Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Thomas Mancini"'
Autor:
Danielle J. McCullough, Nouaying Kue, Thomas Mancini, Alexander Vang, Richard T. Clements, Gaurav Choudhary
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary hypertension is associated with pronounced exercise intolerance (decreased V ċ O 2 max) that can significantly impact quality of life. The cause of exercise intolerance in pulmonary hypertension remains unclear. Mitochondrial supercomplexe
Externí odkaz:
https://doaj.org/article/cba774dd40ca4136a9cc616ff71451f7
Autor:
Iuliia Polina, Alexander Vang, Edward Hawrot, Denielli da Silva Gonçalves Bos, Thomas Mancini, Peng Zhang, Michael W. Cypress, Richard T. Clements, Ulrike Mende, Alan R. Morrison, Gaurav Choudhary, Ana Fernandez-Nicolas, Jin O-Uchi, Bong Sook Jhun
Publikováno v:
JCI Insight
Right ventricular (RV) fibrosis is a key feature of maladaptive RV hypertrophy and dysfunction and is associated with poor outcomes in pulmonary hypertension (PH). However, mechanisms and therapeutic strategies to mitigate RV fibrosis remain unrealiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136577afa14fa00328d64161ef35408e
http://europepmc.org/articles/PMC8262476
http://europepmc.org/articles/PMC8262476
Autor:
Wenzhuo Ma, Alexander Vang, Scarlett Huck, Clarissa C. Muller, Thomas Mancini, Preston Nicely, Peng Zhang, Gaurav Choudhary, Richard T. Clements
Publikováno v:
Biophysical Journal. 121:507a-508a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d396fbe7eadc14453ac5b3d9e6384f35
https://doi.org/10.1016/j.bpj.2021.11.222
https://doi.org/10.1016/j.bpj.2021.11.222
Autor:
Bong Sook Jhun, Michael W. Cypress, Ana Fernandez-Nicolas, Richard T. Clements, Alexander Vang, Jin O-Uchi, Thomas Mancini, Hana Zhou, Gaurav Choudhary
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38f7a4152b44748d98c81b9b0269346c
https://doi.org/10.1096/fasebj.2021.35.s1.04274
https://doi.org/10.1096/fasebj.2021.35.s1.04274
Autor:
Peng Zhang, Ana Fernandez Nicolas, Gaurav Choudhary, Alexander Vang, Richard T. Clements, Thomas Mancini, Denielli da Silva Goncalves Bos
Publikováno v:
Circulation. 142
Introduction: Pulmonary arterial hypertension (PAH) is characterized by severe pulmonary vascular remodeling. Transition of endothelial cells (EC) to mesenchymal cells (EndMT) contributes to vascular remodeling; however, the role of EndMT and underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d9d84bd1778aec21c7274cb656f7cef
https://doi.org/10.1161/circ.142.suppl_3.17072
https://doi.org/10.1161/circ.142.suppl_3.17072
Autor:
Owen P. Leary, Ana Fernandez Nicolas, Richard E. Gilbert, Thomas Mancini, Alexander Vang, Reza Avazmohammadi, Denielli da Silva Goncalves Bos, Gaurav Choudhary, Dana M. Leichter, Mohsen Nowruzpour
Publikováno v:
Circulation. 142
Introduction: Right Ventricular (RV) dysfunction in pulmonary arterial hypertension (PAH) is the major cause of mortality. Myocardial architecture determines the basis of heart function and can be assessed by generalized Q-space imaging by MRI (GQI),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fd74c78cc431b239e57adc02ce3605c
https://doi.org/10.1161/circ.142.suppl_3.17254
https://doi.org/10.1161/circ.142.suppl_3.17254
Autor:
Alexander Vang, Danielle J. McCullough, Nouaying Kue, Richard T. Clements, Gaurav Choudhary, Thomas Mancini
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary Circulation
Pulmonary Circulation
Pulmonary hypertension is associated with pronounced exercise intolerance (decreased V ċ O 2 max) that can significantly impact quality of life. The cause of exercise intolerance in pulmonary hypertension remains unclear. Mitochondrial supercomplexe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621df4f2ef872ec3533cc5e132eb7d61
https://doaj.org/article/cba774dd40ca4136a9cc616ff71451f7
https://doaj.org/article/cba774dd40ca4136a9cc616ff71451f7
Autor:
Alexander Vang, D. da Silva Goncalves Bos, Gaurav Choudhary, Thomas Mancini, Peng Zhang, A. Fernandez Nicolas, Richard T. Clements
Publikováno v:
C51. ALL ABOUT ENDOTHELIUM: CELLULAR AND MOLECULAR MECHANISMS AND EMERGING TREATMENT OPTIONS IN PULMONARY HYPERTENSION AND ACUTE LUNG INJURY.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8322d0a370a94f293212ddd7b69f239a
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5390
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5390
Autor:
Thomas Mancini, Gaurav Choudhary, N. Getachew, D. da Silva Goncalves Bos, Alexander Vang, Richard J. Gilbert, Dana M. Leichter, Owen P. Leary, A. Fernandez Nicolas
Publikováno v:
A57. PULMONARY VASCULAR DISEASES AND RV FUNCTIONS: NOVEL SIGNALLING MECHANISMS, EXCITING MODELS AND EMERGING TREATMENT OPTIONS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73ab15e1c351590caf503b6472c15d10
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2104
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2104
Autor:
Ayed Allawzi, Alexander Vang, Bong Sook Jhun, Richard T. Clements, Jin O-Uchi, Nouaying R. Kue, Suzy A.A. Comhair, Thomas Mancini, Serpil C. Erzurum, Amy K. Landi, Gaurav Choudhary, Dmitry Terentyev
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 58:658-667
Hyperproliferative endothelial cells (ECs) play an important role in the pathogenesis of pulmonary arterial hypertension (PAH). Anoctamin (Ano)-1, a calcium-activated chloride channel, can regulate cell proliferation and cell cycle in multiple cell t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef04ecf73b57e414a89ec45b2a0f7691
https://doi.org/10.1165/rcmb.2016-0344oc
https://doi.org/10.1165/rcmb.2016-0344oc