Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Thomas M. Bauer"'
Autor:
Jean-Luc Diehl, Claude Capron, Thomas M. Bauer, Etienne Puymirat, Yasmine Ouzegdouh, Elisabeth Cramer-Bordé, John Martin
Publikováno v:
Experimental Hematology. 63:22-27.e3
Animal evidence that platelet production occurs in the lungs is growing. We have investigated whether there is evidence to support pulmonary platelet production from studies using human conditions. We documented the presence of megakaryocytes (MKs) i
Publikováno v:
Blood. 105:2480-2486
Although dendritic cells (DCs) strongly stimulate the immune response, they can also induce unresponsiveness. Recently, a human monocyte-derived DC subpopulation was described that constitutively expresses indoleamine 2,3-dioxygenase (IDO). These DCs
Publikováno v:
Transplantation. 77:1761-1764
Background Deliberately generated tolerogenic dendritic cells (DC) might be a useful tool for induction of donor-specific tolerance in transplantation. In this article, the authors study the effect of mitomycin C (MMC)-treated DC on rat T cells and d
Publikováno v:
Clinica Chimica Acta. 340:27-40
The ubiquitin-proteasome pathway constitutes the major system for nuclear and extralysosomal cytosolic protein degradation in eukaryotic cells. A plethora of cell proteins implicated in the maintenance and regulation of essential cellular processes u
Publikováno v:
Biochemical and Biophysical Research Communications. 310:347-354
The immunosuppressive agent cyclosporin A (CsA), which interferes with signal transduction pathways leading to cytokine gene transcription in activated T cells, was investigated regarding its ability to induce apoptosis in T cells undergoing cell cyc
Autor:
Lars Röse, Helmut Simon, C Dufter, Thomas M. Bauer, Peter Terness, Andrea Watzlik, Gerhard Opelz
Publikováno v:
Journal of Experimental Medicine. 196:447-457
Indoleamine 2,3-dioxygenase (IDO), an enzyme involved in the catabolism of tryptophan, is expressed in certain cells and tissues, particularly in antigen-presenting cells of lymphoid organs and in the placenta. It was shown that IDO prevents rejectio
Autor:
Claude Capron, Claire Dunois-Lardé, Dominique Baruch, Elisabeth Cramer-Bordé, Serge Fichelson, Thomas M. Bauer
Publikováno v:
Blood. 114(9)
Platelets originate from megakaryocytes (MKs) by cytoplasmic elongation into proplatelets. Direct platelet release is not seen in bone marrow hematopoietic islands. It was suggested that proplatelet fragmentation into platelets can occur intravascula
Autor:
Guenter Germann, Steffen Baumeister, Peter Terness, Christian Andreas Radu, Christian Kleist, Lucian P. Jiga, Gerhard Opelz, Thomas M. Bauer, Martha Maria Gebhard, Nikolaus Bosch
Publikováno v:
Plastic and reconstructive surgery. 119(7)
Hand transplantations have intensified immunological research into composite tissue allotransplantation to induce tolerance. Pregnancy is a successful, natural model of immunological tolerance. The enzyme indoleamine 2,3-deoxygenase plays an importan
Autor:
Lucian P. Jiga, Thomas M. Bauer, Jing-Jing Chuang, Peter Terness, Gerhard Opelz, Marco Randazzo
Publikováno v:
Transplant international : official journal of the European Society for Organ Transplantation. 18(1)
Pregnancy is a natural model of successful tolerance induction against allogeneic tissues. Recent studies pointed to a role of indoleamine 2,3-dioxygenase (IDO), a tryptophan-degrading enzyme expressed in the placenta, in mediation of T-cell suppress
Autor:
Peter, Terness, Thomas M, Bauer, Lars, Röse, Christoph, Dufter, Andrea, Watzlik, Helmut, Simon, Gerhard, Opelz
Publikováno v:
The Journal of Experimental Medicine
Indoleamine 2,3-dioxygenase (IDO), an enzyme involved in the catabolism of tryptophan, is expressed in certain cells and tissues, particularly in antigen-presenting cells of lymphoid organs and in the placenta. It was shown that IDO prevents rejectio