Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Thomas McKee"'
Autor:
Bart Boersma, Viola Puddinu, Arnaud Huard, Sébastien Fauteux-Daniel, Pratyaksha Wirapati, Sofia Guedri, Jean-Christophe Tille, Thomas McKee, Mikael Pittet, Gaby Palmer, Carole Bourquin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Inflammation plays a pivotal role in cancer development, with chronic inflammation promoting tumor progression and treatment resistance, whereas acute inflammatory responses contribute to protective anti-tumor immunity. Gasdermin D (GSDMD) mediates t
Externí odkaz:
https://doaj.org/article/f4b80242743a430885ba5c660f5b5289
Autor:
Vassilis Genoud, Valérie Dutoit, Nhu-Nam Tran Thang, Andrew Janowczyk, Thomas McKee, Yves Chalandon, Petros Tsantoulis, Pierre-Yves Dietrich
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/9ee8d1413eab405f8161609c3ac50536
Autor:
George M. Ramzy, Maxim Norkin, Thibaud Koessler, Lionel Voirol, Mathieu Tihy, Dina Hany, Thomas McKee, Frédéric Ris, Nicolas Buchs, Mylène Docquier, Christian Toso, Laura Rubbia-Brandt, Gaetan Bakalli, Stéphane Guerrier, Joerg Huelsken, Patrycja Nowak-Sliwinska
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background We propose a new approach for designing personalized treatment for colorectal cancer (CRC) patients, by combining ex vivo organoid efficacy testing with mathematical modeling of the results. Methods The validated phenotypic approa
Externí odkaz:
https://doaj.org/article/60bf5c4478c549e8812684c5f9a09d4e
Autor:
Claudia Corrò, Nicolas C. Buchs, Matthieu Tihy, André Durham-Faivre, Philippe Bichard, Jean-Louis Frossard, Giacomo Puppa, Thomas McKee, Arnaud Roth, Thomas Zilli, Christelle Trembleau, Mariagrazia Di Marco, Valérie Dutoit, Pierre-Yves Dietrich, Frédéric Ris, Thibaud Koessler
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Reshaping the tumor microenvironment by novel immunotherapies represents a key strategy to improve cancer treatment. Nevertheless, responsiveness to these treatments is often correlated with the extent of T cell infiltration at th
Externí odkaz:
https://doaj.org/article/d7cd6151137d4ba7adddbcf2d6d73b80
Autor:
Giacomo Puppa, Inti Zlobec, Frederic Ris, Simone Benhamou, Thomas McKee, Valeria Viassolo, Laura Rubbia-Brandt, Evelyne Fournier, Thomas Zilli, Pierre Olivier Chappuis, Elisabetta Rapiti
Publikováno v:
BMJ Open, Vol 12, Iss 8 (2022)
Purpose Colorectal cancer (CRC) is the third leading cause of cancer death worldwide. Variability between patients in prognosis and treatment response is partially explained by traditional clinicopathological factors. We established a large populatio
Externí odkaz:
https://doaj.org/article/fb1fe6c967684768bdfc30379f8916e0
Autor:
Holger Moch, Gieri Cathomas, Milo Frattini, Wolfram Jochum, Erik Vassella, Laurence de Leval, Joachim Diebold, Christian Britschgi, Thomas McKee, Lukas Bubendorf
Publikováno v:
healthbook TIMES. Oncology Hematology, Vol 1, Iss 7, Pp 14-21 (2021)
In May 2020, larotrectinib (Vitrakvi®) was approved as the first tumor-agnostic agent in Switzerland for the treatment of adult and pediatric patients with solid tumors that have a neurotrophic tyrosine receptor kinase (NTRK) gene fusion. While in c
Externí odkaz:
https://doaj.org/article/cd0f6a5afccc4310b9147d52ed3cf998
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Immuno-oncology is an ever growing field that has seen important progress across the spectrum of cancers. Responses can be deep and durable. However, as only a minority of patients respond to checkpoint inhibition, predictive biomarkers are needed. C
Externí odkaz:
https://doaj.org/article/1833d4a3e885445c8ab06cec75a4258e
Autor:
Denis Migliorini, Nicolas Mach, Diego Aguiar, Rémi Vernet, Basile Nicolas Landis, Minerva Becker, Thomas McKee, Valérie Dutoit, Pierre-Yves Dietrich
Publikováno v:
OncoImmunology, Vol 6, Iss 8 (2017)
Chordoma is a rare tumor of notochordal origin, currently principally treated by surgery and/or irradiation. Here, we describe the clinical outcome of 3 consecutive patients with metastatic and locally advanced chordoma, treated with different immuno
Externí odkaz:
https://doaj.org/article/15ba3ae834f14e8593c636f763cba911
Autor:
Bertrand Huard, Nathalie Sturm, Thomas Matthes, Alexandar Tzankov, Pascal Schneider, Mary Callanan, Martin Dyer, Christian Righini, Christian Villiers, Sebastien Moret, Sebastien Tabruyn, Jean Francois Mayol, Thomas McKee, Benoit Manfroi
Healthy B-cells are CXCL-8 negative.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc39ec1e07009a8d37483c4475cd97c
https://doi.org/10.1158/0008-5472.22415973
https://doi.org/10.1158/0008-5472.22415973
Autor:
Bertrand Huard, Nathalie Sturm, Thomas Matthes, Alexandar Tzankov, Pascal Schneider, Mary Callanan, Martin Dyer, Christian Righini, Christian Villiers, Sebastien Moret, Sebastien Tabruyn, Jean Francois Mayol, Thomas McKee, Benoit Manfroi
Tumor-infiltrating neutrophils have been implicated in malignant development and progression, but mechanisms are ill defined. Neutrophils produce a proliferation-inducing ligand APRIL/TNFSF13, a factor that promotes development of tumors from diverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c6e1fd348b9caf50afdc3181078b68
https://doi.org/10.1158/0008-5472.c.6509433.v1
https://doi.org/10.1158/0008-5472.c.6509433.v1