan Min, Philip Tagari, Les P. Miranda, Zhulun Wang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Small molecules and antibodies each have advantages and limitations as therapeutics. Here, we present for the first time to our knowledge, the structure-guided design of “chemibodies” as small molecule-antibody hybrids that offer dual re
Externí odkaz:
https://doaj.org/article/03c054e59aee48aa9fd15ab0e960b901
Autor:
James Thomas Nix
Publikováno v:
Southern Medical Journal. 25:196-200