Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Thomas M. Proctor"'
Autor:
Halina Offner, Sandhya Subramanian, Gregory G. Burrows, Arthur A. Vandenbark, Owen J. T. McCarty, Sushmita Sinha, Jianya Huan, Lisa Miller, Thomas M. Proctor, Roberto Meza-Romero
Publikováno v:
Journal of Neuroimmunology. 225:52-61
Recombinant T cell ligands (RTLs) ameliorate experimental autoimmune encephalomyelitis (EAE) in an antigen-specific manner. We evaluated effects of RTL401 (I-A(s) alpha1beta1+PLP-139-151) on splenocytes from SJL/J mice with EAE to study RTL-T cell to
Publikováno v:
Journal of Neuroimmunology. 220:136-139
Ovarian hormones, including progesterone, are known to have immunomodulatory and neuroprotective effects which may alter the disease course of experimental autoimmune encephalomyelitis (EAE). In the current study, we examined the treatment potential
Publikováno v:
Journal of Neuroscience Research. 88:7-15
The regulatory role of programmed death 1 (PD-1) was investigated in the development of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis. Typical EAE could be induced by immunization without pertussis toxin (PTX)
Autor:
Sushmita Sinha, Lisa Miller, Gregory G. Burrows, Thomas M. Proctor, Sandhya Subramanian, Arthur A. Vandenbark, Halina Offner, Chris Roberts
Publikováno v:
The Journal of Neuroscience. 29:3816-3823
Recombinant T-cell receptor ligands (RTLs) can reverse clinical and histological signs of experimental autoimmune encephalomyelitis (EAE) in an antigen-specific manner, and are currently in clinical trials for treatment of subjects with multiple scle
Autor:
Marjorie R. Grafe, Gregory G. Burrows, Sandhya Subramanian, Halina Offner, Laurie J. Kaler, Arthur A. Vandenbark, Rony Dahan, Sushmita Sinha, Thomas M. Proctor, Jianya Huan
Publikováno v:
The Journal of Neuroscience. 27:12531-12539
Recombinant T-cell receptor ligands (RTLs) can prevent and reverse clinical and histological signs of experimental autoimmune encephalomyelitis (EAE) in an antigen-specific manner and are currently in clinical trials for treatment of subjects with mu
Publikováno v:
The Journal of Comparative Neurology. 502:175-191
Eph receptor tyrosine kinases and their ephrin ligands participate in the control of neuronal growth and migration in a variety of contexts, but the mechanisms by which they guide neuronal motility are still incompletely understood. By using the ente
Autor:
Bruce L. Patton, Bruce G. Gold, Thomas M. Proctor, Dongren Yang, Yukie S. Tarumi, Yong Ping Zhong, Larry S. Sherman, Jeffrey H. Miner, Shin'ichi Takeda, Yuko Miyagoe-Suzuki, Jesse Bierman, Reshma Rangwala
Publikováno v:
The Journal of Cell Biology
Schwann cells form basal laminae (BLs) containing laminin-2 (Ln-2; heterotrimer alpha2beta1gamma1) and Ln-8 (alpha4beta1gamma1). Loss of Ln-2 in humans and mice carrying alpha2-chain mutations prevents developing Schwann cells from fully defasciculat
Autor:
Steven E. Fick, Thomas M. Proctor
Publikováno v:
Journal of Research of the National Institute of Standards and Technology
The National Institute of Standards and Technology (NIST) Conical Reference Transducer (CRT) is designed for purposes requiring frequency response characteristics much more uniform than those attainable with ultrasonic transducers conventionally used
Autor:
Thomas M. Proctor, Chunhe Wang, Yuexin Li, Halina Offner, Babak Dehghani, Arthur A. Vandenbark, Laurie J. Kaler
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(5)
Although estrogens exert a pronounced protective effect on multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE), their therapeutic application has been limited by undesirable side effects thought to be mediated pri
Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function
Autor:
Doris Kretzschmar, Roland Strauss, Burkhard Poeck, Katia Carmine-Simmen, Tilman Triphan, Thomas M. Proctor, Jakob Andreas Tschäpe
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 2, Pp 274-281 (2009)
The accumulation of amyloid-beta (Abeta) into plaques is a hallmark feature of Alzheimer's disease (AD). While amyloid precursor protein (APP)-related proteins are found in most organisms, only Abeta fragments from human APP have been shown to induce