Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Thomas M Coyne"'
Autor:
Elena Solopova, Wilber Romero-Fernandez, Hannah Harmsen, Lissa Ventura-Antunes, Emmeline Wang, Alena Shostak, Jose Maldonado, Manus J. Donahue, Daniel Schultz, Thomas M. Coyne, Andreas Charidimou, Matthew Schrag
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract We report the case of a 79-year-old woman with Alzheimer’s disease who participated in a Phase III randomized controlled trial called CLARITY-AD testing the experimental drug lecanemab. She was randomized to the placebo group and subsequen
Externí odkaz:
https://doaj.org/article/980393b02c7a4f79b9007c599dd91386
Autor:
Susanna P. Garamszegi, Daniel J. Brzostowicki, Thomas M. Coyne, Regina T. Vontell, David A. Davis
Publikováno v:
Toxins, Vol 16, Iss 1, p 42 (2024)
Cetaceans are well-regarded as sentinels for toxin exposure. Emerging studies suggest that cetaceans can also develop neuropathological changes associated with neurodegenerative disease. The occurrence of neuropathology makes cetaceans an ideal speci
Externí odkaz:
https://doaj.org/article/0938b2fa54f342818fc60f3a06c3d5d0
Autor:
David A. Davis, Susanna P. Garamszegi, Sandra Anne Banack, Patrick D. Dooley, Thomas M. Coyne, Dylan W. McLean, David S. Rotstein, Deborah C. Mash, Paul Alan Cox
Publikováno v:
Toxins, Vol 13, Iss 10, p 697 (2021)
Dolphins are well-regarded sentinels for toxin exposure and can bioaccumulate a cyanotoxin called β-N-methylamino-l-alanine (BMAA) that has been linked to human neurodegenerative disease. The same dolphins also possessed hallmarks of Alzheimer’s d
Externí odkaz:
https://doaj.org/article/7b23ae6f1e82409eae03d546c413000c
Autor:
David A Davis, Kiyo Mondo, Erica Stern, Ama K Annor, Susan J Murch, Thomas M Coyne, Larry E Brand, Misty E Niemeyer, Sarah Sharp, Walter G Bradley, Paul Alan Cox, Deborah C Mash
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213346 (2019)
Dolphin stranding events occur frequently in Florida and Massachusetts. Dolphins are an excellent sentinel species for toxin exposures in the marine environment. In this report we examine whether cyanobacterial neurotoxin, β-methylamino-L-alanine (B
Externí odkaz:
https://doaj.org/article/d8caefdf1ee341f08d8b8832c464c514
Autor:
Raj Nangunoori, J. Bruce Kneeland, Shih-Shan Lang, Eric L. Zager, Thomas M Coyne, Katherine L. Nathanson
Publikováno v:
Journal of Neurosurgery. 117:897-901
In recent literature, there have been case reports of an extremely rare entity characterized by hybrid peripheral nerve tumors consisting of elements of neurofibroma, schwannoma, and/or perineurioma. The authors present a unique case of a patient wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a456f66bca05259eab78d90d15ee0cc4
https://doi.org/10.3171/2012.8.jns111841
https://doi.org/10.3171/2012.8.jns111841
Autor:
Laurel Glaser, Thomas M. Coyne
Publikováno v:
Pathology Case Reviews. 16:256-259
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc1602b4ed06a9a1ef764fc2b6c2aa66
https://doi.org/10.1097/pcr.0b013e31823b826f
https://doi.org/10.1097/pcr.0b013e31823b826f
Publikováno v:
Journal of Cellular and Molecular Medicine
We have recently characterized a stem cell population isolated from the rodent amniotic membrane termed amnion-derived stem cells (ADSCs). In vitro ADSCs differentiate into cell types representing all three embryonic layers, including neural cells. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e239ee4b8630f6e2cafe15cbd5745e4d
https://doi.org/10.1111/j.1582-4934.2008.00180.x
https://doi.org/10.1111/j.1582-4934.2008.00180.x
Publikováno v:
Pharmacology & Toxicology. 87:211-217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0277ed43e95822f06e7d788f728bba44
https://doi.org/10.1034/j.1600-0773.2000.pto870504.x
https://doi.org/10.1034/j.1600-0773.2000.pto870504.x
Publikováno v:
Differentiation. 76:130-144
Stem-cell-based therapies may offer treatments for a variety of intractable diseases. A fundamental goal in stem-cell biology concerns the characterization of diverse populations that exhibit different potentials, growth capabilities, and therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aae05abee782312b6654cd3b9fc7bfc
https://doi.org/10.1111/j.1432-0436.2007.00194.x
https://doi.org/10.1111/j.1432-0436.2007.00194.x
Publikováno v:
The Journal of Neuroscience. 24:4585-4595
We recently differentiated adult rat and human bone marrow stromal cells (MSCs) into presumptive neurons in cell culture. To determine whether the MSCs assume neuronal functionsin vivo, we now characterize for the first time engraftment, migration, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc4b2bbfa59e540c8049cf35a4a9b1d
https://doi.org/10.1523/jneurosci.5060-03.2004
https://doi.org/10.1523/jneurosci.5060-03.2004