Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Thomas L. Tarnowski"'
Autor:
Yuan Shek Chen, Thomas L. Tarnowski, Kah Hiing John Ling, Jasper Chu, Eric van Ingen, Rita Humeniuk, Polina German, Deqing Xiao, Anita Mathias
Publikováno v:
Analytical Biochemistry
Remdesivir (RDV) is a phosphoramidate prodrug designed to have activity against a broad spectrum of viruses. Following IV administration, RDV is rapidly distributed into cells and tissues and simultaneously metabolized into GS-441524 and GS-704277 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0d5d7ac0f4949459d9cd374b318d35
https://pubmed.ncbi.nlm.nih.gov/33508271
https://pubmed.ncbi.nlm.nih.gov/33508271
Autor:
Yuan-Shek Chen, Tianyi zhang, Lili Ma, Kah Hiing John Ling, Yuwen Zhao, Brian P. Kearney, Sophia Majeed, Polina German, Thomas L. Tarnowski, Deqing Xiao
Publikováno v:
Analytical biochemistry. 593
Tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) are both tenofovir (TFV) prodrugs, with the same active intracellular metabolite, TFV-diphosphate (TFV-DP). TAF delivers TFV-DP to target cells more efficiently and at lower doses th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18284ca84a1b71512440d33ba75fe6a3
https://pubmed.ncbi.nlm.nih.gov/32035040
https://pubmed.ncbi.nlm.nih.gov/32035040
Autor:
Thomas L. Tarnowski, Susan Zondlo, Sophia R. Majeed, Deqing Xiao, Brian Kearney, Kah Hiing John Ling, Christos Kolaris
Publikováno v:
Analytical biochemistry. 585
A fluorescent quantitation method to determine PBMC-derived DNA amounts using purified human genomic DNA (gDNA) as the reference standard was developed and validated. gDNA was measured in a fluorescence-based assay using a DNA intercalant, SYBR green
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d218a22527c2aecb45322f14bd2988cd
https://pubmed.ncbi.nlm.nih.gov/31437427
https://pubmed.ncbi.nlm.nih.gov/31437427
Autor:
Robert Raschke, Albert Dorr, James D. Hulse, Robert E. Kates, Kay Griffy, Donald Jung, Thomas L. Tarnowski
Publikováno v:
The Journal of Clinical Pharmacology. 38:1057-1062
This study was designed to investigate the interaction between high-dose oral ganciclovir (6,000 mg/day) and didanosine at steady state in patients who were seropositive for human immunodeficiency virus (HIV) and cytomegalovirus (CMV) infection. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5346f82b049b0a1b2c41a89e17606a2f
https://doi.org/10.1177/009127009803801111
https://doi.org/10.1177/009127009803801111
Autor:
James Lavelle, Cimoch Pj, Donald Jung, Thomas L. Tarnowski, Kay Griffy, Sandra Casserella, Richard B. Pollard, Rodney Wong
Publikováno v:
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association. 17(3)
The aim of this study was to determine whether oral ganciclovir interacted pharmacokinetically with zidovudine (AZT), didanosine (ddI), or probenecid. A multicenter, open-label, randomized, crossover pharmacokinetic study with four phases was underta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc14932e3a38fbbfae436969d8fbca0
https://pubmed.ncbi.nlm.nih.gov/9495222
https://pubmed.ncbi.nlm.nih.gov/9495222
Autor:
Thomas L. Tarnowski, John L. Toner, James M. Mayer, Roger C. Helgeson, Donald J. Cram, Y. Chao, Gary R. Weisman
Publikováno v:
Journal of the American Chemical Society. 101:4928-4941
Syntheses are reported for 16 new macrocyclic polyether ligand systems which contain potentially convergent side chains containing additional binding sites. The free energies of association of these systems in CDCl/sub 3/ at 25/sup 0/C with Li/sup +/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd02040290af2b0c41f699aa4a024004
https://doi.org/10.1021/ja00511a024
https://doi.org/10.1021/ja00511a024
Autor:
Stephen S. Moore, Evan P. Kyba, Khorshed Madan, Roger C. Helgeson, Donald J. Cram, George W. Gokel, Thomas L. Tarnowski
Publikováno v:
Journal of the American Chemical Society. 99:2564-2571
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7d88b6717f4b123f5db7729a73ddc82
https://doi.org/10.1021/ja00450a026
https://doi.org/10.1021/ja00450a026
Publikováno v:
The Journal of Organic Chemistry. 44:2538-2550
Eighteen new macrocyclic polyethers are described, many of which are multistranded. The free energies of complexation in COCl/sub 3/ at 25/sup 0/C of these hosts with Li/sup +/, Na/sup +/, K/sup +/, Rb/sup +/, Cs/sup +/, and NH/sub 4//sup +/ picrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f7acf70945bdafa4c236974a97c41a7
https://doi.org/10.1021/jo01328a045
https://doi.org/10.1021/jo01328a045
Publikováno v:
Journal of the American Chemical Society. 99:6398-6405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f7341f82daa0f89057bf103db69931
https://doi.org/10.1021/ja00461a036
https://doi.org/10.1021/ja00461a036
Publikováno v:
Analytical Biochemistry. 146:211-219
A new highly sensitive nonseparation enzyme immunoassay for human serum ferritin is described. Reagents include a β-galactosidase-ferritin conjugate, sheep anti-ferritin, anti-sheep IgG, and dextran-linked β-galactosylumbelliferone as enzyme substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690ccc10148339a28eb888a498858338
https://doi.org/10.1016/0003-2697(85)90418-x
https://doi.org/10.1016/0003-2697(85)90418-x