Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Thomas Nicolaus"'
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Staphylococcal pathogens adhere to their human targets using adhesins, which can withstand extremely high forces. Here, authors use single-molecule force spectroscopy to determine the similarly high unfolding forces of B domains that link the adhesin
Externí odkaz:
https://doaj.org/article/3f2523c006d44bfc9a24d45ca7291cb5
Autor:
Magnus Bauer, Sophia Gruber, Adina Hausch, Marcelo Cardoso dos Reis Melo, Priscila Gomes, Thomas Nicolaus, Lukas Milles, Hermann Gaub, Rafael Bernardi, Jan Lipfert
Viruses mutate under a variety of selection pressures, allowing them to continuously adapt to their hosts. Mutations in SARS-CoV-2 have shown effective evasion of population immunity and increased affinity to host factors, in particular to the cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::525e166daded524de2597a8735cfee47
https://doi.org/10.21203/rs.3.rs-2450634/v1
https://doi.org/10.21203/rs.3.rs-2450634/v1
Autor:
Magnus S. Bauer, Sophia Gruber, Adina Hausch, Marcelo C.R. Melo, Priscila S.F.C. Gomes, Thomas Nicolaus, Lukas F. Milles, Hermann E. Gaub, Rafael C. Bernardi, Jan Lipfert
Viruses mutate under a variety of selection pressures, allowing them to continuously adapt to their hosts. Mutations in SARS-CoV-2 have shown effective evasion of population immunity and increased affinity to host factors, in particular to the cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b68f93610cee19908aee682d4b7f321
https://doi.org/10.1101/2023.01.06.522349
https://doi.org/10.1101/2023.01.06.522349
Autor:
Magnus S. Bauer, Sophia Gruber, Adina Hausch, Lukas F. Milles, Thomas Nicolaus, Leonard C. Schendel, Pilar López Navajas, Erik Procko, Daniel Lietha, Rafael C. Bernardi, Hermann E. Gaub, Jan Lipfert
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
SARS-CoV-2 infections are initiated by attachment of the receptor-binding domain (RBD) on the viral Spike protein to angiotensin-converting enzyme-2 (ACE2) on human host cells. This critical first step occurs in dynamic environments, where external f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2a4ab6fe9d91075750bc40e791c3d7
Autor:
Carola Lampe, Pauline J. Kolbeck, Thomas Nicolaus, Jan Lipfert, Willem Vanderlinden, Wout Frederickx, Alexander S. Urban, Cécile Moucheron, Sebastian F. Konrad
Publikováno v:
Chemical communications, 55 (60
Ru(ii)-complexes with polyazaaromatic ligands can undergo direct electron transfer with guanine nucleobases on blue light excitation that results in DNA lesions with phototherapeutic potential. Here we use single molecule approaches to demonstrate DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6bef9ff25d0c2d317ed53cf97c99ac6
https://doi.org/10.1039/c9cc02838b
https://doi.org/10.1039/c9cc02838b
Autor:
Magnus S. Bauer, Jan Lipfert, Thomas Nicolaus, Leonard C. Schendel, Lukas F. Milles, Hermann E. Gaub, Sophia Gruber
The current COVID-19 pandemic has a devastating global impact and is caused by the SARS-CoV-2 virus. SARS-CoV-2 attaches to human host cells through interaction of its receptor binding domain (RBD) located on the viral Spike (S) glycoprotein with ang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c344ad8e400979a4e4d0fdb69d80e1
https://doi.org/10.1101/2020.09.27.315796
https://doi.org/10.1101/2020.09.27.315796
Autor:
Christian Gebhardt, Thorben Cordes, Jan Lipfert, Pauline J. Kolbeck, Thomas Nicolaus, Willem Vanderlinden
SYBR Gold is a commonly used and particularly bright fluorescent DNA stain, however, its binding mode to DNA remains controversial. Here, we quantitate SYBR Gold binding to DNA using two complementary approaches. We use mechanical micromanipulation w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5329f216bfe8054239f7c30b72869709
https://doi.org/10.1101/2020.05.23.112631
https://doi.org/10.1101/2020.05.23.112631
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1814
Magnetic tweezers permit application of precisely calibrated stretching forces to nucleic acid molecules tethered between a surface and superparamagnetic beads. In addition, magnetic tweezers can control the tethers' twist. Here, we focus on recent e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d2d009df870ec167d1d0844dab2a63a
https://pubmed.ncbi.nlm.nih.gov/29956228
https://pubmed.ncbi.nlm.nih.gov/29956228
Publikováno v:
Methods in Molecular Biology ISBN: 9781493985906
Magnetic tweezers permit application of precisely calibrated stretching forces to nucleic acid molecules tethered between a surface and superparamagnetic beads. In addition, magnetic tweezers can control the tethers' twist. Here, we focus on recent e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f471acb12abe508715b6ef82dca1e91
https://doi.org/10.1007/978-1-4939-8591-3_6
https://doi.org/10.1007/978-1-4939-8591-3_6
Publikováno v:
Biomacromolecules. 17(4)
Repetitive protein-based polymers are important for many applications in biotechnology and biomaterials development. Here we describe the sequential additive ligation of highly repetitive DNA sequences, their assembly into genes encoding protein-poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e893d79eb575e3763ae8b5f38ced49b
https://pubmed.ncbi.nlm.nih.gov/26974874
https://pubmed.ncbi.nlm.nih.gov/26974874