Výsledky vyhledávání - "Thomas Navndrup Eskehave"

Identifying specific profiles in patients with different degrees of painful knee osteoarthritis based on serological biochemical and mechanistic pain biomarkers: a diagnostic approach based on cluster analysis

Autor: Line Lindhardt Egsgaard, Anne-Christine Bay-Jensen, Thomas Navndrup Eskehave, Hans Christian Hoeck, Lars Arendt-Nielsen

Publikováno v: Egsgaard, L L, Eskehave, T N, Bay-Jensen, A C, Hoeck, H C & Arendt-Nielsen, L 2015, ' Identifying specific profiles in patients with different degrees of painful knee osteoarthritis based on serological biochemical and mechanistic pain biomarkers : a diagnostic approach based on cluster analysis ', Pain, vol. 156, no. 1, pp. 96-107 . https://doi.org/10.1016/j.pain.0000000000000011

Biochemical and pain biomarkers can be applied to patients with painful osteoarthritis profiles and may provide more details compared with conventional clinical tools. The aim of this study was to identify an optimal combination of biochemical and pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fa1cd16d7dbc202865d95f1e62edcb
https://pubmed.ncbi.nlm.nih.gov/25599306

Zobrazit plný text záznamu

Pain sensitization and degenerative changes are associated with aberrant plantar loading in patients with painful knee osteoarthritis

Autor: Lise Skøtt Gregersen, Turid Røsland, Thomas Navndrup Eskehave, Uwe G. Kersting, Lars Arendt-Nielsen

Publikováno v: Røsland, T, Gregersen, L S, Eskehave, T N, Kersting, U G & Arendt-Nielsen, L 2015, ' Pain sensitization and degenerative changes are associated with aberrant plantar loading in patients with painful knee osteoarthritis ', Scandinavian Journal of Rheumatology, vol. 44, no. 1, pp. 61-69 . https://doi.org/10.3109/03009742.2014.923038

This study focused on the biomechanical implications of knee osteoarthritis (OA) and the association with pain. The plantar loading force distribution of the foot was determined and correlated to degenerative knee changes, function, pain intensity, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3ea8433e91b85e3a83c1d70ab656da
https://pubmed.ncbi.nlm.nih.gov/25296895

Zobrazit plný text záznamu

Identification and characterisation of osteoarthritis patients with inflammation derived tissue turnover

Autor: Morten A. Karsdal, Anne Sofie Siebuhr, Claus Christiansen, Line Lindhardt Egsgaard, Hans Christian Hoeck, Lars Arendt-Nielsen, Ole Simonsen, Kristian Kjær Petersen, Anne-Christine Bay-Jensen, Thomas Navndrup Eskehave

Publikováno v: Siebuhr, A S, Petersen, K K, Arendt-Nielsen, L, Egsgaard, L L, Eskehave, T, Christiansen, C, Simonsen, O, Hoeck, H C, Karsdal, M A & Bay-Jensen, A C 2014, ' Identification and characterisation of osteoarthritis patients with inflammation derived tissue turnover ', Osteoarthritis and Cartilage, vol. 22, no. 1, pp. 44–50 . https://doi.org/10.1016/j.joca.2013.10.020
Europe PubMed Central

SummaryObjectivesOsteoarthritis (OA) is a degenerative disease with a subset of patients experiencing joint inflammation, but C-reactive protein (CRP) has shown limited use in OA as a diagnostic marker. The aim was to identify subpopulations of patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2892894722d6ed9a8c45f5443355d7b1
https://vbn.aau.dk/da/publications/306fe397-0c92-449e-a2e5-c08c5b61f9fd

Zobrazit plný text záznamu

Towards personalized health care in OA?:identification of osteoarthritis (OA) patients into four phenotypic classes depending on their level of cartilage degradation and connective tissue inflammation

Autor: Morten Karsdal, Ole Simonsen, L. Arendt-Nilesen, Anne Sofie Siebuhr, Line Lindhardt Egsgaard, Thomas Navndrup Eskehave, H. Hoegh, A.-C. Bay-Jensen, Kristian Kjær Petersen

