Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Thomas McCreery"'
Autor:
Thomas McCreery, Robert H. Sweitzer, Terry O. Matsunaga, Rachel M. Quigley, Patricia A. Schumann, Jonathan P. Christiansen, Jonathan R. Lindner, Evan C. Unger
Publikováno v:
Investigative Radiology. 37:587-593
Rationale and Objectives. New targeted microbubbles directed to the GPIIb IIIa receptor have been developed. The objective was to determine whether targeting microbubbles to clots would enhance ultrasound imaging. Systematic studies were designed to
Autor:
Zhenguo Han, Thomas McCreery, Elizabeth G. Nabel, Peng Li, Mani A. Vannan, Bettina Kuersten, Sanjay Rajagopalan, Evan C. Unger
Publikováno v:
Journal of the American Society of Echocardiography. 15:214-218
We tested the hypothesis that targeted disruption of cationic microbubble-linked plasmid DNA, using diagnostic ultrasound, may aid transfection of large animal myocardium. Plasmid DNA encoding for CAT (pCAT, chloramphenicol acetyltransferase) was bou
Publikováno v:
Progress in Cardiovascular Diseases. 44:45-54
Ultrasound contrast agents (microbubbles) lower the threshold for cavitation by ultrasound energy. Ultrasound microbubbles may be used as cavitation nuclei for drug and gene delivery. By tailoring the physical properties of microbubbles and coating m
Autor:
Catherine Metzger-Rose, Terrence R. Barrette, Thomas McCreery, Elizabeth A. Krupinski, Evan C. Unger, Michael R. Baker, William H. Wright
Publikováno v:
Journal of Ultrasound in Medicine. 16:317-324
The purpose of this study was to determine if the sonographic contrast agent MRX-115 could improve the accuracy of Doppler ultrasonographic diagnosis of testicular ischemia. Testicular duplex ultrasonography was performed on six dogs before and after
Publikováno v:
Academic radiology. 9
We have developed a novel thrombus-specific ultrasound (US) contrast agent, MRX-408. MRX-408 has been shown to enhance thrombi in the left ventricular apex, left atrial appendage, peripheral veins, and peripheral arteries (1). This enhancement has be
Autor:
Terry O. Matsunaga, Rachel M. Quigley, Thomas McCreery, Evan C. Unger, Patricia A. Schumann, Robert H. Sweitzer
Publikováno v:
European journal of radiology. 42(2)
Microbubbles, currently used as contrast agents have potential therapeutic applications. Microbubbles, upon insonation of sufficiently intense ultrasound will cavitate. Cavitation with microbubbles can be used to dissolve blood clots or deliver drugs
Publikováno v:
Echocardiography (Mount Kisco, N.Y.). 18(4)
With the human genome product and continuing advances in molecular biology many therapeutic genes have been discovered. In the cardiovascular system, gene therapy has the potential to improve myocardial vascularization and ameliorate congestive heart
Publikováno v:
Investigative radiology. 33(12)
Paclitaxel-carrying lipospheres (MRX-552) were developed and evaluated as a new ultrasound contrast agent for chemotherapeutic drug delivery.Paclitaxel was suspended in soybean oil and added to an aqueous suspension of phospholipids in vials. The hea