Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Thomas L. Mcdonald"'
Autor:
Robert N. Cole, C. Conover Talbot, George H. Sack, Thomas L. McDonald, Nadine Rosenblum, Natasha E. Zachara, Simion Kreimer
Publikováno v:
FEBS Open Bio
Proteins of the serum amyloid A (SAA) family have been remarkably conserved in evolution. Their biologic function(s) are not fully defined but they are likely to be a part of primordial host defense. We have detected a ∼ 12-kDa protein reacting wit
Publikováno v:
Nutrients, Vol 13, Iss 751, p 751 (2021)
Nutrients
Nutrients
The use of dietary supplements has become increasingly common over the past 20 years. Whereas supplements were formerly used mainly by elite athletes, age and fitness status no longer dictates who uses these substances. Indeed, many nutritional suppl
Autor:
Xian Ming Chen, Stephanie W. Holzmer, Steven Tracy, Yang Wang, Lisa A. Riesberg, Kristen M. Drescher, Thomas L. McDonald
Publikováno v:
Cytokine. 110
Creatinine is the breakdown product of creatine, a key participant in the generation of ATP and is traditionally considered to be a biologically inert waste product. Based on our earlier work, we analyzed the effects of creatinine hydrochloride on th
Publikováno v:
Journal of Microbiological Methods. 105:155-161
Creatinine (CRN) is a vertebrate metabolic waste product normally found in blood and urine. Previous work demonstrated that the hydrochloride salt of creatinine (CRN-HCl) acted as a potent inhibitor of bacterial replication. Creatinine hydrochloride
Autor:
Joan M. Eckerson, Thomas L. McDonald, Lisa A. Riesberg, Kristen M. Drescher, Stephanie A. Weed
Creatine is widely used by both elite and recreational athletes as an ergogenic aid to enhance anaerobic exercise performance. Older individuals also use creatine to prevent sarcopenia and, accordingly, may have therapeutic benefits for muscle wastin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e37b8c725f6117ad92db3d37686586
https://europepmc.org/articles/PMC4915971/
https://europepmc.org/articles/PMC4915971/
Autor:
Pat G. Casey, Colin Hill, Annika Weber, Michael Cronin, Sarah O'Flaherty, Thomas L. McDonald, R.P. Ross, Cormac G. M. Gahan, Fergus Shanahan, Gillian E. Gardiner
Publikováno v:
FEMS Immunology & Medical Microbiology. 55:404-413
In vitro experiments confirmed that a 10-mer peptide derived from human mammary-associated serum amyloid A3 (M-SAA3) protected intestinal epithelial cells from enteropathogenic Escherichia coli (EPEC) adherence. The entire 42-mer human M-SAA3 protein
Publikováno v:
Veterinary Immunology and Immunopathology. 109:79-83
Mastitis is one of the most costly diseases of agriculturally important animals and is a common problem for lactating cows. Current methods used to detect clinical and especially subclinical mastitis are either inadequate or problematic. Pathogens su
Induction of human mammary-associated serum amyloid A3 expression by prolactin or lipopolysaccharide
Publikováno v:
Biochemical and Biophysical Research Communications. 301:1030-1037
In most mammalian species, serum amyloid A isoform 3 (SAA3) appears to be the predominant SAA isoform expressed extrahepatically. However, human SAA3 gene expression has not been detected previously and, therefore, this gene was referred to as a pseu
Publikováno v:
Biochemical and Biophysical Research Communications. 300:531-540
We previously determined that the N-terminal region of bovine mammary-associated serum amyloid A3 (M-SAA3) increased intestinal mucin MUC3 levels in HT29 human intestinal cells by approximately 2.5-fold, relative to untreated cells. This study shows
Publikováno v:
Veterinary Immunology and Immunopathology. 83:203-211
Mammary-associated serum amyloid A 3 (M-SAA3) was secreted at highly elevated levels in bovine, equine and ovine colostrum and found at lower levels in milk 4 days postparturition. N-terminal sequencing of the mature M-SAA3 protein from all the three