Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Thomas L, Brown"'
Autor:
Christopher A. Waker, Amy E. Hwang, Scout Bowman-Gibson, Chandni H. Chandiramani, Bryce Linkous, Madison L. Stone, Chanel I. Keoni, Melissa R. Kaufman, Thomas L. Brown
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Preeclampsia is a pregnancy-specific condition and a leading cause of maternal and fetal morbidity and mortality. It is thought to occur due to abnormal placental development or dysfunction, because the only known cure is delivery of the placenta. Se
Externí odkaz:
https://doaj.org/article/da2f506861bd4740bac47468690a572d
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Preeclampsia (PE) is a multisystemic, pregnancy-specific disorder and a leading cause of maternal and fetal death. PE is also associated with an increased risk for chronic morbidities later in life for mother and offspring. Abnormal placentation or p
Externí odkaz:
https://doaj.org/article/3752c3ee4caa4d398957af89c342e97d
Publikováno v:
ImmunoHorizons. 6:334-343
Cardiac resident macrophages facilitate electrical conduction by interacting with cardiomyocytes via connexin-43 (Cx43) hemichannels. Cx43 is critical for impulse propagation and coordination between muscle contractions. Cardiomyocyte electrophysiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b3d086f9d968bf4895c451b3edcf87
https://doi.org/10.4049/immunohorizons.2100104
https://doi.org/10.4049/immunohorizons.2100104
Autor:
William E. Ackerman, Catalin S. Buhimschi, Thomas L. Brown, Guomao Zhao, Taryn L. Summerfield, Irina A. Buhimschi
Background: Placental disorders contribute to pregnancy complications, including preeclampsia and fetal growth restriction (FGR), but debate regarding their specific pathobiology persists. Our objective was to apply transcriptomics with weighted gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b80c09abeb1a0426c0eee6fae9a9070
https://doi.org/10.1101/2023.03.08.23286998
https://doi.org/10.1101/2023.03.08.23286998
Autor:
Peter K. Lauf, Judith Heiny, Jarek Meller, Michael A. Lepera, Leonid Koikov, Gerald M. Alter, Thomas L. Brown, Norma C. Adragna
Publikováno v:
Cellular Physiology and Biochemistry, Vol 31, Iss 2-3, Pp 257-276 (2013)
Background/Aims: Chelerythrine [CET], a protein kinase C [PKC] inhibitor, is a prop-apoptotic BH3-mimetic binding to BH1-like motifs of Bcl-2 proteins. CET action was examined on PKC phosphorylation-dependent membrane transporters (Na+/K+ pump/ATPase
Externí odkaz:
https://doaj.org/article/74150c05f1884e78b6ecb94ad69e4925
Publikováno v:
International Journal of Stem Cells
Background Transforming growth factor beta (TGF-β) signaling has been shown to control a large number of critical cellular actions such as cell death, differentiation, and development and has been implicated as a major regulator of placental functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c58a7cdf203a77b859264a915b9f6f74
https://pubmed.ncbi.nlm.nih.gov/29699384
https://pubmed.ncbi.nlm.nih.gov/29699384
Autor:
Melissa R, Kaufman, Thomas L, Brown
Publikováno v:
Experientia supplementum (2012). 107
AMPK is important in numerous physiological systems but plays a vital role in embryonic and placental development. The placenta is a unique organ that is the essential lifeline between the mother and baby during pregnancy and gestation. During placen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a346460274453a4fb829ef990bec64d
https://pubmed.ncbi.nlm.nih.gov/27812977
https://pubmed.ncbi.nlm.nih.gov/27812977
Autor:
Benjamin Southerland, Kashmira Kulkarni-Datar, Chanel Keoni, Rebecca Bricker, William C. Grunwald, Jr., Daniel M. Ketcha, Eugene Hern, David R. Cool, Thomas L. Brown
Publikováno v:
Journal of Cell Death, Vol 2010, Iss 3, Pp 33-40 (2010)
The broad-spectrum apoptosis (caspase) inhibitor, Q-VD-OPh, has been shown to have no side effects and is effective at a much lower concentration than other FMK-type caspase inhibitors. However, an appropriate negative control to use with this inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::3b2e0abd522973ca4329ab7993174f52
http://la-press.com/q-ve-oph-a-negative-control-for-o-phenoxy-conjugated-caspase-inhibitor-a2089
http://la-press.com/q-ve-oph-a-negative-control-for-o-phenoxy-conjugated-caspase-inhibitor-a2089
Autor:
Christina A, Wicker, Ravi P, Sahu, Kashmira, Kulkarni-Datar, Sanjay K, Srivastava, Thomas L, Brown
Publikováno v:
Cancer growth and metastasis. 2009(2)
Pancreatic adenocarcinoma is an aggressive cancer with a greater than 95% mortality rate and short survival after diagnosis. Chemotherapeutic resistance hinders successful treatment. This resistance is often associated with mutations in codon 12 of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d008d94862f650b6b554b00c36ad3ad
https://pubmed.ncbi.nlm.nih.gov/20559452
https://pubmed.ncbi.nlm.nih.gov/20559452