Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas M. Luby"'
Autor:
Radha Ramesh, Barbara S. Slusher, Gregory D. Wands, Min Yang, Thomas M. Luby, Mary Lynne Hedley, Christine M. Barbon
Publikováno v:
Cellular Immunology. 262:150-161
Cyclophosphamide in combination with immunotherapeutic approaches preferentially impinges on Treg activity and allows for robust generation of T cell effectors. Reduced dosages of cyclophosphamide are necessary to restrict its cytotoxic effects to th
Autor:
Joycelyn Vardo, Thomas M. Luby, Erik Selsing, Nicole D’Avirro, Carol E. Schrader, Irene M. Min, Janet Stavnezer
Publikováno v:
Immunity. 19:515-524
Deficiencies of the Msh2 protein or the Smu tandem repeat (SmuTR) sequences each reduce isotype switching in mice by about 2- to 3-fold. We find that switching in mice deficient for both Msh2 and SmuTR is nearly ablated. We propose that the SmuTR pro
Publikováno v:
European Journal of Immunology. 31:2866-2875
Analyses of H-chain transgenes have indicated that sequences situated between the μ intronic enhancer and the Cμ exons are important for μ gene expression. We have analyzed several variant μ transgenes and find that a sequence element located wit
Publikováno v:
The Journal of Experimental Medicine
Class switch DNA recombinations change the constant (C) region of the antibody heavy (H) chain expressed by a B cell and thereby change the antibody effector function. Unusual tandemly repeated sequence elements located upstream of H chain gene exons
Autor:
Mark Matijevic, Roman M. Chicz, Robert G. Urban, Thomas M. Luby, Mary Lynne Hedley, Christa Lajoie
Publikováno v:
Cellular Immunology
Highlights ► Immunization with amolimogene induces T cells specific to HPV in HSIL subjects. ► Amolimogene expresses T cell epitopes from E6/E7 proteins of HPV types 16 and 18. ► 7 of 11 subjects with amolimogene induced HPV 16/18 T cells, resp
Autor:
Mary Lynne Hedley, Urban Ramstedt, Thomas M. Luby, Lisa Baker, Christa Lajoie, Christine M. Barbon
Publikováno v:
Vaccine. 28(50)
Immunization with plasmid DNA that has been encapsulated in poly lactide-co-glycolide (PLG) microparticles targets the plasmid DNA to antigen presenting cells and elicits immune responses to the encoded antigen(s). Application of a series of electric
Autor:
Thomas M Luby
Publikováno v:
Expert review of vaccines. 7(7)
The role that the immune system plays in limiting tumor formation and growth is becoming increasingly clear and passive immunotherapeutic approaches, such as the use of monoclonal antibodies, are now being successfully applied in clinical practice. A
Autor:
Mary Lynne Hedley, J.Steven Kornher, Lisa Baker, Thomas M. Luby, Urban Ramstedt, Geoffrey Cole
Publikováno v:
Clinical immunology (Orlando, Fla.). 112(1)
Injection of microparticle-encapsulated DNA elicits immune responses to plasmid-encoded antigens in mice and humans. Cytochrome P450 CYP1B1 (CYP1B1) is a member of the CYP1 P450 enzyme family that is overexpressed in a variety of solid tumors. The wo
Publikováno v:
Blood. 112:5391-5391
AKR-501 (1-(3-Chloro-5-{[4-(4-chloro-2-thienyl)-5-(4-cyclohexylpiperazin-1-yl) thiazol-2-yl]carbamoyl}-2-pyridyl)piperidine-4-carboxylic acid, formerly known as YM-477) is an orally-active full agonist of the thrombopoietin (TPO) receptor, c-Mpl. Hum