Publikováno v: Bay-Jensen, A-C, Siebuhr, A, Egsgaard, L L, Simonsen, O, Eskehave, T N, Arendt-Nielsen, L, Petersen, K K, Hoegh, H & Karsdal, M 2014, ' Towards personalized health care in OA? identification of osteoarthritis (OA) patients into four phenotypic classes depending on their level of cartilage degradation and connective tissue inflammation ', Osteoarthritis and Cartilage, vol. 22, no. Suppl. S, pp. S73, No. 114 . https://doi.org/10.1016/j.joca.2014.02.148

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab1502486e250c98f6b06e4d85853f5
https://vbn.aau.dk/da/publications/1315ca71-57a7-4d37-9238-65d3e372566e

Zobrazit plný text záznamu

Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammation

Autor: J. Wang, Di Su, Kristian Kjær Petersen, Anne Sofie Siebuhr, Anne-Christine Bay-Jensen, Thomas Navndrup Eskehave, Yi He, Ole Simonsen, Hans Christian Hoeck, Lars Arendt-Nielsen, Qinlong Zheng, Niels Ulrik Brandt-Hansen, Morten A. Karsdal

Publikováno v: He, Y, Siebuhr, A S, Brandt-Hansen, N U, Wang, J, Su, D, Zheng, Q, Simonsen, O, Petersen, K K, Arendt-Nielsen, L, Eskehave, T, Hoeck, H C, Karsdal, M A & Bay-Jensen, A C 2014, ' Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammation ', B M C Musculoskeletal Disorders, vol. 15, pp. 309 . https://doi.org/10.1186/1471-2474-15-309
BMC Musculoskeletal Disorders

Background Osteoarthritis (OA) is the most common degenerative joint disease, of which the pathogenesis is inadequately understood. Hypertrophy-like changes have been observed as part of the progression of OA. The aim of the study was to develop and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db440041b2b363a6b9e8d8fa1fa3b82
https://vbn.aau.dk/da/publications/aafc04dc-7872-4ea1-9901-6354f97f1e5d

Zobrazit plný text záznamu

Brain delivery systems via mechanism independent of receptor-mediated endocytosis and adsorptive-mediated endocytosis

Autor: Thomas Linemann, Joachim Høg Mortensen, Louiza Bohn Thomsen, Torben Moos, Kristian Gaarn du Jardin, Jacek Lichota, Thomas Navndrup Eskehave

Publikováno v: Thomsen, L B, Lichota, J, Eskehave, T N, Linemann, T, Mortensen, J H, du Jardin, K G & Moos, T 2012, ' Brain delivery systems via mechanism independent of receptor-mediated endocytosis and adsorptive-mediated endocytosis ', Current Pharmaceutical Biotechnology, vol. 13, no. 12, pp. 2349-2354 . https://doi.org/10.2174/138920112803341842
Thomsen, L B, Lichota, J, Eskehave, T N, Linemann, T, Mortensen, J H, du Jardin, K G & Moos, T 2012, ' Brain delivery systems via mechanism independent of receptor-mediated endocytosis and adsorptive-mediated endocytosis ', Current Pharmaceutical Biotechnology, vol. 13, no. 12, pp. 2349-54 .

The endothelial cells of the brain form the blood-brain barrier (BBB) that denotes a major restraint for drug entry to the brain. Traditional attempts to bypass the BBB have been by formulation of drugs with lipophilicity or low molecular weight desi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d69c5abbb5d1f65f8d3f7dc15d6f565
https://vbn.aau.dk/da/publications/955c7cd8-da10-43bb-99d4-c99417fd999b

Zobrazit plný text záznamu

Synovitis, pain and serological biomarkers

Autor: Morten Karsdal, Lars Arendt-Nielsen, Ole Simonsen, Thomas Navndrup Eskehave, Kristian Kjær Petersen, Anne Sofie Siebuhr, A.-C. Bay-Jensen

Publikováno v: Petersen, K K, Arendt-Nielsen, L, Eskehave, T, Karsdal, M A, Simonsen, O, Siebuhr, A & Bay-Jensen, A-C 2014, ' Synovitis, pain and serological biomarkers ', Osteoarthritis and Cartilage, vol. 22, no. Suppl. S, pp. S411-S412, No. 740 . https://doi.org/10.1016/j.joca.2014.02.775

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a647182d97a3b56edc259fedbd7693c1

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání