Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Thomas Mcavoy"'
Publikováno v:
Insects, Vol 11, Iss 8, p 515 (2020)
With the recent introduction of the non-native spotted lanternfly (Lycorma delicatula) to the USA, research and concern regarding this insect is increasing. Though L. delicatula is able to feed on many different plant species, its preference for the
Externí odkaz:
https://doaj.org/article/6a1b8530bc774ea3baa1166282d4561a
Autor:
Omar F Laterza, Thomas McAvoy, Kapil Mayawala, Claire Li, Michael E. Lassman, Derek L Chappell, Scott K. Pruitt, Amy Cheng, Dinesh P. de Alwis, Aubrey Stoch
Publikováno v:
Clinical Pharmacology & Therapeutics. 109:1575-1582
Development of monoclonal antibodies (mAbs) targeting immune-checkpoint receptors (IMRs) for the treatment of cancer is one of the most active areas of investment in the biopharmaceutical industry. A key decision in the clinical development of anti-I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f538f23c11d92542fc99cf2dc0e39c
https://doi.org/10.1002/cpt.2129
https://doi.org/10.1002/cpt.2129
Autor:
Wenping, Li, Yuchuan, Wang, Talakad G, Lohith, Zhizhen, Zeng, Ling, Tong, Robert, Mazzola, Kerry, Riffel, Patricia, Miller, Mona, Purcell, Marie, Holahan, Hyking, Haley, Liza, Gantert, David, Hesk, Sumei, Ren, John, Morrow, Jason, Uslaner, Arie, Struyk, Jenny Miu-Chun, Wai, Michael T, Rudd, David M, Tellers, Thomas, McAvoy, Guy, Bormans, Michel, Koole, Koen, Van Laere, Kim, Serdons, Jan, de Hoon, Ruben, Declercq, Inge, De Lepeleire, Maria B, Pascual, Paolo, Zanotti-Fregonara, Meixiang, Yu, Victoria, Arbones, Joseph C, Masdeu, Amy, Cheng, Azher, Hussain, Tjerk, Bueters, Matt S, Anderson, Eric D, Hostetler, Anthony S, Basile
Publikováno v:
Science translational medicine. 14(627)
Positron emission tomography (PET) ligands play an important role in the development of therapeutics by serving as target engagement or pharmacodynamic biomarkers. Here, we describe the discovery and translation of the PET tracer [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4a48387c373777e91d8509feb8c9c29
https://pubmed.ncbi.nlm.nih.gov/35020407
https://pubmed.ncbi.nlm.nih.gov/35020407
Autor:
Wenping Li, Yuchuan Wang, Talakad G. Lohith, Zhizhen Zeng, Ling Tong, Robert Mazzola, Kerry Riffel, Patricia Miller, Mona Purcell, Marie Holahan, Hyking Haley, Liza Gantert, David Hesk, Sumei Ren, John Morrow, Jason Uslaner, Arie Struyk, Jenny Miu-Chun Wai, Michael T. Rudd, David M. Tellers, Thomas McAvoy, Guy Bormans, Michel Koole, Koen Van Laere, Kim Serdons, Jan de Hoon, Ruben Declercq, Inge De Lepeleire, Maria B. Pascual, Paolo Zanotti-Fregonara, Meixiang Yu, Victoria Arbones, Joseph C. Masdeu, Amy Cheng, Azher Hussain, Tjerk Bueters, Matt S. Anderson, Eric D. Hostetler, Anthony S. Basile
Positron emission tomography (PET) ligands play an important role in the development of therapeutics by serving as target engagement or pharmacodynamic biomarkers. Here, we describe the discovery and translation of the PET tracer [11C]MK-6884 from rh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e44197a5317a5a2a9f28fb0766d601b
https://lirias.kuleuven.be/handle/20.500.12942/688229
https://lirias.kuleuven.be/handle/20.500.12942/688229
Autor:
Xuemei X. Zhao, Michael E. Lassman, Thomas McAvoy, Anita Y. Lee, Derek L Chappell, Omar F Laterza
Publikováno v:
Clinica Chimica Acta. 459:155-161
Reports of mass spectrometry based assays for peptides and proteins have become increasingly common in the literature. The growing interest of mass spectrometry for use in clinical laboratories has been primarily driven by the inherent selectivity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732e6ddd15465e86e2dbd947dcd73978
https://doi.org/10.1016/j.cca.2016.05.027
https://doi.org/10.1016/j.cca.2016.05.027
Autor:
Anita Yh Lee, Vinita Gupta, Thomas McAvoy, Omar F Laterza, Derek L Chappell, Michael E. Lassman
Publikováno v:
Bioanalysis. 8:1557-1564
Background: For quantitative immunoaffinity IA-LC–MS, the utility of antibodies has been demonstrated many times but the utility of aptamers as affinity reagents is unproven. Methods: Immunoaffinity reagents including a monoclonal antibody and an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e48c9b543aa058a68e1cd74cc5da7c3
https://doi.org/10.4155/bio-2016-0046
https://doi.org/10.4155/bio-2016-0046
Autor:
Thomas McAvoy
Publikováno v:
International Journal of Archaeology. 9:34
In the same issue of Nature that the radiocarbon dating results for the Shroud of Turin were published, Phillips hypothesized that neutron radiation could have altered the reported dates. In addition to making the Shroud appear younger than its true
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ade74138d8e87b7e8df92b641812d298
https://doi.org/10.11648/j.ija.20210902.11
https://doi.org/10.11648/j.ija.20210902.11
Autor:
Punam Sandhu, Joseph L. Duffy, Maria S. Michener, Sean M. Smith, Joan D. Ellis, Mary J. Savage, Ernest J. McEachern, Chandni Valiathan, Brittany Walker, Jeanine E. Ballard, Arie Struyk, David J. Vocadlo, Junghoon Lee, Dawn Toolan, Thomas McAvoy, Daniel P. Dreyer, Nicole Trainor, Jacob Marcus
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed7b11ee409914010230b3cf244ada5d
https://doi.org/10.1016/j.jalz.2016.06.2125
https://doi.org/10.1016/j.jalz.2016.06.2125
Autor:
Achilles Alon, Justin Dennie, Omar F Laterza, Michael E. Lassman, Thomas McAvoy, David G. McLaren, Derek L Chappell, Sudha S. Shankar, Helene L. Cardasis, Gino Salituro, Manu Chakravarthy, Xiaofang Li, Jennifer E Lambert, Elizabeth J. Parks
Publikováno v:
Bioanalysis. 8(12)
Aim: A traditional oral fatty acid challenge assesses absorption of triacylglycerol (TG) into the periphery through the intestines, but cannot distinguish the composition or source of fatty acid in the TG. Stable isotope-labeled tracers combined with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65284536b5c9da6a6248a1d0debec69a
https://pubmed.ncbi.nlm.nih.gov/27225968
https://pubmed.ncbi.nlm.nih.gov/27225968
Publikováno v:
Bioanalysis. 4:2843-2850
Background: Renin catalyzes the conversion of angiotensinogen to angiotensin I (Ang I), the first and rate-limiting step in the renin–angiotensin–aldosterone system. Plasma renin activity (PRA) is an important target engagement biomarker in the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53b21a0aa508d617e74dc02ea6c9a08
https://doi.org/10.4155/bio.12.268
https://doi.org/10.4155/bio.12.268