Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Thomas L, Rudge"'
1
Akademický článek
Assays for the Evaluation of the Immune Response to Marburg and Ebola Sudan Vaccination—Filovirus Animal Nonclinical Group Anti-Marburg Virus Glycoprotein Immunoglobulin G Enzyme-Linked Immunosorbent Assay and a Pseudovirion Neutralization Assay
Autor: Thomas L. Rudge, Nicholas J. Machesky, Karen A. Sankovich, Erin E. Lemmon, Christopher S. Badorrek, Rachel Overman, Nancy A. Niemuth, Michael S. Anderson
Publikováno v: Vaccines, Vol 10, Iss 8, p 1211 (2022)
Since the discovery of the Marburg virus (MARV) in 1967 and Ebola virus (EBOV) in 1976, there have been over 40 reported outbreaks of filovirus disease with case fatality rates greater than 50%. This underscores the need for efficacious vaccines agai
Externí odkaz: https://doaj.org/article/d4a6d683966d49e69f450f38764f05cb
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2
Akademický článek
Safety and Immunogenicity of a 4-Component Toxoid-Based Staphylococcus aureus Vaccine in Rhesus Macaques
Autor: Arundhathi Venkatasubramaniam, Grant Liao, Eunice Cho, Rajan P. Adhikari, Tom Kort, Frederick W. Holtsberg, Karen E. Elsass, Dean J. Kobs, Thomas L. Rudge, Keith D. Kauffman, Nickiana E. Lora, Daniel L. Barber, M. Javad Aman, Hatice Karauzum
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Staphylococcus aureus is a leading cause of significant morbidity and mortality and an enormous economic burden to public health worldwide. Infections caused by methicillin-resistant S. aureus (MRSA) pose a major threat as MRSA strains are becoming i
Externí odkaz: https://doaj.org/article/c83a2f964899456781ac389d4bee43fb
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3
Akademický článek
Interlaboratory comparison for the Filovirus Animal Nonclinical Group (FANG) anti-Ebola virus glycoprotein immunoglobulin G enzyme-linked immunosorbent assay.
Autor: Michael S Anderson, Nancy A Niemuth, Carol L Sabourin, Christopher S Badorrek, Callie E Bounds, Thomas L Rudge
Publikováno v: PLoS ONE, Vol 15, Iss 8, p e0238196 (2020)
The need for an efficacious vaccine against highly pathogenic filoviruses was reinforced by the devastating 2014-2016 outbreak of Ebola virus (EBOV) disease (EVD) in Guinea, Sierra Leone, and Liberia that resulted in over 28,000 cases and over 11,300
Externí odkaz: https://doaj.org/article/ad669183e1d0412bb45a8896fee14765
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4
Akademický článek
Method feasibility for cross-species testing, qualification, and validation of the Filovirus Animal Nonclinical Group anti-Ebola virus glycoprotein immunoglobulin G enzyme-linked immunosorbent assay for non-human primate serum samples.
Autor: Nancy A Niemuth, Thomas L Rudge, Karen A Sankovich, Michael S Anderson, Nicholas D Skomrock, Christopher S Badorrek, Carol L Sabourin
Publikováno v: PLoS ONE, Vol 15, Iss 10, p e0241016 (2020)
An anti-Zaire Ebola virus (EBOV) glycoprotein (GP) immunoglobulin G (IgG) enzyme linked immunosorbent assay (ELISA) was developed to quantify the serum levels of anti-EBOV IgG in human and non-human primate (NHP) serum following vaccination and/or ex
Externí odkaz: https://doaj.org/article/409e0837db0549c7b44c423e13bf373f
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5
Akademický článek
Development, qualification, and validation of the Filovirus Animal Nonclinical Group anti-Ebola virus glycoprotein immunoglobulin G enzyme-linked immunosorbent assay for human serum samples.
