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pro vyhledávání: '"Thomas M. T. Jensen"'
Autor:
Per Jemth, Linda M. Haugaard-Kedström, Kristian Strømgaard, Andreas Karlsson, Christian R. O. Bartling, Thomas M T Jensen, Emma Åberg
Publikováno v:
ACS Chemical Biology
Jensen, T M T, Bartling, C R O, Karlsson, O A, Åberg, E, Haugaard-Kedström, L M, Strømgaard, K & Jemth, P 2021, ' Molecular Details of a Coupled Binding and Folding Reaction between the Amyloid Precursor Protein and a Folded Domain ', ACS chemical biology, vol. 16, no. 7, pp. 1191-1200 . https://doi.org/10.1021/acschembio.1c00176
Jensen, T M T, Bartling, C R O, Karlsson, O A, Åberg, E, Haugaard-Kedström, L M, Strømgaard, K & Jemth, P 2021, ' Molecular Details of a Coupled Binding and Folding Reaction between the Amyloid Precursor Protein and a Folded Domain ', ACS chemical biology, vol. 16, no. 7, pp. 1191-1200 . https://doi.org/10.1021/acschembio.1c00176
Intrinsically disordered regions in proteins often function as binding motifs in protein-protein interactions. The mechanistic aspects and molecular details of such coupled binding and folding reactions, which involve formation of multiple noncovalen
Autor:
Jan Daberger, Louise S. Clemmensen, Kristian Strømgaard, Eduardo Felipe Alves Fernandes, Flor Abalde-Gil, Weontae Lee, Pascale Zimmermann, Raphael Leblanc, Petra Hamerlik, Renaud Vincentelli, Jeanette Hammer Andersen, Zeyu Jin, Vita Sereikaite, Bianca Wind, Marte Albrigtsen, Thomas M. T. Jensen, Maria Vistrup-Parry, Antonio L. Egea-Jimenez, Diana Aguilar-Morante, Linda M. Haugaard-Kedström, Kamilla E. Jensen, Ylva Ivarsson
Publikováno v:
Haugaard-Kedstrom, L M, Clemmensen, L S, Sereikaite, V, Jin, Z, Fernandes, E F A, Wind, B, Abalde-Gil, F, Daberger, J, Vistrup-Parry, M, Aguilar-Morante, D, Leblanc, R, Egea-Jimenez, A L, Albrigtsen, M, Jensen, K E, Jensen, T M T, Ivarsson, Y, Vincentelli, R, Hamerlik, P, Andersen, J H, Zimmermann, P, Lee, W & Stromgaard, K 2021, ' A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma ', Journal of Medicinal Chemistry, vol. 64, no. 3, pp. 1423-1434 . https://doi.org/10.1021/acs.jmedchem.0c00382
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (3), pp.1423-1434. ⟨10.1021/acs.jmedchem.0c00382⟩
Journal of Medicinal Chemistry, 2021, 64 (3), pp.1423-1434. ⟨10.1021/acs.jmedchem.0c00382⟩
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (3), pp.1423-1434. ⟨10.1021/acs.jmedchem.0c00382⟩
Journal of Medicinal Chemistry, 2021, 64 (3), pp.1423-1434. ⟨10.1021/acs.jmedchem.0c00382⟩
This document is the Accepted Manuscript version of a Published Work that appeared in final form in the Journal of Medicinal Chemistry, copyright © 2021 American Chemical Society, after peer review and technical editing by the publisher. To access t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8215a973d5782c2b47dd3c1eb5542d4f
https://curis.ku.dk/ws/files/313014309/syntenin_manuscript_JMC_revised_120820_VS_1_1_.pdf
https://curis.ku.dk/ws/files/313014309/syntenin_manuscript_JMC_revised_120820_VS_1_1_.pdf
Autor:
Kristian Strømgaard, Christian R. O. Bartling, Thomas M. T. Jensen, Louise Albertsen, Linda M. Haugaard-Kedström
Publikováno v:
ChemBioChem. 19:1119-1122
The intracellular adaptor protein Mint2 binds amyloid precursor protein (APP) and presenilin-1, which are both central constituents of the amyloidogenic pathway associated with Alzheimer's disease (AD). Additional interaction partners have also been
Autor:
Vita Sereikaitė, Thomas M. T. Jensen, Stephan A. Pless, Christian R. O. Bartling, Kristian Strømgaard, Per Jemth
Publikováno v:
Chembiochem : a European journal of chemical biology. 19(20)
All proteins contain characteristic backbones formed of consecutive amide bonds, which can engage in hydrogen bonds. However, the importance of these is not easily addressed by conventional technologies that only allow for side-chain substitutions. B