Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Thomas Muster"'
Autor:
Raveen Rathnasinghe, Lauren A. Chang, Rebecca Pearl, Sonia Jangra, Amy Aspelund, Alaura Hoag, Soner Yildiz, Ignacio Mena, Weina Sun, Madhumathi Loganathan, Nicholas Alexander Crossland, Hans P. Gertje, Anna Elise Tseng, Sadaf Aslam, Randy A. Albrecht, Peter Palese, Florian Krammer, Michael Schotsaert, Thomas Muster, Adolfo García-Sastre
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Influenza viruses pose a threat to public health as evidenced by severe morbidity and mortality in humans on a yearly basis. Given the constant changes in the viral glycoproteins owing to antigenic drift, seasonal influenza vaccines need to
Externí odkaz:
https://doaj.org/article/dccfdfa0d19945a6be803b54e7f7865b
Autor:
Raveen Rathnasinghe, Mirella Salvatore, Hongyong Zheng, Sonia Jangra, Thomas Kehrer, Ignacio Mena, Michael Schotsaert, Thomas Muster, Peter Palese, Adolfo García-Sastre
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The influenza A non-structural protein 1 (NS1) is known for its ability to hinder the synthesis of type I interferon (IFN) during viral infection. Influenza viruses lacking NS1 (ΔNS1) are under clinical development as live attenuated human
Externí odkaz:
https://doaj.org/article/40093ba6def04ffd8471e4167f233f58
Autor:
Christoph Jindra, Edmund K. Hainisch, Andrea Rümmele, Markus Wolschek, Thomas Muster, Sabine Brandt
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Bovine papillomaviruses types 1 and 2 (BPV1, BPV2) commonly induce skin tumours termed sarcoids in horses and other equids. Sarcoids seriously compromise the health and welfare of affected individuals due to their propensity to resist treatment and r
Externí odkaz:
https://doaj.org/article/98c6f48e41374c93a83be325cb53b4c3
Autor:
Christoph Jindra, Bettina Huber, Saeed Shafti-Keramat, Markus Wolschek, Boris Ferko, Thomas Muster, Sabine Brandt, Reinhard Kirnbauer
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138722 (2015)
Persistent infection with high-risk human papillomavirus (HPV) types, most often HPV16 and HPV18, causes all cervical and most anal cancers, and a subset of vulvar, vaginal, penile and oropharyngeal carcinomas. Two prophylactic virus-like particle (V
Externí odkaz:
https://doaj.org/article/cc9a5bc4b1a546f48ac8593e1eb1e405
Autor:
Christoph Jindra, Bettina Huber, Saeed Shafti-Keramat, Markus Wolschek, Boris Ferko, Thomas Muster, Sabine Brandt, Reinhard Kirnbauer
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143269 (2015)
Externí odkaz:
https://doaj.org/article/b2f2bac9cddb4de6a49b8de051100c90
Autor:
Hae-Jung Park, Boris Ferko, Young-Ho Byun, Joo-Hye Song, Gye-Yeong Han, Elisabeth Roethl, Andrej Egorov, Thomas Muster, Baiklin Seong, Mi-Na Kweon, Manki Song, Cecil Czerkinsky, Huan H Nguyen
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39921 (2012)
The nonstructural protein 1 (NS1) of influenza A virus (IAV) enables the virus to disarm the host cell type 1 IFN defense system. Mutation or deletion of the NS1 gene leads to attenuation of the virus and enhances host antiviral response making such
Externí odkaz:
https://doaj.org/article/b0511f0df3d7418ca52e1076f2754670
Autor:
Marijke van Rikxoort, Martin Michaelis, Markus Wolschek, Thomas Muster, Andrej Egorov, Joachim Seipelt, Hans Wilhelm Doerr, Jindrich Cinatl
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36506 (2012)
Oncolytic influenza A viruses with deleted NS1 gene (delNS1) replicate selectively in tumour cells with defective interferon response and/or activated Ras/Raf/MEK/ERK signalling pathway. To develop a delNS1 virus with specific immunostimulatory prope
Externí odkaz:
https://doaj.org/article/04d8e89c378c4bbaa02bf801b1f65c79
Autor:
Brigitte M Krenn, Andrej Egorov, Ekaterina Romanovskaya-Romanko, Markus Wolschek, Sabine Nakowitsch, Tanja Ruthsatz, Bettina Kiefmann, Alexander Morokutti, Johannes Humer, Janina Geiler, Jindrich Cinatl, Martin Michaelis, Nina Wressnigg, Sanda Sturlan, Boris Ferko, Oleg V Batishchev, Andrey V Indenbom, Rong Zhu, Markus Kastner, Peter Hinterdorfer, Oleg Kiselev, Thomas Muster, Julia Romanova
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18577 (2011)
BACKGROUND: H5N1 influenza vaccines, including live intranasal, appear to be relatively less immunogenic compared to seasonal analogs. The main influenza virus surface glycoprotein hemagglutinin (HA) of highly pathogenic avian influenza viruses (HPAI
Externí odkaz:
https://doaj.org/article/d9c2e3f4d7b94f30b4cd05496ba9f848
Autor:
Julia Romanova, Brigitte M Krenn, Markus Wolschek, Boris Ferko, Ekaterina Romanovskaja-Romanko, Alexander Morokutti, Anna-Polina Shurygina, Sabine Nakowitsch, Tanja Ruthsatz, Bettina Kiefmann, Ulrich König, Michael Bergmann, Monika Sachet, Shobana Balasingam, Alexander Mann, John Oxford, Martin Slais, Oleg Kiselev, Thomas Muster, Andrej Egorov
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5984 (2009)
BACKGROUND:We developed a novel intranasal influenza vaccine approach that is based on the construction of replication-deficient vaccine viruses that lack the entire NS1 gene (DeltaNS1 virus). We previously showed that these viruses undergo abortive
Externí odkaz:
https://doaj.org/article/b3e0973ffb1a4402a23935312dac8bf4
Autor:
Mirella Salvatore, Sonia Jangra, Ignacio Mena, Raveen Rathnasinghe, Peter Palese, Thomas Kehrer, Hongyong Zheng, Michael Schotsaert, Thomas Muster, Adolfo García-Sastre
Publikováno v:
Scientific Reports
Research Square
article-version (status) pre
article-version (number) 1
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Research Square
article-version (status) pre
article-version (number) 1
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
The influenza A non-structural protein 1 (NS1) is known for its ability to hinder the synthesis of type I interferon (IFN) during viral infection. Influenza viruses lacking NS1 (ΔNS1) are under clinical development as live attenuated human influenza