Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas L. Flanigan"'
Publikováno v:
Journal of Surgical Research. 156:103-109
Wound healing requires fibroblast migration. Increased pressure slows migration and ulcer healing. Pressure also induces beta1 integrin phosphorylation. We hypothesized that beta1 phosphorylation influences cell adhesion and migration. We compared th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5800aa41b85ccdb29b005dff8e7d8a3d
https://doi.org/10.1016/j.jss.2009.03.053
https://doi.org/10.1016/j.jss.2009.03.053
Autor:
Thomas L. Flanigan, Brittany Alston, Lakshmi S. Chaturvedi, Shouye Wang, Marc D. Basson, Christopher P. Gayer
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 296:G876-G885
Repetitive strain stimulates intestinal epithelial migration across fibronectin via focal adhesion kinase (FAK), Src, and extracellular signal-related kinase (ERK) although how these signals act and interact remains unclear. We hypothesized that PI3K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a1a5a2a0bfd41351130b2a82c7c7f1
https://doi.org/10.1152/ajpgi.90648.2008
https://doi.org/10.1152/ajpgi.90648.2008
Autor:
David H. Craig, Marc D. Basson, Thomas L. Flanigan, Shouye Wang, Lakshmi S. Chaturvedi, Christopher P. Gayer
Publikováno v:
Journal of Biological Chemistry. 284:2001-2011
The intestinal epithelium is repetitively deformed by shear, peristalsis, and villous motility. Such repetitive deformation stimulates the proliferation of intestinal epithelial cells on collagen or laminin substrates via ERK, but the upstream mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044aa07fb2ae8cadcc8cafec0b9e1acd
https://doi.org/10.1074/jbc.m804576200
https://doi.org/10.1074/jbc.m804576200
Autor:
Elizabeth H. Harvey, Michelle R. Young, Thomas L. Flanigan, Arthur M. Carlin, Michael T. White, James G. Tyburski, Donald W. Weaver
Publikováno v:
The American Surgeon. 70:193-197
The Kraske procedure offers a sphincter-saving alternative for surgical correction of rectal disease. This study was performed to investigate the complication rate with the traditional (transsacral) Kraske procedure versus an abdominal-assisted Krask
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52e64075e2d237a4cb76a8c873098a68
https://doi.org/10.1177/000313480407000302
https://doi.org/10.1177/000313480407000302
The influence on mucosal healing of luminal nutrient flow and the forces it creates are poorly understood. We hypothesized that altered deformation and extracellular pressure mediate, in part, the effects of defunctionalization on mucosal healing. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3d470d026179aad62abb7f7c5a059f
https://europepmc.org/articles/PMC3517654/
https://europepmc.org/articles/PMC3517654/
Autor:
Christopher P. Gayer, Dean E. Cress, Marc D. Basson, David H. Craig, Thomas L. Flanigan, Thomas D. Reed
Publikováno v:
Journal of cellular biochemistry. 109(4)
Repetitive deformation like that engendered by peristalsis or villous motility stimulates intestinal epithelial proliferation on collagenous substrates and motility across fibronectin, each requiring ERK. We hypothesized that ERK acts differently at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173615c700596ed9c7e73459245b5aac
https://pubmed.ncbi.nlm.nih.gov/20069571
https://pubmed.ncbi.nlm.nih.gov/20069571
Publikováno v:
American journal of surgery. 196(5)
Background Luminal pressure may injure the gut mucosa in obstruction, ileus, or inflammatory bowel disease. Methods We formed Roux-en-Y anastomoses in 19 mice, creating proximal and defunctionalized partially obstructed limbs and a distal limb to var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bbd8421c026b96699bbf3331c10480
https://pubmed.ncbi.nlm.nih.gov/18954600
https://pubmed.ncbi.nlm.nih.gov/18954600
Autor:
Elizabeth H, Harvey, Michelle R, Young, Thomas L, Flanigan, Arthur M, Carlin, Michael T, White, James G, Tyburski, Donald W, Weaver
Publikováno v:
The American surgeon. 70(3)
The Kraske procedure offers a sphincter-saving alternative for surgical correction of rectal disease. This study was performed to investigate the complication rate with the traditional (transsacral) Kraske procedure versus an abdominal-assisted Krask
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c6a1e8bb26a87dc2468fadc380daaed
https://pubmed.ncbi.nlm.nih.gov/15055840
https://pubmed.ncbi.nlm.nih.gov/15055840
Publikováno v:
Journal of Surgical Research. 151:187
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6f97e5ad0a5d7c94fa27fd8832c743c
https://doi.org/10.1016/j.jss.2008.11.052
https://doi.org/10.1016/j.jss.2008.11.052