Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Thomas Lingner"'
Autor:
Tim Niklas Bewersdorf, Jakob Hofmann, Sebastian Findeisen, Christian Schamberger, Thomas Lingner, Ulrike Sommer, Gerhard Schmidmaier, Tobias Grossner
Publikováno v:
Antibiotics, Vol 13, Iss 2, p 186 (2024)
The treatment of fungal bone infections and infected non-unions is a huge challenge in modern trauma and orthopedics, which normally contain the local and systemic administration of anti-fungal drugs. Although frequently used, little is known about t
Externí odkaz:
https://doaj.org/article/2d261f1782314080b7502db2093e21ae
Autor:
Jakob Hofmann, Tim Niklas Bewersdorf, Ulrike Sommer, Thomas Lingner, Sebastian Findeisen, Christian Schamberger, Gerhard Schmidmaier, Tobias Großner
Publikováno v:
Antibiotics, Vol 13, Iss 1, p 44 (2024)
Antibiotic-loaded PMMA bone cement is frequently used in modern trauma and orthopedic surgery. Although many of the antibiotics routinely applied are described to have cytotoxic effects in the literature, clinical experience shows no adverse effects
Externí odkaz:
https://doaj.org/article/572a1d6385584ca9bd0f49a6078bdc79
Autor:
Giulia Treccani, Hatice Yigit, Thomas Lingner, Vanessa Schleuβner, Franziska Mey, Michael A. van der Kooij, Malin Wennström, David P. Herzog, Matthias Linke, Markus Fricke, Michael J. Schmeisser, Gregers Wegener, Thomas Mittmann, Jacqueline Trotter, Marianne B. Müller
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100338- (2021)
The precise mechanisms underlying the detrimental effects of early life adversity (ELA) on adult mental health remain still elusive. To date, most studies have exclusively targeted neuronal populations and not considered neuron-glia crosstalk as a cr
Externí odkaz:
https://doaj.org/article/d9eca5eca6cb4e2eae4d12198f50d25b
Autor:
Anne Hahn, Daniel Pensold, Cathrin Bayer, Jessica Tittelmeier, Lourdes González-Bermúdez, Lisa Marx-Blümel, Jenice Linde, Jonas Groß, Gabriela Salinas-Riester, Thomas Lingner, Julia von Maltzahn, Marc Spehr, Tomas Pieler, Anja Urbach, Geraldine Zimmer-Bensch
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Increased life expectancy in modern society comes at the cost of age-associated disabilities and diseases. Aged brains not only show reduced excitability and plasticity, but also a decline in inhibition. Age-associated defects in inhibitory circuits
Externí odkaz:
https://doaj.org/article/0f47d2d2087640479b08d94451253150
Autor:
Judit Meyer-Kovac, Isa Kolbe, Lea Ehrhardt, Alexei Leliavski, Jana Husse, Gabriela Salinas, Thomas Lingner, Anthony H. Tsang, Johanna L. Barclay, Henrik Oster
Publikováno v:
Molecular Metabolism, Vol 6, Iss 6, Pp 512-523 (2017)
Objective: Circadian Clock gene mutant mice show dampened 24-h feeding rhythms and an increased sensitivity to high-fat diet (HFD) feeding. Restricting HFD access to the dark phase counteracts its obesogenic effect in wild-type mice. The extent to wh
Externí odkaz:
https://doaj.org/article/5e09bdba51724f9db2bfc98b1ee085af
Autor:
Daniel Becker, Anna Greta Hirsch, Lysann Bender, Thomas Lingner, Gabriela Salinas, Heike Krebber
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3199-3214.e3 (2019)
Summary: Removal of introns from pre-mRNAs is an essential step in eukaryotic gene expression, mediated by spliceosomes that contain snRNAs as key components. Although snRNAs are transcribed in the nucleus and function in the same compartment, all ex
Externí odkaz:
https://doaj.org/article/9990dcb50b3c4e3cb5ffc0099916c3d1
Autor:
Pritesh Krishnakumar, Stephan Riemer, Roshan Perera, Thomas Lingner, Alexander Goloborodko, Hazem Khalifa, Franck Bontems, Felix Kaufholz, Mohamed A El-Brolosy, Roland Dosch
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007696 (2018)
The proteins Oskar (Osk) in Drosophila and Bucky ball (Buc) in zebrafish act as germ plasm organizers. Both proteins recapitulate germ plasm activities but seem to be unique to their animal groups. Here, we discover that Osk and Buc show similar acti
Externí odkaz:
https://doaj.org/article/3c93f30403ef4a9585bb2b75ac7857bb
Autor:
Stoyan Petkov, Tobias Kahland, Orr Shomroni, Thomas Lingner, Gabriela Salinas, Sigrid Fuchs, Katharina Debowski, Rüdiger Behr
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204580 (2018)
Following a certain type-specific number of mitotic divisions, terminally differentiated cells undergo proliferative senescence, thwarting efforts to expand different cell populations in vitro for the needs of scientific research or medical therapies
Externí odkaz:
https://doaj.org/article/0469f850feed43149eb586dead3c3867
Autor:
Nicole Kohrs, Stephan Kolodziej, Olga N Kuvardina, Julia Herglotz, Jasmin Yillah, Stefanie Herkt, Alexander Piechatzek, Gabriela Salinas Riester, Thomas Lingner, Christian Wichmann, Halvard Bonig, Erhard Seifried, Uwe Platzbecker, Hind Medyouf, Manuel Grez, Jörn Lausen
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005946 (2016)
A network of lineage-specific transcription factors and microRNAs tightly regulates differentiation of hematopoietic stem cells along the distinct lineages. Deregulation of this regulatory network contributes to impaired lineage fidelity and leukemog
Externí odkaz:
https://doaj.org/article/d02eb5eaf4d447fa9f41d6ae5dba62e1
Autor:
Julia Hofhuis, Fabian Schueren, Christopher Nötzel, Thomas Lingner, Jutta Gärtner, Olaf Jahn, Sven Thoms
Publikováno v:
Open Biology, Vol 6, Iss 11 (2016)
Translational readthrough gives rise to C-terminally extended proteins, thereby providing the cell with new protein isoforms. These may have different properties from the parental proteins if the extensions contain functional domains. While for most
Externí odkaz:
https://doaj.org/article/03aca3f59666453abc0d56dffde762a7