Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Thomas M. Glenn"'
Publikováno v:
Drug Development Research. 5:327-336
The effect of 6(2-isopropylaminopropyl)-3-pyridinol fumarate (CGS 5649B) on mechanical function and tissue energy levels of the isolated rat heart subjected to 35 min of global ischemia and 25 min of reperfusion was examined. Hearts perfused with buf
Publikováno v:
Journal of Pharmaceutical Sciences. 73:1748-1751
In this report a sensitive gas chromatographic assay for cetiedil, a candidate antisickling agent, in human plasma is described. After a triple extraction procedure, cetiedil was analyzed without derivatization with a nitrogen-phosphorus detector (wi
Autor:
Thomas M. Glenn, Howard H.H Oei, Stephen W. Schaffer, William E Hughes, Gesina L. Longenecker
Publikováno v:
American Heart Journal. 106:1077-1081
Platelets are belleved to play a role in the pathologic sequelae of acute myocardial ischemia. Several of the compounds generated and released by activated platelets during cardiac ischemia may contribute to the production of cellular necrosis (free
Autor:
Thomas M. Glenn, Allan M. Lefer
Publikováno v:
Circulation Research. 27:783-797
Splanchnic arterial occlusion (SAO) for 2 hours followed by release of the occlusion in cats produced a lethal shock state characterized by cardiovascular collapse. Release of the occlusion resulted in a 45% fall in mean arterial blood pressure withi
Autor:
Allon M. Lefer, Thomas M. Glenn
Publikováno v:
Circulation Research. 29:338-349
The pathogenesis of circulatory shock has been previously associated with the plasma accumulation of a myocardial depressant factor (MDF). The plasma accumulation of MDF in cats subjected to hemorrhagic shock was associated with marked increases (P
Autor:
Alfredo M. Lopez-Rasi, Tersito S. Serate, Stephen L. Wangensteen, Anthony C. Beardsley, Allan M. Lefer, Wayne W. Ferguson, John R. Morris, Thomas M. Glenn
Publikováno v:
Annals of Surgery. 176:120-127
Autor:
Thomas M. Glenn, Gerald J. Kelliher
Publikováno v:
European Journal of Pharmacology. 24:410-414
Prostaglandin E 1 (PGE 1 ) was infused i.v. to a total dose of 50 μg/kg to cats anesthetized with pentobarbital. PGE 1 increased significantly the dose of ouabain necessary to produce premature ventricular complexes, ventricular tachycardia and deat
Publikováno v:
Journal of Surgical Research. 11:364-374
The isolated cat pancreas perfused with a physiological salt solution plus low molecular-weight dextran functions satisfactorally for at least 2 1 2 hours. Evidence for stability and functional integrity of the preparation included measurements of va
Autor:
Thomas M. Glenn, Roy D. Goldfarb
Publikováno v:
European journal of pharmacology. 37(1)
The effects of dexamethasone sodium phosphate (DSP), 5 mg/kg, administration on the biochemical alterations in hepatic tissue subsequent to the production of splanchnic artery occlusion (SAO) shock was investigated. Following the induction of SAO sho