Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Thomas M, Quinn"'
Solute Transport of Negatively Charged Contrast Agents Across Articular Surface of Injured Cartilage
Publikováno v:
Annals of Biomedical Engineering. 45:973-981
Solute transport through the extracellular matrix (ECM) is crucial to chondrocyte metabolism. Cartilage injury affects solute transport in cartilage due to alterations in ECM structure and solute-matrix interactions. Therefore, cartilage injury may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a168ec8e0e98c081fb92717d90d12c
https://doi.org/10.1007/s10439-016-1756-6
https://doi.org/10.1007/s10439-016-1756-6
Publikováno v:
Biophysical Journal. 107(2):485-492
Cartilage has a limited capacity for self-repair and focal damage can eventually lead to complete degradation of the tissue. Early diagnosis of degenerative changes in cartilage is therefore essential. Contrast agent-based computed tomography and mag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9dbb4be093f89cf63b574157e611ad
Publikováno v:
Archives of Biochemistry and Biophysics. 535:241-247
Solute transport through extracellular matrix (ECM) is important to physiology and contrast agent-based clinical imaging of articular cartilage. Mechanical injury is likely to have important effects on solute transport since it involves alteration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6215fdcd835beeb680f59c9cf1377846
https://doi.org/10.1016/j.abb.2013.04.011
https://doi.org/10.1016/j.abb.2013.04.011
Publikováno v:
Journal of Cellular and Molecular Medicine
Articular cartilage is an avascular tissue with poor regenerative capacity following injury, a contributing factor to joint degenerative disease. Cell-based therapies for cartilage tissue regeneration have rapidly advanced; however, expansion of auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ebc5b1ae0ef17b82d1fa5ca81dc3b5
https://doi.org/10.1111/jcmm.12034
https://doi.org/10.1111/jcmm.12034
Autor:
Monzur Murshed, Derek H. Rosenzweig, Jingjing Li, Ghazaleh Khayat, Zohreh Khavandgar, Thomas M. Quinn
Publikováno v:
ISRN Stem Cells. 2013:1-9
Mechanical stimulation influences stem cell differentiation and may therefore provide improved lineage specification control for clinical applications. Low-frequency oscillatory mechanical stimulation (0.01 Hz) has recently been shown to suppress adi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334bdb684ffd32d2933cb56677abd782
https://doi.org/10.1155/2013/138704
https://doi.org/10.1155/2013/138704
Autor:
Lok Shun Ko, Thomas M. Quinn
Publikováno v:
Biophysical Journal. 104(4):943-950
Electrolyte filtration arises due to the presence of fixed charges in cartilage extracellular matrix glycosaminoglycans (GAGs). Commonly assumed negligible, it can be important for design and interpretation of streaming potential measurements and mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f096f4db948d447b230b0690d96475d0
Publikováno v:
Annals of Biomedical Engineering. 41:894-903
Cartilage defects can be addressed with replacement strategies such as autologous chondrocyte implantation (ACI). Expansion of autologous chondrocytes in vitro is an essential step to obtain the necessary cell numbers required for ACI. A major proble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a18ea9a44f2517d63110617d0f95e4
https://doi.org/10.1007/s10439-012-0732-z
https://doi.org/10.1007/s10439-012-0732-z
Publikováno v:
Acta Biomaterialia. 9:4673-4680
Under conditions of free fluid flow, highly hydrated fibrillar collagen gels expel fluid and undergo gravity driven consolidation (self-compression; SC). This process can be accelerated by the application of a compressive stress (plastic compression;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1630fa8c7aea55dde4f36a8d448a3c16
https://doi.org/10.1016/j.actbio.2012.08.031
https://doi.org/10.1016/j.actbio.2012.08.031
Publikováno v:
Acta Biomaterialia. 8:3333-3341
Culture on silicone rubber surfaces has been shown to partially overcome the chondrocyte dedifferentiation characteristic of standard culture on rigid polystyrene. These methods typically involve functionalization of culture surfaces with proteins. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d689cf7b86b142201935dcc6251f668
https://doi.org/10.1016/j.actbio.2012.05.032
https://doi.org/10.1016/j.actbio.2012.05.032
Publikováno v:
McGill Science Undergraduate Research Journal. 7:42-48
Introduction: autologous chondrocyte implantation (aci) is one successful treatment for osteoarthritic defects (1-4). However, chondrocytes undergo a conversion to a fibroblastic phenotype during their expansion in vitro. This process can lead to deg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93b8e0b3434819d7f9ea7f653511372a
https://doi.org/10.26443/msurj.v7i1.102
https://doi.org/10.26443/msurj.v7i1.102