Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Thomas Lindhorst"'
Autor:
Gerlinde Doenz, Sebastian Dorn, Narges Aghaallaei, Baubak Bajoghli, Elisabeth Riegel, Michaela Aigner, Holger Bock, Birgit Werner, Thomas Lindhorst, Thomas Czerny
Publikováno v:
BMC Biotechnology, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background The application of antisense molecules, such as morpholino oligonucleotides, is an efficient method of gene inactivation in vivo. We recently introduced phosphonic ester modified peptide nucleic acids (PNA) for in vivo loss-of-fun
Externí odkaz:
https://doaj.org/article/ebcc5c44420f40ddbd3a7bce3da58446
Autor:
Elisabeth Riegel, Holger Bock, Matthias Vonbrüll, Thomas Czerny, Thomas Lindhorst, Christian Halter, Birgit Werner, Michaela Aigner
Publikováno v:
Molecular Biotechnology
There have been many attempts to unveil the therapeutic potential of antisense molecules during the last decade. Due to its specific role in canonical Wnt signalling, β-catenin is a potential target for an antisense-based antitumour therapy. In orde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f7eeb3ac73a4b7fc9885493950b284
https://doi.org/10.1007/s12033-018-0058-7
https://doi.org/10.1007/s12033-018-0058-7
Autor:
Michaela Aigner, Sebastian Dorn, Baubak Bajoghli, Elisabeth Riegel, Holger Bock, Birgit Werner, Thomas Lindhorst, Narges Aghaallaei, Thomas Czerny, Gerlinde Doenz
Publikováno v:
BMC Biotechnology, Vol 18, Iss 1, Pp 1-14 (2018)
BMC Biotechnology
BMC Biotechnology
Background The application of antisense molecules, such as morpholino oligonucleotides, is an efficient method of gene inactivation in vivo. We recently introduced phosphonic ester modified peptide nucleic acids (PNA) for in vivo loss-of-function exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3599277a6e1e0cfc56811727ed705cc2
http://archiv.ub.uni-heidelberg.de/volltextserver/24277/
http://archiv.ub.uni-heidelberg.de/volltextserver/24277/
Autor:
Cornelia Lass-Flörl, Holger Bock, Thomas Lindhorst, Stefan Piper, Birgit Werner, Doris Wilflingseder, Wilfried Posch, Adam J. Fletcher, Heribert Stoiber
Publikováno v:
Molecular Medicine. 18:111-122
Although rapidly becoming a valuable tool for gene silencing, regulation or editing in vitro, the direct transfer of small interfering ribonucleic acids (siRNAs) into cells is still an unsolved problem for in vivo applications. For the first time, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812c1babf596730e39bb54da9c78f2b8
https://doi.org/10.2119/molmed.2011.00128
https://doi.org/10.2119/molmed.2011.00128
Autor:
Otto Hudecz, Michael Mazanek, Thomas Lindhorst, David Teis, Oliver A. Wrulich, Elisabeth Roitinger, Thomas Taus, Lukas A. Huber, Karin Grosstessner-Hain, Sandra Morandell, Karl Mechtler, Florian Ueberall
Publikováno v:
PROTEOMICS. 10:2015-2025
Signaling networks regulate cellular responses to external stimuli through post-translational modifications such as protein phosphorylation. Phosphoproteomics facilitate the large-scale identification of kinase substrates. Yet, the characterization o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa53bdb8ea401a8b031f3d43e802ce4
https://doi.org/10.1002/pmic.200900749
https://doi.org/10.1002/pmic.200900749
Publikováno v:
ChemInform. 30
The synthesis of a new class of isocyanides and its application in the Ugi reaction is described. Ugi products derived from (β-isocyano-ethyl)-alkyl-carbonates can be converted to N-acylated α-amino acids and esters under mild basic conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::deafabd07870c44ba9c486cfd6415ecb
https://doi.org/10.1002/chin.199939076
https://doi.org/10.1002/chin.199939076
Autor:
Thomas Czerny, Birgit Werner, Thomas Lindhorst, Baubak Bajoghli, Gerlinde Jung, Sebastian Dorn, Holger Bock, Narges Aghaallaei
Publikováno v:
BMC Biotechnology
BMC Biotechnology, Vol 12, Iss 1, p 50 (2012)
BMC Biotechnology, Vol 12, Iss 1, p 50 (2012)
BackgroundSynthetic antisense molecules have an enormous potential for therapeutic applications in humans. The major aim of such strategies is to specifically interfere with gene function, thus modulating cellular pathways according to the therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83420b513746723a73e35bb4ea1de628