Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Thomas M Green"'
Autor:
James M. McFarland, Zandra V. Ho, Guillaume Kugener, Joshua M. Dempster, Phillip G. Montgomery, Jordan G. Bryan, John M. Krill-Burger, Thomas M. Green, Francisca Vazquez, Jesse S. Boehm, Todd R. Golub, William C. Hahn, David E. Root, Aviad Tsherniak
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Integrated analyses of multiple large-scale screenings can be complicated by batch effects and technical artefacts. McFarland et al. introduce DEMETER2, a hierarchical model coupled with model-based normalization, which allows the assessment of diffe
Externí odkaz:
https://doaj.org/article/d0eb361d0bb14b90ba18bfe3b6bb1fd5
Publikováno v:
Journal of the American Academy of Orthopaedic Surgeons. 30:1036-1038
Poor oral health is common in the United States; however, it is much more common in African Americans, Hispanics, and other racial/ethnic minorities. Almost one in five low-income adults states that their mouth and teeth are in poor condition. Twenty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7486f2d8181608065f0d9041f3acf7
https://doi.org/10.5435/jaaos-d-21-00426
https://doi.org/10.5435/jaaos-d-21-00426
Autor:
Anthony P. Machado, Thomas M. Green, Matthew L. Ferguson, Eddie C. Davis, Gaby G. Dagher, John S.F. Martin Jr.
Publikováno v:
Evolutionary Intelligence. 14:331-343
Nature has been using DNA to store biological data for millions of years, and finally humans are learning to use the same medium for our own data. In this paper, we survey the field of cellular DNA encoding, where encoding schemes are used to insert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e9ddb15bbe8fb830d7ce69a8b77914e
https://doi.org/10.1007/s12065-019-00202-z
https://doi.org/10.1007/s12065-019-00202-z
Autor:
Thomas M. Green, Timothy L. Andersen
Publikováno v:
GECCO Companion
Understanding how the complex interactions of the problem-algorithm combination lead to an algorithm's search performance is arguably one of the most important open questions in metaheuristic algorithm theory. Examination of the fitness landscape doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d27394ad51b04739562c91bef0d435d
https://doi.org/10.1145/3377929.3398140
https://doi.org/10.1145/3377929.3398140
Autor:
Karsten Krug, Vickie M. Wang, Karl R. Clauser, Federica Piccioni, Zhe Ji, Joshua M. Dempster, Briana Fritchman, Ginevra Botta, Adam Brown, Victor Luria, Jacob D. Jaffe, Zohra Kalani, Thomas M Green, Amy Goodale, Nicholas J. Lyons, Jennifer Roth, Xiaoping Yang, Oana M. Enache, Amir Karger, Douglas Alan, Marc W. Kirschner, Todd R. Golub, David E. Root, Li Wang, John R. Prensner, Karolina Stumbraite
Publikováno v:
Nat Biotechnol
A key question in genome research is whether biologically active proteins are restricted to the ∼20,000 canonical, well-annotated genes, or rather extend to the many non-canonical open reading frames (ORFs) predicted by genomic analyses. To address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3223047384d397a51b447eb9ecb5af4
Autor:
Jesse S. Boehm, Hanna Najgebauer, John G. Doench, Francisca Vazquez, Joshua M. Dempster, Todd R. Golub, Victor A. Zhivich, Sasha Pantel, Charlotte M. Beaver, Emanuel Gonçalves, Clare Pacini, Fiona M. Behan, William C. Hahn, John M. Krill-Burger, Aviad Tsherniak, Rebecca Shepherd, David E. Root, Leopold Parts, Thomas M Green, Felicity Allen, Scott T. Younger, Kosuke Yusa, Francesco Iorio, Mathew J. Garnett
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Genome-scale CRISPR-Cas9 viability screens performed in cancer cell lines provide a systematic approach to identify cancer dependencies and new therapeutic targets. As multiple large-scale screens become available, a formal assessment of the reproduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ed15e6e1a59a105b428d608a6cb9c5
https://pubmed.ncbi.nlm.nih.gov/32091251
https://pubmed.ncbi.nlm.nih.gov/32091251
Autor:
Zhe Ji, Ginevra Botta, Todd R. Golub, Victor Luria, Joshua M. Dempster, Nicholas J. Lyons, Briana Fritchman, Federica Piccioni, Karolina Stumbraite, Karl R. Clauser, Jacob D. Jaffe, Zohra Kalani, David E. Root, Vickie M. Wang, Li Wang, Douglas Alan, Oana M. Enache, Adam Brown, Marc W. Kirschner, Jennifer Roth, Thomas M Green, Karsten Krug, John R. Prensner, Amy Goodale, Xiaoping Yang, Amir Karger
Publikováno v:
Neuro-Oncology
The brain is the foremost non-gonadal tissue for expression of non-coding RNAs of unclear function. Yet, whether such transcripts are truly non-coding or rather the source of non-canonical protein translation is unknown. Here, we used functional geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07e7fb38fe9f9d7040af146960f85f8
http://europepmc.org/articles/PMC7715501
http://europepmc.org/articles/PMC7715501
Autor:
William C. Hahn, Aviad Tsherniak, Jesse S. Boehm, Francisca Vazquez, John M. Krill-Burger, Thomas M Green, Jordan Bryan, Guillaume Kugener, James M. McFarland, Todd R. Golub, Joshua M. Dempster, David E. Root, Zandra V. Ho, Phillip G. Montgomery
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
The availability of multiple datasets comprising genome-scale RNAi viability screens in hundreds of diverse cancer cell lines presents new opportunities for understanding cancer vulnerabilities. Integrated analyses of these data to assess differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e2e2e77e987d02e05195c1bd9da7df
Autor:
Michele Koonin, Thomas M. Green
Publikováno v:
Journal of Emotional Abuse. 4:71-79
Workplace violence, in its many forms, constitutes a form of abuse that affects the mental health of victims by creating stress that ultimately becomes overwhelming. One of the most difficult and debilitating aspects of workplace abuse is that the vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2a2e8142be585396c9f78fb27c906da
https://doi.org/10.1300/j135v04n03_05
https://doi.org/10.1300/j135v04n03_05
Autor:
Reza Fadaei‐Tehrani, Thomas M. Green
Publikováno v:
International Journal of Social Economics. 29:781-795
Theories of crime and delinquency tend to be discipline‐specific and are dominated by psychological, sociological, and economic approaches. The focus of this article will be on an economic approach to understanding criminal behavior and the design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7e28c39298af84e545c1ddb3c20d90f
https://doi.org/10.1108/03068290210444412
https://doi.org/10.1108/03068290210444412