Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Thomas M. H. Lee"'
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1823 (2021)
Mortality and morbidity associated with COVID-19 continue to be significantly high worldwide, owing to the absence of effective treatment strategies. The emergence of different variants of SARS-CoV-2 is also a considerable source of concern and has l
Externí odkaz:
https://doaj.org/article/9191803a1c9d4026b8bafe33b42ab739
Autor:
Fei Meng, Gilman Kit-Hang Siu, Bobo Wing-Yee Mok, Jiahong Sun, Kitty S. C. Fung, Jimmy Yiu-Wing Lam, Nonthaphat Kent Wong, Lealem Gedefaw, Shumeng Luo, Thomas M. H. Lee, Shea Ping Yip, Chien-Ling Huang
Publikováno v:
Cells, Vol 10, Iss 7, p 1762 (2021)
MicroRNAs (miRNAs) are critical regulators of gene expression that may be used to identify the pathological pathways influenced by disease and cellular interactions. Viral miRNAs (v-miRNAs) encoded by both DNA and RNA viruses induce immune dysregulat
Externí odkaz:
https://doaj.org/article/95459f3ed9884974b5bed184684af724
Autor:
Shiyao Wang, Ailin Qin, Li Yin Chau, Eunice W. T. Fok, Mei Yue Choy, Christopher J. Brackman, Gilman K. H. Siu, Chien-Ling Huang, Shea Ping Yip, Thomas M. H. Lee
Publikováno v:
ACS Applied Materials & Interfaces. 14:35299-35308
Loop-mediated isothermal amplification (LAMP) has received considerable attention for decentralized (point-of-care and on-site) nucleic acid testing in view of its simple temperature control (60-65 °C) and short assay time (15-60 min). There remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253241b679bc58bdf3df28021aacb572
https://doi.org/10.1021/acsami.2c02508
https://doi.org/10.1021/acsami.2c02508
Autor:
Kitty S. C. Fung, Thomas M. H. Lee, Gilman Kit Hang Siu, Lealem Gedefaw, Jiahong Sun, Shumeng Luo, Fei Meng, Bobo Wing-Yee Mok, Chien-Ling Huang, Shea Ping Yip, Nonthaphat Kent Wong, Jimmy Yiu-Wing Lam
Publikováno v:
Cells
Cells, Vol 10, Iss 1762, p 1762 (2021)
Cells, Vol 10, Iss 1762, p 1762 (2021)
MicroRNAs (miRNAs) are critical regulators of gene expression that may be used to identify the pathological pathways influenced by disease and cellular interactions. Viral miRNAs (v-miRNAs) encoded by both DNA and RNA viruses induce immune dysregulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e173428971241334f510618cf60421b
http://europepmc.org/articles/PMC8307234
http://europepmc.org/articles/PMC8307234
Autor:
Shiyao Wang, Thomas M. H. Lee
Publikováno v:
Detection Methods in Precision Medicine ISBN: 9781788017619
Nucleic acid detection in point-of-care settings would bring tremendous benefits to early diagnosis. Colorimetric nanoprobes have proved to be promising for point-of-care testing (POCT) thanks to their simple result readout (qualitative visual and/or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44122bb162db545697a4337c58814ab1
https://doi.org/10.1039/9781788019958-00279
https://doi.org/10.1039/9781788019958-00279
Publikováno v:
Journal of materials chemistry. B. 4(23)
In this work, we developed a simple and sensitive colorimetric detection platform for specific DNA sequences by using peroxidase mimetics of platinum nanoparticles supported on reduced graphene oxide. This nanocomposite possessed the combined advanta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdeda23a287bb64101841e730bd42ec4
https://pubmed.ncbi.nlm.nih.gov/32264609
https://pubmed.ncbi.nlm.nih.gov/32264609
Publikováno v:
Small. 10:1495-1499
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b7b73c039171550390423325eaaa54
https://doi.org/10.1002/smll.201302348
https://doi.org/10.1002/smll.201302348
Simple and Sensitive Electrochemical DNA Detection of Primer Generation-Rolling Circle Amplification
Publikováno v:
Electroanalysis. 25:1310-1315
A new electrochemical sequence-specific DNA detection platform based on primer generation-rolling circle amplification (PG-RCA), methylene blue (MB) redox indicator, and indium tin oxide (ITO) electrode is reported. In the presence of a specific targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ba796c98fb11a7c0f5aabbd6634b4bd
https://doi.org/10.1002/elan.201300029
https://doi.org/10.1002/elan.201300029
Publikováno v:
Nano Research. 5:585-594
We report a simple method of enhancing the chemical stability of monothiol-modified oligonucleotide-gold and -silver nanoparticle conjugates by a thin silica reinforcement coating. Conventional conjugates prepared by chemisorption of monothiol-modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72eafbb8df270a3cb6ce5d9bf1c93be1
https://doi.org/10.1007/s12274-012-0244-z
https://doi.org/10.1007/s12274-012-0244-z
Publikováno v:
Small. 8:214-219
A facile silica coating significantly enhances the thermal stability and polymerase chain reaction (PCR) compatibility of oligonucleotide-gold nanoparticle conjugates, thus enabling colorimetric detection of PCR results in a closed-tube format. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de23f60d16d3c7b93298016d7e3522b
https://doi.org/10.1002/smll.201101925
https://doi.org/10.1002/smll.201101925