Zobrazeno 1 - 10
of 336
pro vyhledávání: '"Thomas Kissel"'
Publikováno v:
Polymers, Vol 3, Iss 2, Pp 693-718 (2011)
The aim of this study was to investigate non-viral pDNA carriers based on diblock-copolymers consisting of poly(2-(dimethyl amino)ethyl methacrylate) (pDMAEMA) and poly(2-hydroxyethyl methacrylate) (pHEMA). Specifically the block-lengths and molecula
Externí odkaz:
https://doaj.org/article/81f3f76272ad4e6097e1e71faa1291ac
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 11, Iss 1, Pp 64-65 (2016)
Externí odkaz:
https://doaj.org/article/5e11295a14cd497cb3fc3a98c180fee1
Autor:
Daniel Hänggi, Jason Perrin, Sven Eicker, Kerim Beseoglu, Nima Etminan, Marcel Alexander Kamp, Hi-Jae Heiroth, Nadia Bege, Stephan Macht, Katrin Frauenknecht, Clemens Sommer, Thomas Kissel, Hans-Jakob Steiger
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e42597 (2012)
Background and purposeTo investigate the effect of locally applied nimodipine prolonged-release microparticles on angiographic vasospasm and secondary brain injury after experimental subarachnoid hemorrhage (SAH).Methods70 male Wistar rats were categ
Externí odkaz:
https://doaj.org/article/f7a63de9084141b09ad1a8690d99bbde
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1943
Pulmonary siRNA delivery has attracted strong interest and has been reported to successfully mediate target gene knockdown in a number of disease models. However, the nature of the epithelial cells that eventually take up siRNA and the question if ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40c6d4840d2fb17e9748b0c8583ee4a1
https://pubmed.ncbi.nlm.nih.gov/30838629
https://pubmed.ncbi.nlm.nih.gov/30838629
Autor:
Thomas Kissel, Juliane Nguyen, Werner Seeger, Moritz Beck-Broichsitter, Olga Samsonova, Thomas Schmehl
Publikováno v:
European Journal of Pharmaceutical Sciences. 86:34-40
A suitable aerosol droplet size and formulation output rate is essential for the therapy of lung diseases under application of nebulizers. The current study investigated the potential of amine-modified poly(vinyl alcohol)s as excipients for inhalatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59356c14043e68e38889686f59b78088
https://doi.org/10.1016/j.ejps.2016.02.023
https://doi.org/10.1016/j.ejps.2016.02.023
Autor:
Ralph T. Schermuly, Moritz Beck-Broichsitter, Werner Seeger, Thomas Kissel, Djuro Kosanovic, Hossein Ardeschir Ghofrani, Thomas Schmehl, Andreas Hecker, Tobias Gessler, Norbert Weissmann
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 12:63-68
Direct vasodilator delivery to the airways enables a selective therapy of pulmonary hypertension (PH). However, short-term effects of the applied medication require multiple daily inhalations. Controlled release formulations (polymeric nanomedicines)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6be749a7a9f35e912c87614ad7d0f2
https://doi.org/10.1016/j.nano.2015.08.009
https://doi.org/10.1016/j.nano.2015.08.009
Publikováno v:
Molecular Pharmaceutics. 13:134-143
Efficient delivery of functional nucleic acids into specific cells or tissues is still a challenge for gene therapy and largely depends on targeted delivery strategies. The folate receptor (FR) is known to be overexpressed extracellularly on a variet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63953e307f10177bd16ac687a49356ef
https://doi.org/10.1021/acs.molpharmaceut.5b00575
https://doi.org/10.1021/acs.molpharmaceut.5b00575
Publikováno v:
Powder Technology. 286:311-317
The current study describes a convenient method for a direct size classification of spray-dried powders, which is of general interest for diverse applications in drug delivery. Accordingly, the time-consuming “trial-and-error” approach to identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec2f756e5cf55201bc0f77427fe9086d
https://doi.org/10.1016/j.powtec.2015.08.033
https://doi.org/10.1016/j.powtec.2015.08.033
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 92:96-101
This work describes uniform polymer coatings allowing for an adjustment of the orifice dimension of vibrating-mesh nozzles and therefore, size of emerging formulation droplets and dried particles, which is of general interest for diverse spray-drying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8054c3b54288b6f9d9a24adacdfa4014
https://doi.org/10.1016/j.ejpb.2015.03.001
https://doi.org/10.1016/j.ejpb.2015.03.001