Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Thomas Mrowiec"'
Autor:
Juliane Manitz, Aslihan Gerhold‐Ay, Pascal Kieslich, Parantu Shah, Thomas Mrowiec, Karin Tyroller
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Background Avelumab first‐line (1 L) maintenance is a standard of care for advanced urothelial carcinoma (aUC) based on the JAVELIN Bladder 100 phase 3 trial, which showed that avelumab 1 L maintenance + best supportive care (BSC) signific
Externí odkaz:
https://doaj.org/article/f5e67ed43d5e43618b9bcb2460270286
Autor:
Ana‐Marija Milenković‐Grišić, Nadia Terranova, Diane R. Mould, Yulia Vugmeyster, Thomas Mrowiec, Andreas Machl, Pascal Girard, Karthik Venkatakrishnan, Akash Khandelwal
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 1, Pp 143-153 (2024)
Abstract This analysis aimed to quantify tumor dynamics in patients receiving either bintrafusp alfa (BA) or pembrolizumab, by population pharmacokinetic (PK)‐pharmacodynamic modeling, and investigate clinical and molecular covariates describing th
Externí odkaz:
https://doaj.org/article/f72495eac4e94dfc80362557b409a4e6
Autor:
Hans Juergen Grote, Beatriz Pérez, Sharon Ruane, Lukas Ruff, Maximilian Alber, Annika F Fink, Roman Schulte-Sasse, Martin Bauw, Deepti Agrawal, Mariam Sadeq, Yae Ohata, Thomas Mrowiec
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/3ccf3f5395bf415188d21d861dfda261
Autor:
Frauke Wilm, Christian Ihling, Gábor Méhes, Luigi Terracciano, Chloé Puget, Robert Klopfleisch, Peter Schüffler, Marc Aubreville, Andreas Maier, Thomas Mrowiec, Katharina Breininger
Publikováno v:
Journal of Pathology Informatics, Vol 14, Iss , Pp 100301- (2023)
The success of immuno-oncology treatments promises long-term cancer remission for an increasing number of patients. The response to checkpoint inhibitor drugs has shown a correlation with the presence of immune cells in the tumor and tumor microenvir
Externí odkaz:
https://doaj.org/article/6ea89d013d5049edbf8ebf5def440677
Autor:
Jake Conway, Limin Yu, Yash Belhe, Suyog Jain, Hans Grote, Mary Lin, Benjamin Trotter, Darpan Sanghavi, Aslihan Gerhold-Ay, XiaoZhe Wang, Sergine Brutus, Thomas Mrowiec
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b535507f67f0afd07b924d3416f14123
https://doi.org/10.1136/jitc-2022-sitc2022.0554
https://doi.org/10.1136/jitc-2022-sitc2022.0554
Autor:
Thomas Mrowiec, Sharon Ruane, Simon Schallenberg, Gabriel Dernbach, Rumyana Todorova, Cornelius Böhm, Walter de Back, Blanca Pablos, Roman Schulte-Sasse, Ivana Trajanovska, Adelaida Creosteanu, Emil Barbuta, Marcus Otte, Christian Ihling, Hans Juergen Grote, Juergen Scheuenpflug, Viktor Matyas, Maximilian Alber, Frederick Klauschen
Publikováno v:
Cancer Research. 82:457-457
Background: Automated cell-level characterization of the tumor microenvironment (TME) at scale is key to data-driven immuno-oncology. Artificial intelligence (AI)-powered analysis of hematoxylin and eosin (H&E) images scales and has recently been tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8941b464ed1dc3d51b46227e4b5283ef
https://doi.org/10.1158/1538-7445.am2022-457
https://doi.org/10.1158/1538-7445.am2022-457
Autor:
Robin Liechti, Yervand Karapetyan, Stephanie Renaud-Tissot, Michelle Daniel, Sylvie Rusakiewicz, Nils Eling, Henoch S. Hong, Marie Morfouace, Bernd Bodenmiller, Jonas Windhager, Thomas Mrowiec, Daniel Schulz
Publikováno v:
Cancer Research. 81:2756-2756
Highly multiplexed imaging technologies are increasingly applied in biomedical research to identify underlying patterns of disease. As part of an IMI-funded project, the IMMUcan (Integrated immunoprofiling of large adaptive cancer patients cohorts) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2530bfcd83c45e7edc07959af8da2dc
https://doi.org/10.1158/1538-7445.am2021-2756
https://doi.org/10.1158/1538-7445.am2021-2756
Autor:
Aslihan Gerhold-Ay, Elena Svenson, Corinna M Wolf, Anja von Heydebreck, Glenn Beeman, P. Alexander Rolfe, Marcus Otte, Juergen Scheuenpflug, M. Ruisi, Ti Cai, Thomas Mrowiec, Parantu K. Shah, Hans Juergen Grote, Violeta Labarta-Beceiro
Publikováno v:
Journal of Clinical Oncology. 38:e21539-e21539
e21539 Background: Assessment of programmed death ligand-1 (PD-L1) protein expression using immunohistochemistry (IHC)-based tests is currently the only approved biomarker guiding treatment of non-small cell lung cancer (NSCLC) with checkpoint inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1871395067c3b5ae324480cb0077a92
https://doi.org/10.1200/jco.2020.38.15_suppl.e21539
https://doi.org/10.1200/jco.2020.38.15_suppl.e21539
Autor:
Matthias P. Mayer, Thomas Mrowiec, Daniel L. Minor, Steffen Frey, Blanche Schwappach, Kai Michelsen, Karl E. Duderstadt
Publikováno v:
Traffic. 7:903-916
Arginine (Arg)-based endoplasmic reticulum (ER) localization signals are sorting motifs involved in the quality control of multimeric membrane proteins. They are distinct from other ER localization signals like the C-terminal di-lysine [-K(X)KXX] sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::763c71c814e65b8d3a88e8fe0185fa75
https://doi.org/10.1111/j.1600-0854.2006.00430.x
https://doi.org/10.1111/j.1600-0854.2006.00430.x
Autor:
Blanche Schwappach, Thomas Mrowiec
Publikováno v:
GBM Annual Spring meeting Mosbach 2007. 2007
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f320069e93855bbcef73322e3b4dbf4d
https://doi.org/10.1240/sav_gbm_2007_m_001778
https://doi.org/10.1240/sav_gbm_2007_m_001778