Zobrazeno 1 - 10
of 473
pro vyhledávání: '"Thomas M. Gress"'
Autor:
Silke D. Werle, Nensi Ikonomi, Ludwig Lausser, Annika M. T. U. Kestler, Felix M. Weidner, Julian D. Schwab, Julia Maier, Malte Buchholz, Thomas M. Gress, Angelika M. R. Kestler, Hans A. Kestler
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-17 (2023)
Abstract Pancreatic neuroendocrine tumors (PanNETs) are a rare tumor entity with largely unpredictable progression and increasing incidence in developed countries. Molecular pathways involved in PanNETs development are still not elucidated, and speci
Externí odkaz:
https://doaj.org/article/4ccc6dba9fcc4072b055b2958bdc1426
Autor:
Maren Stark, Marina Nicolai, Marina Tatura, Corinna U. Keber, Andreas Kaufmann, Ho‐Ryun Chung, Emily P. Slater, Christopher Heeschen, Rita T. Lawlor, Aldo Scarpa, Detlef K. Bartsch, Thomas M. Gress, Stefan Bauer, Malte Buchholz
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8542-8556 (2023)
Abstract Background Toll‐like receptors (TLRs) are gaining attention for their potential to influence tumor biology both on the level of the tumor cells as well as on the level of the surrounding inflammatory stroma. Previous studies resulted in pa
Externí odkaz:
https://doaj.org/article/d14b8a3d788f4c6caf9c5dd955d6c74f
Autor:
Sebastian Krug, Thomas Kegel, Thomas M. Gress, Anja Rinke, Leonidas Apostolidis, Henning Jann, Alexander König, Dieter Hörsch, Jörg Schrader, Thomas J. Ettrich, Michael Richter, Jörg Steighardt, Patrick Michl
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Cytotoxic chemotherapy combinations and targeted agents represent established treatment concepts in advanced pancreatic neuroendocrine tumors (PNETs). However, response rates, side effects and outcome data strongly vary among thes
Externí odkaz:
https://doaj.org/article/19ea4eac44d448f1a68eca27024409f7
Autor:
Maik Luu, Zeno Riester, Adrian Baldrich, Nicole Reichardt, Samantha Yuille, Alessandro Busetti, Matthias Klein, Anne Wempe, Hanna Leister, Hartmann Raifer, Felix Picard, Khalid Muhammad, Kim Ohl, Rossana Romero, Florence Fischer, Christian A. Bauer, Magdalena Huber, Thomas M. Gress, Matthias Lauth, Sophia Danhof, Tobias Bopp, Thomas Nerreter, Imke E. Mulder, Ulrich Steinhoff, Michael Hudecek, Alexander Visekruna
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The activity of immune cells can be regulated by the microbiome. Here, the authors show that the fatty acids pentanoate and butyrate—normally released by the microbiome—increase the anti-tumour activity of cytotoxic T lymphocytes and chimeric ant
Externí odkaz:
https://doaj.org/article/b049d4b46e18405fa995dd666bce268c
Autor:
Petros Stathopoulos, Malte Zumblick, Sabine Wächter, Leif Schiffmann, Thomas M. Gress, Detlef Bartsch, Guido Seitz, Ulrike W. Denzer
Publikováno v:
Endoscopy International Open, Vol 10, Iss 05, Pp E686-E693 (2022)
Background and study aims Acute esophageal perforation is a potentially life-threating condition that demands a multidisciplinary approach. Based on recently published data indicating that EVT may be effective in managing esophageal perforation, we r
Externí odkaz:
https://doaj.org/article/218e18fbec384bf3b7ff36bbe6a5af42
Autor:
Elena Nasiri, Malte Student, Katrin Roth, Nadya Siti Utami, Magdalena Huber, Malte Buchholz, Thomas M. Gress, Christian Bauer
Publikováno v:
Cells, Vol 12, Iss 3, p 456 (2023)
In pancreatic ductal adenocarcinoma (PDAC), the infiltration of CD8+ cytotoxic T cells (CTLs) is an important factor in determining prognosis. The migration pattern and interaction behavior of intratumoral CTLs are pivotal to tumor rejection. NLRP3-d
Externí odkaz:
https://doaj.org/article/39f184cb59d640c1976c25d95e4731e2
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Brain metastases (BM) are rarely reported in patients with neuroendocrine carcinoma (NEC) of non-lung origin and neuroendocrine tumors (NET) of the gastroenteropancreatic (GEP) or bronchopulmonary system. However, symptomatic brai
Externí odkaz:
https://doaj.org/article/2fb3551e5d6c4020ac02fc763cd914dd
Autor:
Albert Job, Lisa-Maria Schmitt, Lisa von Wenserski, Brigitte Lankat-Buttgereit, Thomas M. Gress, Malte Buchholz, Eike Gallmeier
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 11, Pp 1135-1143 (2018)
The phosphoinositide 3-kinase–related kinase ATR is a central regulator of the DNA damage response. Its chemical inhibition eliminates subsets of cancer cells in various tumor types. This effect is caused at least partly by the synthetically lethal
Externí odkaz:
https://doaj.org/article/2b6c7f300e104b399bc8c52c314357dd
Autor:
Sebastian Krug, Maryam Khosravian, Julia Weissbach, Katharina George, Marko Damm, Jakob Garbe, Jens Walldorf, Philipp A. Reuken, Tania Amin, Alexander Siebenhüner, Jonas Rosendahl, Thomas M. Gress, Patrick Michl, Jörg Schrader, Anja Rinke
Publikováno v:
Cancers, Vol 14, Iss 3, p 613 (2022)
The assessment of cancer patient care during the COVID-19 pandemic has been mainly reported from a physician’s perspective. Patients with rare tumor entities such as neuroendocrine tumors (NET), which require a complex and specialized care infrastr
Externí odkaz:
https://doaj.org/article/95cd675a63be415c8d13a57c658ff823
Autor:
Silvia Ottaviani, Justin Stebbing, Adam E. Frampton, Sladjana Zagorac, Jonathan Krell, Alexander de Giorgio, Sara M. Trabulo, Van T. M. Nguyen, Luca Magnani, Hugang Feng, Elisa Giovannetti, Niccola Funel, Thomas M. Gress, Long R. Jiao, Ylenia Lombardo, Nicholas R. Lemoine, Christopher Heeschen, Leandro Castellano
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
In pancreatic ductal adenocarcinoma, TGF-β/Activin induce epithelial-to-mesenchymal transition (EMT) and stemness. Here, the authors show that TGF-β induces pro-tumourigenic miR-100 and miR-125b, but blocks anti-tumourigenic let-7a maturation via L
Externí odkaz:
https://doaj.org/article/6b26f0de8fb24a82b752ef7f07fc000b