Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Thomas Krusenstjerna- Hafstrøm"'
Publikováno v:
BMC Pediatrics, Vol 20, Iss 1, Pp 1-6 (2020)
Abstract Background A high number of children are referred to pediatric departments with a suspected allergic reaction to antibiotics. The prevalence of true allergy is considered to be significantly lower than shown from clinical history and symptom
Externí odkaz:
https://doaj.org/article/df5e029be0b74e0f9d38405ea07b6285
Autor:
Mai C Arlien-Søborg, Michael Alle Madsen, Jakob Dal, Thomas Krusenstjerna-Hafstrøm, Steffen Ringgaard, Nickolaj Skou, Morten Høgild, Jens Otto Lunde Jørgensen
Publikováno v:
Arlien-Søborg, M C, Madsen, M A, Dal, J, Krusenstjerna-Hafstrøm, T, Ringgaard, S, Skou, N, Høgild, M & Jørgensen, J O L 2023, ' Ectopic lipid deposition and insulin resistance in patients with GH disorders before and after treatment ', European Journal of Endocrinology, vol. 188, no. 1, lvac014 . https://doi.org/10.1093/ejendo/lvac014
Arlien-Søborg, M C, Madsen, M A, Dal, J, Krusenstjerna-Hafstrøm, T, Ringgaard, S, Skou, N, Høgild, M & Jørgensen, J O L 2023, ' Ectopic lipid deposition and insulin resistance in patients with GH disorders before and after treatment ', European Journal of Endocrinology, vol. 188, no. 1 . https://doi.org/10.1093/ejendo/lvac014
Arlien-Søborg, M C, Madsen, M A, Dal, J, Krusenstjerna-Hafstrøm, T, Ringgaard, S, Skou, N, Høgild, M & Jørgensen, J O L 2023, ' Ectopic lipid deposition and insulin resistance in patients with GH disorders before and after treatment ', European Journal of Endocrinology, vol. 188, no. 1 . https://doi.org/10.1093/ejendo/lvac014
Objectives Insulin resistance is associated with ectopic lipid deposition. Growth hormone (GH) status also modulates ectopic lipid accumulation, but how this associates with insulin resistance in patients with GH disorders is not well established. De
Publikováno v:
BMC Pediatrics, Vol 20, Iss 1, Pp 1-6 (2020)
Krusenstjerna-Hafstrøm, T & Rubak, S 2020, ' The use of direct oral challenge to confirm allergies to penicillin class antibiotics in Danish children ', BMC Pediatrics, vol. 20, 523 . https://doi.org/10.1186/s12887-020-02407-z
BMC Pediatrics
Krusenstjerna-Hafstrøm, T & Rubak, S 2020, ' The use of direct oral challenge to confirm allergies to penicillin class antibiotics in Danish children ', BMC Pediatrics, vol. 20, 523 . https://doi.org/10.1186/s12887-020-02407-z
BMC Pediatrics
Background A high number of children are referred to pediatric departments with a suspected allergic reaction to antibiotics. The prevalence of true allergy is considered to be significantly lower than shown from clinical history and symptoms alone.
Autor:
Thomas Krusenstjerna-Hafstrøm, Michael Madsen, Mikkel H Vendelbo, Steen B Pedersen, Jens S Christiansen, Niels Møller, Niels Jessen, Jens O L Jørgensen
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19392 (2011)
GH induces acute insulin resistance in skeletal muscle in vivo, which in rodent models has been attributed to crosstalk between GH and insulin signaling pathways. Our objective was to characterize time course changes in signaling pathways for GH and
Externí odkaz:
https://doaj.org/article/0b1827b1481e4c6cb3dfce6f21da90d7
Autor:
Jan Frystyk, Niels Jessen, Troels Krarup Hansen, Hans Stødkilde-Jørgensen, Louise Møller, Thomas Krusenstjerna-Hafstrøm, Allan Flyvbjerg, Britt Christensen, Jens Otto Lunde Jørgensen, Michael Madsen, Mikkel H. Vendelbo, Steen B. Pedersen
Publikováno v:
Madsen, M, Hafstrøm, T K, Møller, L, Christensen, B, Vendelbo, M H, Pedersen, S B, Frystyk, J, Jessen, N, Hansen, T K, Stødkilde-Jørgensen, H, Flyvbjerg, A & Jørgensen, J O L 2012, ' Fat Content in Liver and Skeletal Muscle Changes in a Reciprocal Manner in Patients with Acromegaly during Combination Therapy with a Somatostatin Analog and a GH Receptor Antagonist : A Randomized Clinical Trial ', Journal of Clinical Endocrinology and Metabolism . https://doi.org/10.1210/jc.2011-2681
Context: Pegvisomant is a GH antagonist, which is used for the treatment of acromegalic patients. It effectively blocks the hepatic and peripheral effects of GH, but transient elevations in circulating liver enzymes of unknown pathogenesis may occur,
Autor:
Niels Jessen, Jens Otto Lunde Jørgensen, Niels Møller, Laurie J. Goodyear, Mikkel H. Vendelbo, Jonas T. Treebak, Mogens Rørbæk Madsen, Berthil F. Clasen, Louise Møller, Thomas Krusenstjerna-Hafstrøm, Steen B. Pedersen, Jørgen F. P. Wojtaszewski, Hans Stødkilde-Jørgensen, Thomas Nielsen
Publikováno v:
Vendelbo, M H, Clasen, B F F, Treebak, J T, Møller, L, Krusenstjerna-Hafstrøm, T, Madsen, M, Nielsen, T S, Stødkilde-Jørgensen, H, Pedersen, S B, Jørgensen, J O L, Goodyear, L J, Wojtaszewski, J F P, Møller, N & Jessen, N 2012, ' Insulin Resistance after a 72 hour Fast is Associated with Impaired AS160 Phosphorylation and Accumulation of Lipid and Glycogen in Human Skeletal Muscle ', American Journal of Physiology: Endocrinology and Metabolism, vol. 95, no. 2, pp. 283-289 . https://doi.org/10.1152/ajpendo.00207.2011
During fasting, human skeletal muscle depends on lipid oxidation for its energy substrate metabolism. This is associated with the development of insulin resistance and a subsequent reduction of insulin-stimulated glucose uptake. The underlying mechan
Autor:
Thomas Krusenstjerna-Hafstrøm, Michael J. Raschke, Shunmugam Govender, Jens Sandahl Christiansen, Michael Højby Rasmussen, Jesper J. Madsen
Publikováno v:
Growth Hormone & IGF Research. 21:331-335
Context It has been argued that increased levels of bone remodelling markers are not suitable indicators of GH abuse, as bone injuries per se increase the expression levels of these markers. Objective To investigate the impact of a recovering tibia f
Autor:
Steen B. Pedersen, Niels Jessen, Niels Møller, Thomas Krusenstjerna-Hafstrøm, Carlos Escande, Kasper Thorsen, Mikkel H. Vendelbo, Jens Otto Lunde Jørgensen, Berthil F. Clasen
Publikováno v:
Clasen, B F F, Hafstrøm, T K, Vendelbo, M H, Thorsen, K, Escande, C, Moller, N, Pedersen, S B, Jørgensen, J O L & Jessen, N 2013, ' Gene Expression in Skeletal Muscle after an Acute Intravenous GH Bolus in Human Subjects: Identification of a Mechanism Regulating ANGPTL4 ', Journal of Lipid Research, vol. 54, no. 7, pp. 1988-1997 . https://doi.org/10.1194/jlr.P034520
Journal of Lipid Research, Vol 54, Iss 7, Pp 1988-1997 (2013)
Journal of Lipid Research, Vol 54, Iss 7, Pp 1988-1997 (2013)
Growth hormone (GH) acutely stimulates lipolysis and fat oxidation, a process which operates postabsorptively and involves activation of the JAK-STAT pathway in the target tissue; no in vivo data exist regarding subsequent GH-regulated gene transcrip
Autor:
Niels Jessen, Britt Christensen, Mikkel H. Vendelbo, Michael Madsen, Niels Møller, Steen B. Pedersen, Thomas Krusenstjerna-Hafstrøm, Jens Otto Lunde Jørgensen
Publikováno v:
Christensen, B, Vendelbo, M H, Hafstrøm, T K, Madsen, M, Pedersen, S B, Jessen, N, Møller, N & Jørgensen, J O L 2012, ' Erythropoietin administration acutely stimulates resting energy expenditure in healthy young men ', Journal of Applied Physiology, vol. 112, no. 7, pp. 1114-21 . https://doi.org/10.1152/japplphysiol.01391.2011
Treatment with recombinant human erythropoietin (rHuEpo) improves insulin sensitivity in patients with end-stage renal disease, and animal studies indicate that Epo increases fat oxidation. However, the metabolic effects of rHuEpo have never been exp
Autor:
Niels Møller, Jens Otto Lunde Jørgensen, Niels Jessen, Berthil F. Clasen, Jørgen S. Christiansen, Thomas Krusenstjerna-Hafstrøm, Steen B. Pedersen
Publikováno v:
Krusenstjerna-Hafstrøm, T, Clasen, B F, Møller, N, Jessen, N, Pedersen, SB, Christiansen, J S & Jørgensen, J O L 2011, ' Growth hormone (GH)-induced insulin resistance is rapidly reversible: an experimental study in GH-deficient adults ', Journal of Clinical Endocrinology and Metabolism, vol. 96, no. 8, pp. 2548-57 . https://doi.org/10.1210/jc.2011-0273
It is clinically relevant and of physiological interest to investigate whether GH-induced insulin resistance depends on the timing of GH exposure relative to when insulin sensitivity is assessed.GH-induced insulin resistance is rapidly reversible.Eig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6f0c9bc63d3b9af7afc8d326ed62d6
https://pure.au.dk/portal/da/publications/growth-hormone-ghinduced-insulin-resistance-is-rapidly-reversible-an-experimental-study-in-ghdeficient-adults(25b4d8e8-9d96-43d9-a4d5-ac891622f263).html
https://pure.au.dk/portal/da/publications/growth-hormone-ghinduced-insulin-resistance-is-rapidly-reversible-an-experimental-study-in-ghdeficient-adults(25b4d8e8-9d96-43d9-a4d5-ac891622f263).html