Výsledky vyhledávání - "Thomas M Stulnig"

Akademický článek

Antibody-mediated targeting of cleavage-specific OPN-T cell interactions.

Autor: Bettina Wanko, Matteo Tardelli, Alexander Jürets, Angelika Neuhofer, Gerhard Prager, John Morser, Lawrence L Leung, Günther Staffler, Maximilian Zeyda, Thomas M Stulnig

Publikováno v: PLoS ONE, Vol 14, Iss 4, p e0214938 (2019)

T cells are crucial players in obesity-mediated adipose tissue inflammation. We hypothesized that osteopontin (OPN), an inflammatory protein with enhanced activity when proteolytically cleaved, affects the number of viable T cells in adipose tissue a

Externí odkaz: https://doaj.org/article/ab0a37a4536d4796b1998b8bb7a7db63

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Identification of Matrix Metalloproteinase-12 as a Candidate Molecule for Prevention and Treatment of Cardiometabolic Disease

Autor: Melina Amor, Veronica Moreno-Viedma, Alisina Sarabi, Nicole G Grün, Bianca Itariu, Lukas Leitner, Irene Steiner, Martin Bilban, Keiichi Kodama, Atul J Butte, Guenther Staffler, Maximilian Zeyda, Thomas M Stulnig

Publikováno v: Molecular Medicine, Vol 22, Iss 1, Pp 487-496 (2016)

Abstract Obesity is strongly associated with metabolic syndrome, a combination of risk factors that predisposes to development of the cardiometabolic diseases: atherosclerotic cardiovascular disease and type 2 diabetes mellitus. Prevention of metabol

Externí odkaz: https://doaj.org/article/4e75b4e41d90433d863c9e7094b4a6ab

Zobrazit plný text záznamu

Akademický článek

Inhibition of Cellular Adhesion by Immunological Targeting of Osteopontin Neoepitopes Generated through Matrix Metalloproteinase and Thrombin Cleavage.

Autor: Alexander Jürets, Marie Le Bras, Günther Staffler, Gesine Stein, Lukas Leitner, Angelika Neuhofer, Matteo Tardelli, Edvin Turkof, Maximilian Zeyda, Thomas M Stulnig

Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0148333 (2016)

Osteopontin (OPN), a secreted protein involved in inflammatory processes and cancer, induces cell adhesion, migration, and activation of inflammatory pathways in various cell types. Cells bind OPN via integrins at a canonical RGD region in the full l

Externí odkaz: https://doaj.org/article/df861ee86c3841409a854f48e64c1ab4

Zobrazit plný text záznamu

Akademický článek

Insulin-like growth factor 1 predicts post-load hypoglycemia following bariatric surgery: a prospective cohort study.

Autor: Bianca K Itariu, Maximilian Zeyda, Gerhard Prager, Thomas M Stulnig

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e94613 (2014)

Postprandial hypoglycemia is a complication following gastric bypass surgery, which frequently remains undetected. Severe hypoglycemic episodes, however, put patients at risk, e.g., for syncope. A major cause of hypoglycemia following gastric bypass

Externí odkaz: https://doaj.org/article/24522ad6c74847789a29744fb15f0e83

Zobrazit plný text záznamu

Akademický článek

Treatment with n-3 polyunsaturated fatty acids overcomes the inverse association of vitamin D deficiency with inflammation in severely obese patients: a randomized controlled trial.

Autor: Bianca K Itariu, Maximilian Zeyda, Lukas Leitner, Rodrig Marculescu, Thomas M Stulnig

Publikováno v: PLoS ONE, Vol 8, Iss 1, p e54634 (2013)

Obesity affects the vitamin D status in humans. Vitamin D and long-chain n-3 polyunsaturated fatty acids (PUFA) provide benefit for the prevention of fractures and cardiovascular events, respectively, and both are involved in controlling inflammatory

Externí odkaz: https://doaj.org/article/3faa81c0d815404087ed4fc73ce6af56

Zobrazit plný text záznamu

Akademický článek

CTX (crosslaps) rather than osteopontin is associated with disturbed glucose metabolism in gestational diabetes.

Autor: Yvonne Winhofer, Florian W Kiefer, Ammon Handisurya, Andrea Tura, Katharina Klein, Barbara Schneider, Rodrig Marculescu, Oswald F Wagner, Giovanni Pacini, Anton Luger, Thomas M Stulnig, Alexandra Kautzky-Willer

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e40947 (2012)

OBJECTIVE: Reciprocal interaction between bone and glucose metabolism might play a pivotal role in the development of type 2 diabetes. We recently demonstrated that osteocalcin is increased in women with gestational diabetes (GDM) compared to healthy

Externí odkaz: https://doaj.org/article/a132c264896749b0b4b1cc4b9f1bfe2a

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání