Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Thomas Levin, Andersen"'
Autor:
Aric Anloague, Hayley M. Sabol, Japneet Kaur, Sharmin Khan, Cody Ashby, Carolina Schinke, C. Lowry Barnes, Farah Alturkmani, Elena Ambrogini, Michael Tveden Gundesen, Thomas Lund, Anne Kristine Amstrup, Thomas Levin Andersen, Marta Diaz-delCastillo, G. David Roodman, Teresita Bellido, Jesus Delgado-Calle
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Multiple myeloma (MM) is a clonal plasma cell proliferative malignancy characterized by a debilitating bone disease. Osteolytic destruction, a hallmark of MM, is driven by increased osteoclast number and exacerbated bone resorption, primarily fueled
Externí odkaz:
https://doaj.org/article/2cc6d4c16ea547a48e641d7a171fc618
Autor:
Søren Reinhold Jakobsen, Marta Diaz-delCastillo, Martin Blomberg Jensen, Thomas Levin Andersen, Ebbe Eldrup, Trine Skov Nielsen
Publikováno v:
Bone Reports, Vol 20, Iss , Pp 101749- (2024)
In this forensic case report, we present autopsy findings from a young male in his thirties who had been self-injecting paraffin oil into his upper extremities 8 years prior to death. The injections induced an inflammatory response, leading to granul
Externí odkaz:
https://doaj.org/article/65bae80e1b3e4ad0bd80e46a4f9570be
Autor:
Pernille vanDijk Christiansen, Tanja Sikjær, Christina Møller Andreasen, Jesper Skovhus Thomsen, Annemarie Brüel, Ellen Margrethe Hauge, Jean‐Marie Delaisse, Lars Rejnmark, Thomas Levin Andersen
Publikováno v:
JBMR Plus, Vol 7, Iss 12, Pp n/a-n/a (2023)
ABSTRACT In hypoparathyroidism, lack of parathyroid hormone (PTH) leads to low calcium levels and decreased bone remodeling. Treatment with recombinant human PTH (rhPTH) may normalize bone turnover. This study aimed to investigate whether rhPTH(1–8
Externí odkaz:
https://doaj.org/article/577b8c5a0d184c0aaba5bc2ca3f82332
Autor:
Louise Alstrup Drejer, Bilal Mohamad El-Masri, Charlotte Ejersted, Christina Møller Andreasen, Lisbeth Koch Thomsen, Jesper Skovhus Thomsen, Thomas Levin Andersen, Stinus Hansen
Publikováno v:
Bone Reports, Vol 19, Iss , Pp 101703- (2023)
Background: Denosumab, is a potent anti-resorptive that, increases bone mineral density, and reduces fracture risk in osteoporotic patients. However, several case studies have reported multiple vertebral fractures in patients discontinuing denosumab.
Externí odkaz:
https://doaj.org/article/371d1edcb9ad41ac8ac78ce0965d0bac
Autor:
Li Chen, Kaikai Shi, Nicholas Ditzel, Weimin Qiu, Florence Figeac, Louise Himmelstrup Dreyer Nielsen, Michaela Tencerova, Justyna Magdalena Kowal, Ming Ding, Christina Møller Andreasen, Thomas Levin Andersen, Moustapha Kassem
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Upon transplantation, skeletal stem cells (also known as bone marrow stromal or mesenchymal stem cells) can regulate bone regeneration by producing secreted factors. Here, we identify KIAA1199 as a bone marrow stromal cell-secreted factor in
Externí odkaz:
https://doaj.org/article/3efdbe51f9204b0f9ca4735335ff754a
Autor:
Christopher W Fell, Astrid Hagelkruys, Ana Cicvaric, Marion Horrer, Lucy Liu, Joshua Shing Shun Li, Johannes Stadlmann, Anton A Polyansky, Stefan Mereiter, Miguel Angel Tejada, Tomislav Kokotović, Venkat Swaroop Achuta, Angelica Scaramuzza, Kimberly A Twyman, Michelle M Morrow, Jane Juusola, Huifang Yan, Jingmin Wang, Margit Burmeister, Biswa Choudhury, Thomas Levin Andersen, Gerald Wirnsberger, Uffe Holmskov, Norbert Perrimon, Bojan Žagrović, Francisco J Monje, Jesper Bonnet Moeller, Josef M Penninger, Vanja Nagy
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 9, Pp 1-23 (2022)
Abstract Whole‐exome sequencing of two patients with idiopathic complex neurodevelopmental disorder (NDD) identified biallelic variants of unknown significance within FIBCD1, encoding an endocytic acetyl group‐binding transmembrane receptor with
Externí odkaz:
https://doaj.org/article/97ff532b47a541dcbc19af3c49df7a36
Autor:
Karin H. Nilsson, Petra Henning, Maha El Shahawy, Maria Nethander, Thomas Levin Andersen, Charlotte Ejersted, Jianyao Wu, Karin L. Gustafsson, Antti Koskela, Juha Tuukkanen, Pedro P. C. Souza, Jan Tuckermann, Mattias Lorentzon, Linda Engström Ruud, Terho Lehtimäki, Jon H. Tobias, Sirui Zhou, Ulf H. Lerner, J. Brent Richards, Sofia Movérare-Skrtic, Claes Ohlsson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Genetic association signals for fractures have been reported at the RSPO3 locus, but the causal gene and the underlying mechanism are unknown. Here, the authors show that RSPO3 exerts an important role for vertebral trabecular bone mass and bone stre
Externí odkaz:
https://doaj.org/article/bb0475854da041a2990d5eeb48bf5cee
Autor:
Stephanie Lucas, Michaela Tencerova, Benoit von der Weid, Thomas Levin Andersen, Camille Attané, Friederike Behler-Janbeck, William P. Cawthorn, Kaisa K. Ivaska, Olaia Naveiras, Izabela Podgorski, Michaela R. Reagan, Bram C. J. van der Eerden
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Over the last two decades, increased interest of scientists to study bone marrow adiposity (BMA) in relation to bone and adipose tissue physiology has expanded the number of publications using different sources of bone marrow adipose tissue (BMAT). H
Externí odkaz:
https://doaj.org/article/70674b54510942529567cd8bfc58493e
Autor:
Megan M. Weivoda, Chee Kian Chew, David G. Monroe, Joshua N. Farr, Elizabeth J. Atkinson, Jennifer R. Geske, Brittany Eckhardt, Brianne Thicke, Ming Ruan, Amanda J. Tweed, Louise K. McCready, Robert A. Rizza, Aleksey Matveyenko, Moustapha Kassem, Thomas Levin Andersen, Adrian Vella, Matthew T. Drake, Bart L. Clarke, Merry Jo Oursler, Sundeep Khosla
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Anti-resorptive bone therapies also inhibit bone formation, as osteoclasts secrete factors that stimulate bone formation by osteoblasts. Here, the authors identify osteoclast-secreted factors that couple bone resorption to bone formation in healthy s
Externí odkaz:
https://doaj.org/article/801d47b97fd94e109d4d6b51b08d8de3
Autor:
Liviu-Ionut Moldovan, Thomas Birkballe Hansen, Morten Trillingsgaard Venø, Trine Line Hauge Okholm, Thomas Levin Andersen, Henrik Hager, Lars Iversen, Jørgen Kjems, Claus Johansen, Lasse Sommer Kristensen
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-17 (2019)
Abstract Background Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation and abnormal differentiation of keratinocytes. It is one of the most prevalent chronic inflammatory skin conditions in adults worldwide, with a c
Externí odkaz:
https://doaj.org/article/e128b91bc28446c18746bdc4ef495a04