Figure S1. In Vivo Effects Of Oxaliplatin And Niclosamide On Mouse Motor Excitability from Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response

Autor: Carole Nicco, Frédéric Batteux, Bernard Weill, Nathaniel E.B. Saidu, Louis Marcellin, Pietro Santulli, Thomas Loussier, Niloufar Kavian, Romain Coriat, Marie-Anne Guillaumot, Florence Morin, Sandrine Chouzenoux, Christiane Chéreau, Evelyne Benoit, Olivier Cerles

Excitability waveforms (means {plus minus} SD) were recorded at the plantar muscle in response to motor sciatic nerve stimulation of mice treated for 5 weeks with vehicle (black circles, n = 6), oxaliplatin (white circles, n = 7), oxaliplatin plus ni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a540df57652b570e4e2a2f5feba25ef
https://doi.org/10.1158/1535-7163.22504294

Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response

Autor: Christiane Chéreau, Florence Morin, Pietro Santulli, Sandrine Chouzenoux, Niloufar Kavian, Thomas Loussier, Olivier Cerles, Carole Nicco, Evelyne Benoit, Marie-Anne Guillaumot, Bernard Weill, Louis Marcellin, Romain Coriat, Frédéric Batteux, Nathaniel Edward Bennett Saidu

Publikováno v: Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2017, 16 (2), pp.300-311. ⟨10.1158/1535-7163.MCT-16-0326⟩
Molecular Cancer Therapeutics, 2017, 16 (2), pp.300-311. ⟨10.1158/1535-7163.MCT-16-0326⟩

Neuropathic pain is a limiting factor of platinum-based chemotherapies. We sought to investigate the neuroprotective potential of niclosamide in peripheral neuropathies induced by oxaliplatin. Normal neuron-like and cancer cells were treated in vitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcebb471430151102e3e1586233a058a
https://hal-cea.archives-ouvertes.fr/cea-02121953/file/2017-MolCancerTherapeutics-OxaliPtNiclosamide.pdf