Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Thomas Montavon"'
Autor:
Raphaël Pantier, Megan Brown, Sicheng Han, Katie Paton, Stephen Meek, Thomas Montavon, Nicholas Shukeir, Toni McHugh, David A. Kelly, Tino Hochepied, Claude Libert, Thomas Jenuwein, Tom Burdon, Adrian Bird
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Correlative evidence has suggested that the methyl-CpG-binding protein MeCP2 contributes to the formation of heterochromatin condensates via liquid-liquid phase separation. This interpretation has been reinforced by the observation that hete
Externí odkaz:
https://doaj.org/article/8624fe27fea0477cbeee8d7082173fcb
Autor:
Thomas Montavon, Nicholas Shukeir, Galina Erikson, Bettina Engist, Megumi Onishi-Seebacher, Devon Ryan, Yaarub Musa, Gerhard Mittler, Alexandra Graff Meyer, Christel Genoud, Thomas Jenuwein
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Histone H3K9 methylation (H3K9me) states define repressed chromatin in eukaryotic cells. Here the authors reveal complete loss of all H3K9me in mammalian cells through successive deletion of H3K9 methyltransferase genes that results in the dissolutio
Externí odkaz:
https://doaj.org/article/ffb762bd6b22494b91032351da989456
Autor:
Saskia Delpretti, Thomas Montavon, Marion Leleu, Elisabeth Joye, Athanasia Tzika, Michel Milinkovitch, Denis Duboule
Publikováno v:
Cell Reports, Vol 5, Iss 1, Pp 137-150 (2013)
Hox genes are required for the development of the intestinal cecum, a major organ of plant-eating species. We have analyzed the transcriptional regulation of Hoxd genes in cecal buds and show that they are controlled by a series of enhancers located
Externí odkaz:
https://doaj.org/article/259da3d7f6654202bbd1231d588a3117
Autor:
Marjorie Romon, Isabelle Soustre-Gacougnolle, Carine Schmitt, Mireille Perrin, Yannick Burdloff, Elodie Chevalier, Jérome Mutterer, Christophe Himber, Jérôme Zervudacki, Thomas Montavon, Aude Zimmermann, Taline Elmayan, Hervé Vaucheret, Patrice Dunoyer, Jean E Masson
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82652 (2013)
RNA silencing is a natural defence mechanism against viruses in plants, and transgenes expressing viral RNA-derived sequences were previously shown to confer silencing-based enhanced resistance against the cognate virus in several species. However, R
Externí odkaz:
https://doaj.org/article/aa9b7764f8214a198cb710deb169be97
Autor:
Raphaël Pantier, Megan Brown, Sicheng Han, Katie Paton, Stephen Meek, Thomas Montavon, Toni McHugh, David A. Kelly, Tino Hochepied, Claude Libert, Thomas Jenuwein, Tom Burdon, Adrian Bird
Correlative evidence has suggested that DNA methylation promotes the formation of transcriptionally silent heterochromatin. Accordingly, the methyl-CpG binding domain protein MeCP2 is often portrayed as a constituent of heterochromatin. This interpre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d69aa2cb100d0541ef4b5596d423395
https://doi.org/10.1101/2023.05.09.539985
https://doi.org/10.1101/2023.05.09.539985
Autor:
Dounia Djeghloul, Andrew Dimond, Holger Kramer, Karen Brown, Bhavik Patel, Yi-Fang Wang, Matthias E. Futschik, Chad Whilding, Alex Montoya, Nicolas Veland, Sherry Cheriyamkunnel, Thomas Montavon, Thomas Jenuwein, Matthias Merkenschlager, Amanda G. Fisher
Publikováno v:
Nature Structural and Molecular Biology
Recent studies have shown that repressive chromatin machinery, including DNA methyltransferases and polycomb repressor complexes, binds to chromosomes throughout mitosis and their depletion results in increased chromosome size. In the present study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801713bb3925b3124205b3360f17ce1c
