Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Thomas L Daniel"'
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 9, p e1010512 (2022)
Insect flight is a strongly nonlinear and actuated dynamical system. As such, strategies for understanding its control have typically relied on either model-based methods or linearizations thereof. Here we develop a framework that combines model pred
Externí odkaz:
https://doaj.org/article/86b3ab7728324802ac8dd1bb5842d9f1
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 8, p e1009195 (2021)
Animals rely on sensory feedback to generate accurate, reliable movements. In many flying insects, strain-sensitive neurons on the wings provide rapid feedback that is critical for stable flight control. While the impacts of wing structure on aerodyn
Externí odkaz:
https://doaj.org/article/eac7378738f0447db67a68538f407c2b
Autor:
Foen Peng, Eric O Campos, Joseph Garret Sullivan, Nathan Berry, Bo Bin Song, Thomas L Daniel, H D Bradshaw
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213029 (2019)
The obligate mutualism and exquisite specificity of many plant-pollinator interactions lead to the expectation that flower phenotypes (e.g., corolla tube length) and corresponding pollinator traits (e.g., hawkmoth proboscis length) are congruent as a
Externí odkaz:
https://doaj.org/article/324878ab8455443cafcc3562e63a37db
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 4, p e1004168 (2015)
What are the features of movement encoded by changing motor commands? Do motor commands encode movement independently or can they be represented in a reduced set of signals (i.e. synergies)? Motor encoding poses a computational and practical challeng
Externí odkaz:
https://doaj.org/article/801e689394c34f459fac7664015ca461
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 5, p e1002506 (2012)
Striated muscle contraction is a highly cooperative process initiated by Ca²⁺ binding to the troponin complex, which leads to tropomyosin movement and myosin cross-bridge (XB) formation along thin filaments. Experimental and computational studies
Externí odkaz:
https://doaj.org/article/85c933d2fc2c426fb2c66329017020c4
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 11, p e1002770 (2012)
We most often consider muscle as a motor generating force in the direction of shortening, but less often consider its roles as a spring or a brake. Here we develop a fully three-dimensional spatially explicit model of muscle to isolate the locations
Externí odkaz:
https://doaj.org/article/35832767c2924f70826fe6fafb5b559b
Autor:
Armin J Hinterwirth, Billie Medina, Jacob Lockey, David Otten, Joel Voldman, Jeffrey H Lang, John G Hildebrand, Thomas L Daniel
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52725 (2012)
Insect antennae are sensory organs involved in a variety of behaviors, sensing many different stimulus modalities. As mechanosensors, they are crucial for flight control in the hawkmoth Manduca sexta. One of their roles is to mediate compensatory ref
Externí odkaz:
https://doaj.org/article/ce92564d8b6f470b9ee3686d942f969d
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 12, p e1001018 (2010)
Nearly all mechanochemical models of the cross-bridge treat myosin as a simple linear spring arranged parallel to the contractile filaments. These single-spring models cannot account for the radial force that muscle generates (orthogonal to the long
Externí odkaz:
https://doaj.org/article/79995336b5fa44129b55e13d1ae12931
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 7, p e115 (2007)
In muscle, force emerges from myosin binding with actin (forming a cross-bridge). This actomyosin binding depends upon myofilament geometry, kinetics of thin-filament Ca(2+) activation, and kinetics of cross-bridge cycling. Binding occurs within a co
Externí odkaz:
https://doaj.org/article/06b24139830944f199fac203c36f119c
Autor:
Hengji Wang, Joshua Swore, Shashank Sharma, John R. Szymanski, Rafael Yuste, Thomas L. Daniel, Michael Regnier, Martha M. Bosma, Adrienne L. Fairhall
Publikováno v:
Proceedings of the National Academy of Sciences. 120
How does neural activity drive muscles to produce behavior? The recent development of genetic lines in Hydra that allow complete calcium imaging of both neuronal and muscle activity, as well as systematic machine learning quantification of behaviors,