Autor: Thomas L Rudge, Karen A Sankovich, Nancy A Niemuth, Michael S Anderson, Christopher S Badorrek, Nick D Skomrock, Chris M Cirimotich, Carol L Sabourin
Publikováno v: PLoS ONE, Vol 14, Iss 4, p e0215457 (2019)
The need for an efficacious vaccine against highly pathogenic filoviruses was reinforced by the recent and devastating 2014-2016 outbreak of Ebola virus (EBOV) disease in Guinea, Sierra Leone, and Liberia that resulted in more than 10,000 casualties.
Externí odkaz: https://doaj.org/article/f4d526e81a16443ca33df9ab020835db
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6
Mucosal Challenge Ferret Models of Ebola Virus Disease
Autor: Cheryl A. Triplett, Jason E. Comer, Jeanon N. Smith, Trevor Brasel, Melicia Gainey, Nancy A. Niemuth, Shane Massey, Jennifer K. Smith, Andrew Kocsis, Thomas L. Rudge, Matthew Hyde
Publikováno v: Pathogens
Volume 10
Issue 3
Pathogens, Vol 10, Iss 292, p 292 (2021)
Recent studies have shown the domestic ferret (Mustela putorius furo) to be a promising small animal model for the study of Ebola virus (EBOV) disease and medical countermeasure evaluation. To date, most studies have focused on traditional challenge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5f02cbe4f8597059ceef5b6d550e82
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7
Safety and Immunogenicity of a 4-Component Toxoid-Based Staphylococcus aureus Vaccine in Rhesus Macaques
Autor: Rajan P. Adhikari, Dean J. Kobs, Hatice Karauzum, Daniel L. Barber, Eunice Cho, M. Javad Aman, Tom Kort, Grant C. Liao, Keith D. Kauffman, Arundhathi Venkatasubramaniam, Frederick W. Holtsberg, Nickiana E. Lora, Karen E. Elsass, Thomas L. Rudge
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Staphylococcus aureus is a leading cause of significant morbidity and mortality and an enormous economic burden to public health worldwide. Infections caused by methicillin-resistant S. aureus (MRSA) pose a major threat as MRSA strains are becoming i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ab23610f6fad2cc2c0acff751e7989
https://www.frontiersin.org/articles/10.3389/fimmu.2021.621754/full
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8
Interlaboratory comparison for the Filovirus Animal Nonclinical Group (FANG) anti-Ebola virus glycoprotein immunoglobulin G enzyme-linked immunosorbent assay
Autor: Carol L. K. Sabourin, Callie E. Bounds, Thomas L. Rudge, Christopher S. Badorrek, Nancy A. Niemuth, Michael S. Anderson
Publikováno v: PLoS ONE, Vol 15, Iss 8, p e0238196 (2020)
PLoS ONE
The need for an efficacious vaccine against highly pathogenic filoviruses was reinforced by the devastating 2014–2016 outbreak of Ebola virus (EBOV) disease (EVD) in Guinea, Sierra Leone, and Liberia that resulted in over 28,000 cases and over 11,3
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dda856dcb4700d8d6f2801aabed551c
https://doaj.org/article/ad669183e1d0412bb45a8896fee14765
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10
Assessing the safety and immunogenicity of recombinant vesicular stomatitis virus Ebola vaccine in healthy adults: a randomized clinical trial
Autor: W. Jay Ramsey, Donna MacKinnon-Cameron, Catherine Brown, Steven A Kwilas, Scott A. Halperin, D. Gray Heppner, Tracy Kemp, Teresa Nowak, Li Li, Thomas P. Monath, May Elsherif, Jay W. Hooper, Shelly A. McNeil, Carol Sabourin, Christopher S. Badorrek, Trina Racine, Peter Silvera, Thomas L. Rudge, Nicole Kilgore, Judie Alimonti, Joanne M. Langley
Publikováno v: Canadian Medical Association Journal. 189:E819-E827
BACKGROUND: The 2013–2016 Ebola virus outbreak in West Africa was the most widespread in history. In response, alive attenuated recombinant vesicular stomatitis virus (rVSV) vaccine expressing Zaire Ebolavirus glycoprotein (rVSVΔG-ZEBOV-GP) was ev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6497fb1613a605e895f33fc5392b831e
https://doi.org/10.1503/cmaj.170074
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