Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Thomas Moore Morris"'
Autor:
Alenca Harrington, Thomas Moore-Morris
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
In heart disease patients, myocyte loss or malfunction invariably leads to fibrosis, involving the activation and accumulation of cardiac fibroblasts that deposit large amounts of extracellular matrix. Apart from the vital replacement fibrosis that f
Externí odkaz:
https://doaj.org/article/f6fe2629b15a40e1b0c763192c234f92
Autor:
Tui Neri, Emilye Hiriart, Patrick P. van Vliet, Emilie Faure, Russell A. Norris, Batoul Farhat, Bernd Jagla, Julie Lefrancois, Yukiko Sugi, Thomas Moore-Morris, Stéphane Zaffran, Randolph S. Faustino, Alexander C. Zambon, Jean-Pierre Desvignes, David Salgado, Robert A. Levine, Jose Luis de la Pompa, André Terzic, Sylvia M. Evans, Roger Markwald, Michel Pucéat
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
There are few human models that can recapitulate valve development in vitro. Here, the authors derive human pre-valvular endocardial cells (HPVCs) from iPSCs and show they can recapitulate early valvulogenesis, and patient derived HPVCs have features
Externí odkaz:
https://doaj.org/article/e45f606ce5c6400ca0225b4e0d2ad5be
Autor:
Laura Rolland, Alenca Harrington, Adèle Faucherre, Jourdano Mancilla Abaroa, Girisaran Gangatharan, Laurent Gamba, Dany Severac, Marine Pratlong, Thomas Moore-Morris, Chris Jopling
Publikováno v:
Journal of molecular cell biology
Journal of molecular cell biology, 2022, 14 (10), pp.mjac059. ⟨10.1093/jmcb/mjac059⟩
Journal of molecular cell biology, 2022, 14 (10), pp.mjac059. ⟨10.1093/jmcb/mjac059⟩
Understanding how certain animals are capable of regenerating their hearts will provide much needed insights into how this process can be induced in humans in order to reverse the damage caused by myocardial infarction. Currently, it is becoming incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc2000710366f0d9ea7c8ef09a5258a
https://hal.science/hal-03830878/file/mjac059.pdf
https://hal.science/hal-03830878/file/mjac059.pdf
Autor:
Chris Jopling, Laura Rolland, Laurent Gamba, Dany Severac, Alenca Harrington, Thomas Moore-Morris, Marine Pratlong, Adèle Faucherre, Girisaran Gangatharan
Understanding how certain animals are capable of regenerating their hearts will provide much needed insights into how this process can be induced in humans in order to reverse the damage caused by myocardial infarction. Currently, it is becoming incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786959fc1d42ab4eaf3617e72ad9ddb0
https://doi.org/10.1101/2021.10.25.465720
https://doi.org/10.1101/2021.10.25.465720
Autor:
Indroneal Banerjee, Jianlin Zhang, Thomas Moore-Morris, Emily Pfeiffer, Kyle S Buchholz, Ao Liu, Kunfu Ouyang, Matthew J Stroud, Larry Gerace, Sylvia M Evans, Andrew McCulloch, Ju Chen
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004114 (2014)
Recent interest has focused on the importance of the nucleus and associated nucleoskeleton in regulating changes in cardiac gene expression in response to biomechanical load. Mutations in genes encoding proteins of the inner nuclear membrane and nucl
Externí odkaz:
https://doaj.org/article/0ffa33f0b87146718f10ed4b4565896e
Autor:
Thomas Moore-Morris, Gilles Dilanian, N Mougeneot, Stéphane N. Hatem, N Suffee-Mosbah, Michel Pucéat
Publikováno v:
European Heart Journal. 40
Context and objectives Fibro-fatty infiltrations of the sub-epicardium is an important component of the atrial cardiomyopathy that paves the way of atrial fibrillation (AF). We previously reported that epicardium-derived cells (EPDCs) can be a source
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3fea4aebddd8bdec6e109e39faf6f18
https://doi.org/10.1093/eurheartj/ehz748.0190
https://doi.org/10.1093/eurheartj/ehz748.0190
Autor:
Thomas Moore-Morris, Michel Pucéat, Nadine Suffee, Nathalie Mougenot, Stéphane N. Hatem, Prince Pl, Myriam Berthet, Bernd Jagla, Gilles Dilanian, David-Alexandre Trégouët, Proukhnitzky J
Epicardium, the mesothelium covering the heart, is composed of multipotent cells and is reactivated following myocardial injury in adults. Herein, we provide evidence for activation of atrial epicardium in aged patients with diseased atria and in mur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674f1cddd53c7fcad4fea7aad46e1d46
Publikováno v:
Physiological reviews. 98(4)
The heart is the first organ to be functional in the fetus. Heart formation is a complex morphogenetic process regulated by both genetic and epigenetic mechanisms. Congenital heart diseases (CHD) are the most prominent congenital diseases. Genetics i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f000c9bb899afdefad9df2d00e5151
https://pubmed.ncbi.nlm.nih.gov/30156497
https://pubmed.ncbi.nlm.nih.gov/30156497
Autor:
Randolph S. Faustino, Thomas Moore-Morris, Tui Neri, Stéphane Zaffran, Emilye Hiriart, Robert A. Levine, Yukiko Sugi, Michel Pucéat, David Salgado, Andre Terzic, Emilie Faure, Julie Lefrancois, Alexander C. Zambon, Batoul Farhat, Roger R. Markwald, José Luis de la Pompa, Jean-Pierre Desvignes, Russell A. Norris, Sylvia M. Evans, Patrick van Vliet
Genetically modified mice have advanced our understanding of valve development and related pathologies. Yet, little is known regarding human valvulogenesis in health and diseases. Genuine humanin vitromodels that reproduce valvular (patho)biology are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2ae53ea58f0594946f5d04d88172e1
https://doi.org/10.1101/397422
https://doi.org/10.1101/397422
Autor:
Ju Chen, Yusu Gu, Paola Cattaneo, Thomas Moore-Morris, Tatiana Kisseleva, Nuno Guimarães-Camboa, Julius Bogomolovas, Lunfeng Zhang, Sylvia M. Evans, Michel Pucéat, Mercedes Ricote, Marta Cedenilla, Indroneal Banerjee, Nancy D. Dalton, Kirk L. Peterson
Publikováno v:
Circulation research, vol 122, iss 4
Circulation Research
Circulation Research, American Heart Association, 2018, 122 (4), pp.583-590
Circulation Research, 2018, 122 (4), pp.583-590
Repisalud
Instituto de Salud Carlos III (ISCIII)
Circulation Research
Circulation Research, American Heart Association, 2018, 122 (4), pp.583-590
Circulation Research, 2018, 122 (4), pp.583-590
Repisalud
Instituto de Salud Carlos III (ISCIII)
Myocardial infarction is a major cause of adult mortality worldwide. The origin(s) of cardiac fibroblasts that constitute the postinfarct scar remain controversial, in particular the potential contribution of bone marrow lineages to activated fibrobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9271704aba6bcd5a7c941fa025c8f193
https://escholarship.org/uc/item/0s40t2h3
https://escholarship.org/uc/item/0s40t2h3