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pro vyhledávání: '"Thomas Legier"'
Autor:
Thomas Legier, Diane Rattier, Jack Llewellyn, Thomas Vannier, Benoit Sorre, Flavio Maina, Rosanna Dono
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Fate specification in the mammalian epiblast rely on complex interactions between morphogens and tissue organization. Here, the authors highlight epithelial integrity as a key determinant of TGF-β activity and a mechanism guiding morphogen sensing a
Externí odkaz:
https://doaj.org/article/52bebb16053b49cabec655895f138a68
Autor:
Serena Corti, Remi Bonjean, Thomas Legier, Diane Rattier, Christophe Melon, Pascal Salin, Erik A. Toso, Michael Kyba, Lydia Kerkerian‐Le Goff, Flavio Maina, Rosanna Dono
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 5, Pp 725-742 (2021)
Abstract Enhancing the differentiation potential of human induced pluripotent stem cells (hiPSC) into disease‐relevant cell types is instrumental for their widespread application in medicine. Here, we show that hiPSCs downregulated for the signalin
Externí odkaz:
https://doaj.org/article/c49417db6b2e497583d507f331d2646d
The processes of primitive streak formation and fate specification in the mammalian epiblast rely on complex interactions between morphogens and tissue organization. Little is known about how these instructive cues functionally interact to regulate g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cf8221de3f24f91a99942383c70acb
https://doi.org/10.1101/2021.10.22.465459
https://doi.org/10.1101/2021.10.22.465459