Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Thomas M Magin"'
Autor:
Miriam S Weber, Matthias Eibauer, Suganya Sivagurunathan, Thomas M Magin, Robert D Goldman, Ohad Medalia
Publikováno v:
eLife, Vol 10 (2021)
Keratin intermediate filaments are an essential and major component of the cytoskeleton in epithelial cells. They form a stable yet dynamic filamentous network extending from the nucleus to the cell periphery, which provides resistance to mechanical
Externí odkaz:
https://doaj.org/article/f4deaa2647f04374a74ffe95884de6d6
Autor:
Mahmod Muhsen, Martina Protschka, Laura E Schneider, Uwe Müller, Gabriele Köhler, Thomas M Magin, Mathias Büttner, Gottfried Alber, Sabine Siegemund
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210504 (2019)
ORF virus (ORFV) is the causative agent of contagious ecthyma, a pustular dermatitis of small ruminants and humans. Even though the development of lesions caused by ORFV was extensively studied in animals, only limited knowledge exists about the lesi
Externí odkaz:
https://doaj.org/article/d6ba7ac0c1a64d9290339ccb33bfbe3f
Publikováno v:
eLife, Vol 5 (2016)
Intermediate filament (IF) proteins, including nuclear lamins and cytoplasmic IF proteins, are essential cytoskeletal components of bilaterian cells. Despite their important role in protecting tissues against mechanical force, no cytoplasmic IF prote
Externí odkaz:
https://doaj.org/article/4c2665e578384513a29e649e904911f0
Autor:
Katharina König, Lydia Meder, Cornelia Kröger, Linda Diehl, Alexandra Florin, Ursula Rommerscheidt-Fuss, Philip Kahl, Eva Wardelmann, Thomas M Magin, Reinhard Buettner, Lukas C Heukamp
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57996 (2013)
Epithelial-to-mesenchymal transition (EMT), the phenotypical change of cells from an epithelial to a mesenchymal type, is thought to be a key event in invasion and metastasis of adenocarcinomas. These changes involve loss of keratin expression as wel
Externí odkaz:
https://doaj.org/article/80708e14f49540c2bf49cca0a3aa43ab
Autor:
Jingyuan Sun, Pei Li, Honglian Gui, Laure Rittié, David B. Lombard, Katrin Rietscher, Thomas M. Magin, Qing Xie, Li Liu, M. Bishr Omary
Publikováno v:
JCI Insight, Vol 8, Iss 14 (2023)
Keratin (K) and other intermediate filament (IF) protein mutations at conserved arginines disrupt keratin filaments into aggregates and cause human epidermolysis bullosa simplex (EBS; K14-R125C) or predispose to mouse liver injury (K18-R90C). The cha
Externí odkaz:
https://doaj.org/article/6e147275c606494284720d71e3764a41
Autor:
Romy Winkler, Marianne Quaas, Stefan Glasmacher, Uwe Wolfrum, Torsten Thalheim, Jörg Galle, Knut Krohn, Thomas M. Magin, Gabriela Aust
Publikováno v:
Cells, Vol 12, Iss 13, p 1677 (2023)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/312d4866bd2a42a5b6bfcc161180f2f2
Autor:
Nicole Golob-Schwarzl, Kira Bettermann, Anita Kuldeep Mehta, Sonja M. Kessler, Julia Unterluggauer, Stefanie Krassnig, Kensuke Kojima, Xintong Chen, Yujin Hoshida, Nabeel M. Bardeesy, Heimo Müller, Vendula Svendova, Michael G. Schimek, Clemens Diwoky, Alexandra Lipfert, Vineet Mahajan, Cornelia Stumptner, Andrea Thüringer, Leopold F. Fröhlich, Tatjana Stojakovic, K.P.R. Nilsson, Thomas Kolbe, Thomas Rülicke, Thomas M. Magin, Pavel Strnad, Alexandra K. Kiemer, Richard Moriggl, Johannes Haybaeck
Publikováno v:
Translational Oncology, Vol 12, Iss 2, Pp 256-268 (2019)
BACKGROUND & AIMS: Steatohepatitis (SH) and SH-associated hepatocellular carcinoma (HCC) are of considerable clinical significance. SH is morphologically characterized by steatosis, liver cell ballooning, cytoplasmic aggregates termed Mallory-Denk bo
Externí odkaz:
https://doaj.org/article/82f259d1149e4b69bf2a4846ca5d9eee
Autor:
Franziska Vielmuth, Elias Walter, Michael Fuchs, Mariya Y. Radeva, Fanny Buechau, Thomas M. Magin, Volker Spindler, Jens Waschke
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Keratins are crucial for the anchorage of desmosomes. Severe alterations of keratin organization and detachment of filaments from the desmosomal plaque occur in the autoimmune dermatoses pemphigus vulgaris and pemphigus foliaceus (PF), which are main
Externí odkaz:
https://doaj.org/article/90b30de2c0f44adaa76449f0e519a026
Autor:
Romy Winkler, Marianne Quaas, Stefan Glasmacher, Uwe Wolfrum, Torsten Thalheim, Jörg Galle, Knut Krohn, Thomas M. Magin, Gabriela Aust
Publikováno v:
Cells; Volume 11; Issue 19; Pages: 3151
Among the 33 human adhesion G-protein-coupled receptors (aGPCRs), a unique subfamily of GPCRs, only ADGRF4, encoding GPR115, shows an obvious skin-dominated transcriptomic profile, but its expression and function in skin is largely unknown. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8008396ad64bb2d27916a1334f3cd03
Autor:
Mechthild Hatzfeld, Thomas M. Magin
Publikováno v:
Journal of Investigative Dermatology. 142:272-274
Single gene disorders are ideally suited to establish robust genotype‒phenotype correlations and provide excellent opportunities to understand molecular pathomechanisms with relevance to complex disorders. The observation that patients diagnosed wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::167d358a35859fc9010b508061378c8e
https://doi.org/10.1016/j.jid.2021.08.389
https://doi.org/10.1016/j.jid.2021.08.389