Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Thomas M. Reeves"'
Autor:
Jason Newton, Terry L. Smith, Lesley D. O'Brien, Linda L. Phillips, Sarah Spiegel, Aron H. Lichtman, Giulia Donvito, Benjamin F. Cravatt, Thomas M. Reeves
Publikováno v:
Cannabis Cannabinoid Res
Background: The endogenous cannabinoid system modulates inflammatory signaling in a variety of pathological states, including traumatic brain injury (TBI). The selective expression of diacylglycerol lipase-β (DAGL-β), the 2-arachidonylglycerol bios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3dbb82efdb929aa29abad94c640644
https://doi.org/10.1089/can.2020.0175
https://doi.org/10.1089/can.2020.0175
Autor:
Alpa Trivedi, Jonathan M. Levine, Alison D. Santucci, Linda J. Noble-Haeusslein, Linda L. Phillips, Thomas M. Reeves
Publikováno v:
Cellular and Molecular Life Sciences. 76:3141-3156
Neurotrauma, a term referencing both traumatic brain and spinal cord injuries, is unique to neurodegeneration in that onset is clearly defined. From the perspective of matrix metalloproteinases (MMPs), there is opportunity to define their temporal pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df42665fb151ffb4a3f937bec4a6eb30
https://doi.org/10.1007/s00018-019-03176-4
https://doi.org/10.1007/s00018-019-03176-4
Publikováno v:
Neuroscience. 371:106-118
Despite the regenerative capacity of the olfactory bulb (OB), head trauma causes olfactory disturbances in up to 30% of patients. While models of olfactory nerve transection, olfactory receptor neuron (ORN) ablation, or direct OB impact have been use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612dfe98153bbf214e25134cebaa349f
https://doi.org/10.1016/j.neuroscience.2017.11.045
https://doi.org/10.1016/j.neuroscience.2017.11.045
Publikováno v:
Exp Neurol
The hippocampus is vulnerable to traumatic brain injury (TBI), and hippocampal damage is associated with cognitive deficits that are often the hallmark of TBI. Recent studies have found that TBI induces enhanced neurogenesis in the dentate gyrus (DG)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f9a8d3cd5be863248bbc7d9b0263e6
https://doi.org/10.1016/j.expneurol.2020.113527
https://doi.org/10.1016/j.expneurol.2020.113527
Publikováno v:
J Neurotrauma
Olfactory receptor axons reinnervate the olfactory bulb (OB) after chemical or transection lesion. Diffuse brain injury damages the same axons, but the time course and regulators of OB reinnervation are unknown. Gelatinases (matrix metalloproteinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b6ad2a40045a77324af4e7ac819e4f
https://pubmed.ncbi.nlm.nih.gov/30444175
https://pubmed.ncbi.nlm.nih.gov/30444175
Autor:
Nicholas H. Russell, Linda L. Phillips, Nancy N. Lee, Adele E. Doperalski, Thomas M. Reeves, Raiford T. Black
Publikováno v:
Brain Research. 1725:146466
Traumatic brain injury (TBI) often presents with focal contusion and parenchymal bleeds, activating heme oxygenase (HO) to degrade released hemoglobin. Here we show that diffuse, midline fluid percussion injury causes time-dependent induction of HO-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7138569dd15a44556a43cd2f0a1cbe
https://doi.org/10.1016/j.brainres.2019.146466
https://doi.org/10.1016/j.brainres.2019.146466
Autor:
Aron H. Lichtman, Thomas M. Reeves, Lesley D. Schurman, Linda L. Phillips, Anthony J. Morales, Nancy N. Lee, Terry L. Smith
Publikováno v:
Neuroscience letters. 653
Although rodent models of traumatic brain injury (TBI) reliably produce cognitive and motor disturbances, behavioral characterization resulting from left and right hemisphere injuries remains unexplored. Here we examined the functional consequences o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0219d83a498ad8964cd437751aea40
https://pubmed.ncbi.nlm.nih.gov/28527714
https://pubmed.ncbi.nlm.nih.gov/28527714
Publikováno v:
Experimental neurology. 283
Axonal injury is present in essentially all clinically significant cases of traumatic brain injury (TBI). While no effective treatment has been identified to date, experimental TBI models have shown promising axonal protection using immunosuppressant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5479ce8b3c071ad08dd30154fb656095
https://pubmed.ncbi.nlm.nih.gov/27302680
https://pubmed.ncbi.nlm.nih.gov/27302680
Publikováno v:
Hippocampus. 21:81-92
This study documents the spatial and temporal expression of three structurally related chondroitin sulfated proteoglycans (CSPGs) during synaptic regeneration induced by brain injury. Using the unilateral entorhinal cortex (EC) lesion model of adapti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a5e7d6b0d86a93a58fdd20a327185c
https://doi.org/10.1002/hipo.20725
https://doi.org/10.1002/hipo.20725
Publikováno v:
Brain Pathology. 20:1055-1068
A high membrane-to-cytoplasm ratio makes axons particularly vulnerable to traumatic injury. Posttraumatic shifts in ionic homeostasis promote spectrin cleavage, disrupt ankyrin linkages and destabilize axolemmal proteins. This study contrasted ankyri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a501ffe97209b1cb49c731319b7f285
https://doi.org/10.1111/j.1750-3639.2010.00412.x
https://doi.org/10.1111/j.1750-3639.2010.00412.x