Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Thomas Le Bihan"'
Publikováno v:
European Journal of Organic Chemistry. 2019:5955-5962
Autor:
Alain Faivre-Chauvet, Raphaël Tripier, Nathalie Le Bris, Thomas Le Bihan, Patricia Le Saëc, Mickaël Bourgeois, Clément Bailly, Catherine Saï-Maurel, Michel Chérel, Anne-Sophie Navarro
Publikováno v:
Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, 2019, ⟨10.1021/acs.bioconjchem.9b00510⟩
Bioconjugate Chemistry, 2019, ⟨10.1021/acs.bioconjchem.9b00510⟩
Bioconjugate Chemistry, American Chemical Society, 2019, ⟨10.1021/acs.bioconjchem.9b00510⟩
Bioconjugate Chemistry, 2019, ⟨10.1021/acs.bioconjchem.9b00510⟩
Following the successful synthesis of a C-functionalized version of the TE1PA ligand, a monopicolinate cyclam, we looked to demonstrate its in vivo properties versus DOTA and NOTA, after conjugation on the 9E7.4 rat antibody, an IgG2a against CD138 m
Autor:
Richard C, Knighton, Thibault, Troadec, Valérie, Mazan, Patricia, Le Saëc, Séverine, Marionneau-Lambot, Thomas, Le Bihan, Nathalie, Saffon-Merceron, Nathalie, Le Bris, Michel, Chérel, Alain, Faivre-Chauvet, Mourad, Elhabiri, Loïc J, Charbonnière, Raphaël, Tripier
Publikováno v:
Inorganic chemistry. 60(4)
Herein we present the preparation of two novel cyclam-based macrocycles (
Autor:
Richard Knighton, Thibault Troadec, Valerie Mazan, Patricia Le Saëc, Séverine Marionneau-Lambot, Thomas Le Bihan, Nathalie Saffon-Merceron, Nathalie Le Bris, Michel Chérel, Alain Faivre-Chauvet, Mourad Elhabiri, Loïc J. Charbonnière, Raphael Tripier
Herein we present the preparation of two novel cyclam-based macrocycles (te1pyp and cb-te1pyp), bearing phosphonate-appended pyridine side-arms for the coordination of copper(II) ions in the context of 64Cu PET imaging. The two ligands have been prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07abfdf20038215bdbfae48c491c75dd
https://hal.univ-brest.fr/hal-03093634
https://hal.univ-brest.fr/hal-03093634
Autor:
Séverine Marionneau-Lambot, Nathalie Saffon-Merceron, Michel Chérel, Mourad Elhabiri, Valérie Mazan, Nathalie Le Bris, Richard C. Knighton, Loïc J. Charbonnière, Thibault Troadec, Thomas Le Bihan, Patricia Le Saëc, Raphaël Tripier, Alain Faivre-Chauvet
Publikováno v:
Inorganic Chemistry
Inorganic Chemistry, American Chemical Society, 2021, 60 (4), pp.2634-2648. ⟨10.1021/acs.inorgchem.0c03492⟩
Inorganic Chemistry, 2021, 60 (4), pp.2634-2648. ⟨10.1021/acs.inorgchem.0c03492⟩
Inorganic Chemistry, American Chemical Society, 2021, 60 (4), pp.2634-2648. ⟨10.1021/acs.inorgchem.0c03492⟩
Inorganic Chemistry, 2021, 60 (4), pp.2634-2648. ⟨10.1021/acs.inorgchem.0c03492⟩
International audience; Herein we present the preparation of two novel cyclam-based macrocycles (te1pyp and cb-te1pyp), bearing phosphonate-appended pyridine side arms for the coordination of copper(II) ions in the context of 64Cu PET imaging. The tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4677ff7448f53aab67fbe65d105738e8
https://hal.archives-ouvertes.fr/hal-03123032
https://hal.archives-ouvertes.fr/hal-03123032
Autor:
Thomas, Le Bihan, Cathryn H S, Driver, Thomas, Ebenhan, Nathalie, Le Bris, Jan Rijn, Zeevaart, Raphaël, Tripier
Publikováno v:
ChemMedChem. 16(5)
An improved glucose-chelator-albumin bioconjugate (GluCAB) derivative, GluCAB-2
Autor:
Thomas Le Bihan, Cathryn H.S. Driver, Thomas Ebenhan, Nathalie Le Bris, Jan Rijn Zeevaart, Raphael Tripier
In the aim to design small molecules capable of binding in vivo to albumin to form bioconjugates, a second generation GluCAB derivative(Glucose-Chelator-Albumin Bioconjugate) has been synthesized and studied for in vivo 64Cu-PET/CT imaging in breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6751ad1473305eafee44867b50e0bff8
https://doi.org/10.26434/chemrxiv.12708608.v1
https://doi.org/10.26434/chemrxiv.12708608.v1
Autor:
Thomas Le Bihan, Cathryn H.S. Driver, Raphaël Tripier, Thomas Ebenhan, Nathalie Le Bris, Jan Rijn Zeevaart
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2020, ⟨10.1002/cmdc.202000800⟩
ChemMedChem, Wiley-VCH Verlag, 2020, ⟨10.1002/cmdc.202000800⟩
International audience; An improved glucose‐chelator‐albumin bioconjugate (GluCAB) derivative, GluCAB‐2Mal, has been synthesized and studied for in vivo 64Cu‐PET/CT imaging in breast cancer mice models together with its first‐generation ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112b69876834d41c4eb09bae4007a7b0
https://hal.univ-brest.fr/hal-03079054
https://hal.univ-brest.fr/hal-03079054
Autor:
Anne-Sophie, Navarro, Thomas, Le Bihan, Patricia, Le Saëc, Nathalie Le, Bris, Clément, Bailly, Catherine, Saï-Maurel, Mickaël, Bourgeois, Michel, Chérel, Raphaël, Tripier, Alain, Faivre-Chauvet
Publikováno v:
Bioconjugate chemistry. 30(9)
Following the successful synthesis of a
Autor:
Thomas, Le Bihan, Anne-Sophie, Navarro, Nathalie, Le Bris, Patricia, Le Saëc, Sébastien, Gouard, Ferid, Haddad, Jean-François, Gestin, Michel, Chérel, Alain, Faivre-Chauvet, Raphaël, Tripier
Publikováno v:
Organicbiomolecular chemistry. 16(23)
In view of the excellent copper(ii) and 64-copper(ii) complexation of a TE1PA ligand, a monopicolinate cyclam, in both aqueous medium and in vivo, we looked for a way to make it bifunctional, while maintaining its chelating properties. Overcoming the