Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Thomas L. Gallagher"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-33 (2024)
Abstract Adeno-associated virus (AAV) has emerged as a pivotal delivery tool in clinical gene therapy owing to its minimal pathogenicity and ability to establish long-term gene expression in different tissues. Recombinant AAV (rAAV) has been engineer
Externí odkaz:
https://doaj.org/article/0d352d9c4b0c45b6a1cdc849a6677099
Autor:
Pooja Gangras, Thomas L Gallagher, Michael A Parthun, Zhongxia Yi, Robert D Patton, Kiel T Tietz, Natalie C Deans, Ralf Bundschuh, Sharon L Amacher, Guramrit Singh
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008830 (2020)
Many post-transcriptional mechanisms operate via mRNA 3'UTRs to regulate protein expression, and such controls are crucial for development. We show that homozygous mutations in two zebrafish exon junction complex (EJC) core genes rbm8a and magoh lead
Externí odkaz:
https://doaj.org/article/71589bc5dee24425bea29fa9804837ca
Publikováno v:
WIREs RNA. 14
Biological time keeping, or the duration and tempo at which biological processes occur, is a phenomenon that drives dynamic molecular and morphological changes that manifest throughout many facets of life. In some cases, the molecular mechanisms regu
Autor:
Zachary T. Morrow, Nicolas L. Derr, Monica C. Mannings, Thomas L. Gallagher, Kiel T. Tietz, Sharon L. Amacher
Publikováno v:
Dev Biol
Vertebrate segmentation is regulated by the segmentation clock, a biological oscillator that controls periodic formation of somites, or embryonic segments, which give rise to many mesodermal tissue types. This molecular oscillator generates cyclic ge
Autor:
Ralf Bundschuh, Robert D. Patton, Guramrit Singh, Michael A. Parthun, Sharon L. Amacher, Natalie C. Deans, Thomas L. Gallagher, Pooja Gangras, Kiel T. Tietz, Zhongxia Yi
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008830 (2020)
PLoS Genetics
PLoS Genetics
Many post-transcriptional mechanisms operate via mRNA 3′UTRs to regulate protein expression, and such controls are crucial for development. We show that homozygous mutations in two zebrafish exon junction complex (EJC) core genes rbm8a and magoh le
Publikováno v:
Genetics, vol 207, iss 4
Arabidopsis thaliana INNER NO OUTER (INO) is a YABBY protein that is essential for the initiation and development of the outer integument of ovules. Other YABBY proteins have been shown to be involved in both negative and positive regulation of expre
Autor:
Michael A. Berberoglu, Sharon L. Amacher, Kimberly J. Hromowyk, Jared C. Talbot, Thomas L. Gallagher, Inês M. Tenente, David M. Langenau, Zachary T. Morrow
Publikováno v:
Developmental Biology. 424:162-180
Satellite cells, also known as muscle stem cells, are responsible for skeletal muscle growth and repair in mammals. Pax7 and Pax3 transcription factors are established satellite cell markers required for muscle development and regeneration, and there
Autor:
Kiel T. Tietz, Ralf Bundschuh, Robert D. Patton, Pooja Gangras, Parthun Ma, Guramrit Singh, Natalie C. Deans, Thomas L. Gallagher, Sharon L. Amacher, Zhongxia Yi
The Exon Junction Complex (EJC) regulates many steps in post-transcriptional gene expression and is essential for cellular function and organismal development; however, EJC-regulated genes and genetic pathways during development remain largely unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deaf207f212de86627df4d8e4d56ea7f
Autor:
Michael L. Goldrich, Zachary T. Morrow, Nicolas L. Derr, Jasmine M. McCammon, Sharon L. Amacher, Thomas L. Gallagher, Kiel T. Tietz
Publikováno v:
Developmental biology. 429(1)
Vertebrate segmentation is controlled by the segmentation clock, a molecular oscillator that regulates gene expression and cycles rapidly. The expression of many genes oscillates during segmentation, including hairy/Enhancer of split-related ( her or
Autor:
Neha Rastogi, Paul M.L. Janssen, Sharon L. Amacher, Jonathan P. Davis, Christine E. Beattie, Brit L. Martin, Thomas L. Gallagher
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 119(7)
The accessible genetics and extensive skeletal musculature of the zebrafish make it a versatile and increasingly used model for studying muscle contraction. We here describe the development of an in vivo assay for measuring the contractile force of i