https://hdl.handle.net/21.11116/0000-000D-12B4-321.11116/0000-000D-12B6-1
https://hdl.handle.net/21.11116/0000-000D-12B4-321.11116/0000-000D-12B6-1
Foxd3 controls heterochromatin‐mediated repression of repeat elements and 2‐cell state transcription
Autor:
Megumi Onishi-Seebacher, Thomas Montavon, Devon Ryan, Bettina Engist, Deepika Puri, Birgit Koschorz, Mamilla Soujanya
Publikováno v:
EMBO Reports
Repeat element transcription plays a vital role in early embryonic development. The expression of repeats such as MERVL characterises mouse embryos at the 2‐cell stage and defines a 2‐cell‐like cell (2CLC) population in a mouse embryonic stem c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1587162df4cc42cefaa91a2e76267120
http://europepmc.org/articles/PMC8647145
http://europepmc.org/articles/PMC8647145
Autor:
Alexandra Graff Meyer, Megumi Onishi-Seebacher, Thomas Jenuwein, Yaarub Musa, Thomas Montavon, Nicholas Shukeir, Devon Ryan, Bettina Engist, Galina Erikson, Christel Genoud, Gerhard Mittler
Publikováno v:
Nature Communications, vol. 12, no. 1
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Histone H3 lysine 9 (H3K9) methylation is a central epigenetic modification that defines heterochromatin from unicellular to multicellular organisms. In mammalian cells, H3K9 methylation can be catalyzed by at least six distinct SET domain enzymes: S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff0c66130ab546a8f27599b09bb60cf
https://doi.org/10.1038/s41467-021-24532-8
https://doi.org/10.1038/s41467-021-24532-8
Autor:
Justin S. Becker, Kenneth S. Zaret, Thomas Jenuwein, Tanya Jain, Thomas Montavon, Lihong Sheng, Roberto Bonasio, Jessica Mae Grindheim, Tao Peng, Simone Sidoli, Greg Donahue, Benjamin A. Garcia, Kai Tan, Kimberly R. Blahnik, Dario Nicetto
Publikováno v:
Science
Reversing chromatin dynamics for development Compacted chromatin regions, marked by trimethylation of histone H3 at position lysine 9 (H3K9me3), occur at highly repeated DNA sequences, helping to suppress recombination and gene expression. Because pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ef3215652259bcd33c57baa3aa707d
https://doi.org/10.1126/science.aau0583
https://doi.org/10.1126/science.aau0583
Autor:
Philippe Hammann, Sébastien Pfeffer, Mathieu Lefèvre, Erika Girardi, Johana Chicher, Morgane Baldaccini, Mélanie Messmer, Thomas Montavon, Béatrice Chane-Woon-Ming
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2021, 17 (5), pp.e1009549. ⟨10.1371/journal.ppat.1009549⟩
PLOS Pathogens
bioRxiv
PLoS Pathogens, 2021, 17 (5), pp.e1009549. ⟨10.1371/journal.ppat.1009549⟩
PLoS Pathogens, Vol 17, Iss 5, p e1009549 (2021)
PLoS Pathogens, Public Library of Science, 2021, 17 (5), pp.e1009549. ⟨10.1371/journal.ppat.1009549⟩
PLOS Pathogens
bioRxiv
PLoS Pathogens, 2021, 17 (5), pp.e1009549. ⟨10.1371/journal.ppat.1009549⟩
PLoS Pathogens, Vol 17, Iss 5, p e1009549 (2021)
The antiviral innate immune response mainly involves type I interferon (IFN) in mammalian cells. The contribution of the RNA silencing machinery remains to be established, but several recent studies indicate that the ribonuclease DICER can generate v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85ba227846bf60188097ab170be8f08
https://hal.archives-ouvertes.fr/hal-03328063/document
https://hal.archives-ouvertes.fr/hal-03328063/document