Výsledky vyhledávání - "Thomas L. Kandl"

Supplementary Figure 1 from Distinct Biological Types of Ocular Adnexal Sebaceous Carcinoma: HPV-Driven and Virus-Negative Tumors Arise through Nonoverlapping Molecular-Genetic Alterations

Autor: Bita Esmaeli, Anna Yemelyanova, Victor G. Prieto, Kenna Shaw, Agda Karina Eterovic, Ken Chen, Tae-Boom Kim, Doina Ivan, Courtney W. Hudgens, Mark Routbort, Diana Bell, Bo Peng, Thomas L. Kandl, Oded Sagiv, Jing Ning, Jonathan L. Curry, Michael T. Tetzlaff

Supplemental Figure 1. Representative images of nuclear grade. Histopathologic grade was defined according to the nuclear morphology and cytoplasmic evidence of sebaceous differentiation comprising the predominance (>50%) of the tumor cells. (A) High

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c87f03c062c3864bc8f4cf27c7ca52
https://doi.org/10.1158/1078-0432.22468274

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Supplementary Table 2 from Distinct Biological Types of Ocular Adnexal Sebaceous Carcinoma: HPV-Driven and Virus-Negative Tumors Arise through Nonoverlapping Molecular-Genetic Alterations

Supplementary Table 2. Mean per sample coverage information.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5990cbea5c5f10454cfce7769aba9df9
https://doi.org/10.1158/1078-0432.22468268

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Supplementary Table 3 from Distinct Biological Types of Ocular Adnexal Sebaceous Carcinoma: HPV-Driven and Virus-Negative Tumors Arise through Nonoverlapping Molecular-Genetic Alterations

Supplemental Table 3. Summary of TP53 and RB1 mutational status, immunohistochemical detection of TP53 and RB and histopathologic features in primary/locally recurrent ocular adnexal (OA) sebaceous carcinomas.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ee1c4ed9659ece41684e476ae3bcc9
https://doi.org/10.1158/1078-0432.22468265.v1

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Supplementary Table 1 from Distinct Biological Types of Ocular Adnexal Sebaceous Carcinoma: HPV-Driven and Virus-Negative Tumors Arise through Nonoverlapping Molecular-Genetic Alterations

Supplementary Table 1. Summary of mutations identified in the entire cohort of primary, locally recurrent and metastatic tumors.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d2e16fb3b7377cb2936443ffc4b4ec
https://doi.org/10.1158/1078-0432.22468271.v1

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Supplementary Table 4 from Distinct Biological Types of Ocular Adnexal Sebaceous Carcinoma: HPV-Driven and Virus-Negative Tumors Arise through Nonoverlapping Molecular-Genetic Alterations

Supplemental Table 4. Fisher's exact test to determine associations between the presence of specific mutations and histopathologic phenotypes in ocular adnexal sebaceous carcinomas.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cadc5c8650b0dffcba74761dfff064cb
https://doi.org/10.1158/1078-0432.22468262

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Data from Distinct Biological Types of Ocular Adnexal Sebaceous Carcinoma: HPV-Driven and Virus-Negative Tumors Arise through Nonoverlapping Molecular-Genetic Alterations

Purpose:Ocular adnexal (OA) sebaceous carcinoma is an aggressive malignancy of the eyelid and ocular adnexa that frequently recurs and metastasizes, and effective therapies beyond surgical excision are lacking. There remains a critical need to define

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d4951ba505ed33f93ca186446352c7
https://doi.org/10.1158/1078-0432.c.6526880

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