Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Thomas Nerreter"'
Autor:
Florian Märkl, Christoph Schultheiß, Murtaza Ali, Shih-Shih Chen, Marina Zintchenko, Lukas Egli, Juliane Mietz, Obinna Chijioke, Lisa Paschold, Sebastijan Spajic, Anne Holtermann, Janina Dörr, Sophia Stock, Andreas Zingg, Heinz Läubli, Ignazio Piseddu, David Anz, Marcus Dühren-von Minden, Tianjiao Zhang, Thomas Nerreter, Michael Hudecek, Susana Minguet, Nicholas Chiorazzi, Sebastian Kobold, Mascha Binder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The concept of precision cell therapy targeting tumor-specific mutations is appealing but requires surface-exposed neoepitopes, which is a rarity in cancer. B cell receptors (BCR) of mature lymphoid malignancies are exceptional in that they
Externí odkaz:
https://doaj.org/article/f556d70ecba646069501e54817da7995
Autor:
Leopold Diener, Nicolas Goedert, Marah Alskalini, Andrea Cattaneo, Camelia Monoranu, Julian Hübner, Tim Schulz, Almuth Keßler, Ralf-Ingo Ernestus, Carsten Hagemann, Mario Löhr, Maria Breun, Thomas Nerreter, Vera Nickl
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 101843- (2023)
Externí odkaz:
https://doaj.org/article/e0f1122a52df459281941845ff727043
Autor:
Marah Alsalkini, Julian Hübner, Leopold Diener, Camelia Monoranu, Andrea Cattaneo, Almuth Keßler, Tim Schulz, Carsten Hagemann, Ralf-Ingo Ernestus, Mario Löhr, Maria Breun, Thomas Nerreter, Vera Nickl
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 102149- (2023)
Externí odkaz:
https://doaj.org/article/3bb45c8c8d3f4ddd9cf9e715e4894154
Autor:
Maik Luu, Zeno Riester, Adrian Baldrich, Nicole Reichardt, Samantha Yuille, Alessandro Busetti, Matthias Klein, Anne Wempe, Hanna Leister, Hartmann Raifer, Felix Picard, Khalid Muhammad, Kim Ohl, Rossana Romero, Florence Fischer, Christian A. Bauer, Magdalena Huber, Thomas M. Gress, Matthias Lauth, Sophia Danhof, Tobias Bopp, Thomas Nerreter, Imke E. Mulder, Ulrich Steinhoff, Michael Hudecek, Alexander Visekruna
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The activity of immune cells can be regulated by the microbiome. Here, the authors show that the fatty acids pentanoate and butyrate—normally released by the microbiome—increase the anti-tumour activity of cytotoxic T lymphocytes and chimeric ant
Externí odkaz:
https://doaj.org/article/b049d4b46e18405fa995dd666bce268c
Autor:
Thomas Nerreter, Sebastian Letschert, Ralph Götz, Sören Doose, Sophia Danhof, Hermann Einsele, Markus Sauer, Michael Hudecek
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
CD19 CAR-T cells have achieved some success in treating myeloma patients despite the limited detection of the CD19 antigen. Here, the authors show using dSTORM that 10/14 myeloma samples studied express ultra-low levels of CD19, which are sufficient
Externí odkaz:
https://doaj.org/article/406f8042514e434299b754fc01f1e692
Autor:
Michael Hudecek, Anna Christina Dragon, Katharina Zimmermann, Thomas Nerreter, Deborah Sandfort, Julia Lahrberg, Stephan Klöß, Christina Kloth, Caroline Mangare, Agnes Bonifacius, Sabine Tischer-Zimmermann, Rainer Blasczyk, Britta Maecker-Kolhoff, Barbara Uchanska-Ziegler, Hinrich Abken, Axel Schambach, Britta Eiz-Vesper
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Immunosuppressive therapy or T-cell depletion in transplant patients can cause uncontrolled growth of Epstein-Barr virus (EBV)-infected B cells resulting in post-transplant lymphoproliferative disease (PTLD). Current treatment options do n
Externí odkaz:
https://doaj.org/article/348dcb5caf3b46bf9710f3c4a8963e42
Autor:
Martin Michaelis, Florian Rothweiler, Thomas Nerreter, Marijke van Rikxoort, Mohsen Sharifi, Michael Wiese, Taravat Ghafourian, Jindrich Cinatl
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 17, Iss 1 (2014)
PURPOSE: The clinically approved oncogenic BRAF inhibitor PLX4032 (vemurafenib) was shown to be a substrate of the ATP-binding cassette (ABC) transporter ABCB1. Here, we compared PLX4032 and its structurally closely related precursor compound PLX4720
Externí odkaz:
https://doaj.org/article/37ecbb858edc4aaab26762a51deea2a7
Autor:
Martin Michaelis, Florian Rothweiler, Thomas Nerreter, Mohsen Sharifi, Taravat Ghafourian, Jindrich Cinatl
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 17, Iss 1 (2014)
PURPOSE: The prominent ATP-binding cassette (ABC) transporters ABCB1, ABCC1, and ABCG2 are involved in substance transport across physiological barriers and therefore in drug absorption, distribution, and elimination. They also mediate multi-drug res
Externí odkaz:
https://doaj.org/article/fc16bdea3c7d43fe8809fe3704016669
Autor:
Vera Nickl, Juliana Eck, Nicolas Goedert, Julian Hübner, Thomas Nerreter, Carsten Hagemann, Ralf-Ingo Ernestus, Tim Schulz, Robert Carl Nickl, Almuth Friederike Keßler, Mario Löhr, Andreas Rosenwald, Maria Breun, Camelia Maria Monoranu
Publikováno v:
Cancers; Volume 15; Issue 10; Pages: 2698
While glioblastoma (GBM) is still challenging to treat, novel immunotherapeutic approaches have shown promising effects in preclinical settings. However, their clinical breakthrough is hampered by complex interactions of GBM with the tumor microenvir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841ffee6f12f4c7b70e8846923a1c6c3
Autor:
Michelle Seif, Tamara Katharina Kakoschke, Frank Ebel, Marina Maria Bellet, Nora Trinks, Giorgia Renga, Marilena Pariano, Luigina Romani, Beeke Tappe, David Espie, Emmanuel Donnadieu, Kerstin Hünniger, Antje Häder, Markus Sauer, Diane Damotte, Marco Alifano, P. Lewis White, Matthijs Backx, Thomas Nerreter, Markus Machwirth, Oliver Kurzai, Sabrina Prommersberger, Hermann Einsele, Michael Hudecek, Jürgen Löffler
Publikováno v:
Science Translational Medicine. 14
Aspergillus fumigatus is a ubiquitous mold that can cause severe infections in immunocompromised patients, typically manifesting as invasive pulmonary aspergillosis (IPA). Adaptive and innate immune cells that respond to A. fumigatus are present in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd98b073c62f9b7054610bb340b0112
https://doi.org/10.1126/scitranslmed.abh1209
https://doi.org/10.1126/scitranslmed.abh1209