Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Thomas M Brodigan"'
Publikováno v:
Developmental Biology. 416:300-311
Spatial polarity cues in animals are used repeatedly during development for many processes, including cell fate determination, cell migration, and axon guidance. In Caenorhabditis elegans, the body wall muscle extends the length of the animal in four
Autor:
Thomas M. Brodigan, Michael W. Krause, David M. Eisenmann, Lakshmi Gorrepati, Margarita Correa-Mendez, Weiping Chen
Publikováno v:
G3: Genes|Genomes|Genetics
The evolutionarily conserved Wnt/β-catenin signaling pathway plays a fundamental role during metazoan development, regulating numerous processes including cell fate specification, cell migration, and stem cell renewal. Wnt ligand binding leads to st
Autor:
Brenda L. Bass, Thomas M Brodigan, Michael Krause, Leath A. Tonkin, Lisa Saccomanno, Daniel P. Morse
Publikováno v:
The EMBO Journal. 21:6025-6035
Here we take advantage of the well-characterized and simple nervous system of Caenorhabditis elegans to further our understanding of the functions of RNA editing. We describe the two C.elegans ADAR genes, adr-1 and adr-2, and characterize strains con
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25996 (2011)
PLoS ONE
PLoS ONE
Parasitic hookworms and the free-living model nematode Caenorhabtidis elegans share a developmental arrested stage, called the dauer stage in C. elegans and the infective third-stage larva (L3) in hookworms. One of the key transcription factors that
Autor:
Robert H. Waterston, Michael Krause, Lawrence A. Schriefer, Tetsunari Fukushige, Thomas M. Brodigan
Myogenic regulatory factors (MRFs) are required for mammalian skeletal myogenesis. In contrast, bodywall muscle is readily detectable in Caenorhabditis elegans embryos lacking activity of the lone MRF ortholog HLH-1, indicating that additional myogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfe666b795ae12ac5987bbf23e55d97
https://europepmc.org/articles/PMC1698447/
https://europepmc.org/articles/PMC1698447/
Autor:
Dona C. Love, Patrick T. Hennessey, Gilbert Ashwell, John A. Hanover, Thomas M Brodigan, Michele E. Forsythe, Michael Krause
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 102(32)
O-linked N -acetylglucosamine (O-GlcNAc) is an evolutionarily conserved modification of nuclear pore proteins, signaling kinases, and transcription factors. The O-GlcNAc transferase (OGT) catalyzing O-GlcNAc addition is essential in mammals and media
Publikováno v:
Development (Cambridge, England). 129(11)
Twist is a transcription factor that is required for mesodermal cell fates in all animals studied to date. Mutations of this locus in humans have been identified as the cause of the craniofacial disorder Saethre-Chotzen syndrome. The Caenorhabditis e
Publikováno v:
Developmental Biology. 344(1):503-504
Autor:
Michael Krause, Ann K Corsi, Daryl Dichoso, Joohong Ahnn, Reymond Llacer, Stephen A. Kostas, Andrew Fire, Thomas M Brodigan, Kyu Yeong Chwoe, Jin Sook Lee, Morgan Park
Publikováno v:
Developmental Biology. (2):431-440
MEF2 is an evolutionarily conserved MADS (MCM1, Agamous, Deficiens, and serum response factor) box-type transcription factor that plays a critical role in vertebrate and Drosophila melanogaster myogenesis. We have addressed the developmental role of
Publikováno v:
Developmental Biology. (1):102-115
Our interest in the coordination of cell cycle control and differentiation has led us to investigate the Caenorhabditis elegans cye-1 gene encoding the G1 cell cycle regulator cyclin E. We have studied the expression and function of cye-1 by using mo