Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Thomas Meergans"'
Autor:
Sylvia Knapp, Sebastian Bunk, Kurt Derfler, Julia Hoffmann, Thomas M. Stulnig, Sonja von Aulock, Thomas Meergans, Karin Stich, Susanne Deininger, Bianca Doninger, Stefanie Sigel
Publikováno v:
European Journal of Immunology. 42:2983-2989
Plasma lipoproteins such as LDL (low-density lipoprotein) are important therapeutic targets as they play a crucial role in macrophage biology and metabolic disorders. The impact of lipoprotein profiles on host defense pathways against Gram-positive b
Autor:
Dieter Hassler, Markus Mueller, Carolin Rauter, Thomas Hartung, Sabine Zeller, Thomas Meergans, Isabel Diterich
Publikováno v:
Clinical and Vaccine Immunology. 12:910-917
Many approaches were made in recent years to establish urine PCR as a diagnostic tool for Lyme borreliosis, but results are contradictory. In the present study, a standardized protocol spiking urine from healthy donors with a defined amount of whole
Publikováno v:
Biochemical Journal. 349:135-140
Proteolytic activation of caspases is a key step in the process of apoptosis. According to their primary structure, caspases can be divided into a group with a long prodomain and a group with a short prodomain. Whereas long prodomains play a role in
Autor:
Albrecht Wendel, Hannes Hentze, Paul-Georg Germann, Gerald Künstle, Gisa Tiegs, Thomas Meergans
Publikováno v:
Hepatology. 30:1241-1251
Several models of tumor necrosis factor (TNF)/TNF-receptor 1 (TNF-R1)-dependent liver injury in mice were investigated with respect to caspase-3-like protease activation representing a pivotal mechanism of apoptotic cell death. Injection of TNF or T-
Publikováno v:
Biochemical Journal. 337:319-327
Characteristic steps in the course of cellular apoptosis are the induction of chromatin condensation and cleavage of the DNA, leading to the formation of oligomers of nucleosomes. Since the H1 histones represent functional elements that are essential
Publikováno v:
European Journal of Biochemistry. 256:436-446
In man, the H1 class of histones consists of seven different isoforms, termed H1.1-H1.5, H1t and H1o. Analysis of the promoters of the respective genes reveals that all seven H1 gene promoters share conserved sequence elements: a TATA box at around p
Publikováno v:
Gene. 184:141-148
The H1 histone family in mammals contains at least seven subtypes. In the past we have isolated six of the seven genes encoding these isoforms. To complete the set of the human H1 histone genes, we have designed two PCR primers deduced from a partial
Autor:
Stefanie, Sigel, Sebastian, Bunk, Thomas, Meergans, Bianca, Doninger, Karin, Stich, Thomas, Stulnig, Kurt, Derfler, Julia, Hoffmann, Susanne, Deininger, Sonja, von Aulock, Sylvia, Knapp
Publikováno v:
European journal of immunology. 42(11)
Plasma lipoproteins such as LDL (low-density lipoprotein) are important therapeutic targets as they play a crucial role in macrophage biology and metabolic disorders. The impact of lipoprotein profiles on host defense pathways against Gram-positive b
Publikováno v:
Biochemical and biophysical research communications. 325(3)
In vitro non-natural amino acid mutagenesis requires aminoacyl-charged suppressor transfer RNAs which read an internal stop codon. For the synthesis of aminoacyl-tRNAs loaded with non-natural amino acids, T4 RNA ligase is used to ligate a chemically
Publikováno v:
DNA and cell biology. 16(9)
Five main type H1 histones have been described in man (H1.1-H1.5) in addition to the testis specific type H1t and the replacement subtype H1 degrees, which is found mainly in highly differentiated cells. We have isolated this whole complement of H1 g