Výsledky vyhledávání - "Thomas M. Tolbert"

Akademický článek

Selective Continuous Positive Airway Pressure Withdrawal With Supplemental Oxygen During Slow-Wave Sleep as a Method of Dissociating Sleep Fragmentation and Intermittent Hypoxemia-Related Sleep Disruption in Obstructive Sleep Apnea

Autor: Anna E. Mullins, Ankit Parekh, Korey Kam, Bresne Castillo, Zachary J. Roberts, Ahmad Fakhoury, Daphne I. Valencia, Reagan Schoenholz, Thomas M. Tolbert, Jason Z. Bronstein, Anne M. Mooney, Omar E. Burschtin, David M. Rapoport, Indu Ayappa, Andrew W. Varga

Publikováno v: Frontiers in Physiology, Vol 12 (2021)

Obstructive sleep apnea (OSA) is considered to impair memory processing and increase the expression of amyloid-β (Aβ) and risk for Alzheimer’s disease (AD). Given the evidence that slow-wave sleep (SWS) is important in both memory and Aβ metabol

Externí odkaz: https://doaj.org/article/b00fd74d7d704889a1ecdf5838c87716

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Night-to-night reliability and agreement of obstructive sleep apnea pathophysiologic mechanisms estimated with phenotyping using polysomnography in cognitively normal elderly participants

Autor: Thomas M Tolbert, Reagan L Schoenholz, Ankit Parekh, Asem Berkalieva, Ricardo S Osorio, Indu Ayappa, David M Rapoport

Publikováno v: SLEEP.

Study Objectives Phenotyping using polysomnography (PUP) is an algorithmic method to quantify physiologic mechanisms underlying obstructive sleep apnea (OSA): loop gain (LG1), arousal threshold (ArTH), and upper airway collapsibility (Vpassive) and m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::545c5279406158a7985c99ce97394946
https://doi.org/10.1093/sleep/zsad058

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Endotyping Sleep Apnea One Breath at a Time: An Automated Approach for Separating Obstructive from Central Sleep-disordered Breathing

Autor: Jaime Ramos-Cejudo, Anne M Mooney, David M. Rapoport, Simon-Dominik Herkenrath, Winfried Randerath, Ricardo S. Osorio, Ankit Parekh, Thomas M. Tolbert, Marcel Treml, Indu Ayappa

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 204:1452-1462

Rationale: Determining whether an individual has obstructive or central sleep apnea is fundamental to selecting the appropriate treatment. Objectives: Here we derive an automated breath-by-breath p...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28af37ae422ef335e9abbe0586c7d3b
https://doi.org/10.1164/rccm.202011-4055oc

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Quantification of airway conductance from noninvasive ventilatory drive in patients with sleep apnea

Autor: Indu Ayappa, David M. Rapoport, Ankit Parekh, Thomas M. Tolbert, Anne M Mooney, Scott A. Sands

Publikováno v: J Appl Physiol (1985)

Upper airway conductance, the ratio of inspiratory airflow to inspiratory effort, quantifies the degree of airway obstruction in hypopneas observed in sleep apnea. We evaluated the ratio of ventilation to noninvasive ventilatory drive as a surrogate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07118f73c74cdd141a8d6e8f618d5ad2
https://doi.org/10.1152/japplphysiol.00387.2021

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Cardiac index is associated with oxygenation in COVID‐19 acute respiratory distress syndrome

Autor: Hooman D. Poor, Alexandra S. Reynolds, Kevin M Rurak, Corey E. Ventetuolo, Ali Mustafa, Thomas M. Tolbert, Elena Colicino, Kaitlin Reilly, Daniel Howell, Alison Lee

Publikováno v: Pulmonary Circulation, Vol 11 (2021)
Pulmonary Circulation

Eleven participants with COVID-19 acute respiratory distress syndrome requiring mechanical ventilation underwent pulmonary artery catheterization for clinical indications. Clinical interventions or events concurrent with hemodynamic were recorded. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395f23b181fc785fbf6fda03bf418e97
https://doi.org/10.1177/20458940211019626

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COVID‐19 critical illness pathophysiology driven by diffuse pulmonary thrombi and pulmonary endothelial dysfunction responsive to thrombolysis

Autor: Glen Chun, Thomas M. Tolbert, Jeffrey W. Olin, Neha S. Dangayach, Corey E. Ventetuolo, Amanda Zeidman, Charles A. Powell, Hooman D. Poor, Roopa Kohli-Seth, Gregory Serrao

Publikováno v: Clinical and Translational Medicine
medRxiv
article-version (status) pre
article-version (number) 1
Clinical and Translational Medicine, Vol 10, Iss 2, Pp n/a-n/a (2020)

Patients with severe COVID‐19 disease have been characterized as having the acute respiratory distress syndrome (ARDS). Critically ill COVID‐19 patients have relatively well‐preserved lung mechanics despite severe gas exchange abnormalities, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6274036aed874768382b2ba69e63b695
https://doi.org/10.1002/ctm2.44

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