Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Thomas Kerzel"'
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103196- (2024)
Summary: VisualZoneR is an R-based technique used to analyze spatial transcriptomics data generated by employing Visium or Visium HD technology. Here, we present a protocol to identify compartmental zones from single-cell spatial transcriptomics usin
Externí odkaz:
https://doaj.org/article/b1d01103bbff4361b703a1361c853c16
Autor:
Kaveri Banerjee, Thomas Kerzel, Tove Bekkhus, Sabrina de Souza Ferreira, Tatjana Wallmann, Majken Wallerius, Laura-Sophie Landwehr, Dennis Alexander Agardy, Nele Schauer, Anna Malmerfeldt, Jonas Bergh, Margarita Bartish, Johan Hartman, Arne Östman, Mario Leonardo Squadrito, Charlotte Rolny
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113507- (2023)
Summary: The expression of pro-lymphangiogenic VEGF-C in primary tumors is associated with sentinel lymph node metastasis in most solid cancer types. However, the impact of VEGF-C on distant organ metastasis remains unclear. Perivascular tumor-associ
Externí odkaz:
https://doaj.org/article/15e2b38c40204132ac19ff3affd3486f
Autor:
Laura Kapitza, Naphang Ho, Thomas Kerzel, Annika M. Frank, Frederic B. Thalheimer, Arezoo Jamali, Thomas Schaser, Christian J. Buchholz, Jessica Hartmann
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Chimeric antigen receptor (CAR)-expressing T cells are a complex and heterogeneous gene therapy product with variable phenotype compositions. A higher proportion of less differentiated CAR T cells is usually associated with improved antitumoral funct
Externí odkaz:
https://doaj.org/article/d16778f7ed9243059db65c4e58de6741
Autor:
Monica Soldi, Lucia Sergi Sergi, Giulia Unali, Thomas Kerzel, Ivan Cuccovillo, Paola Capasso, Andrea Annoni, Mauro Biffi, Paola Maria Vittoria Rancoita, Alessio Cantore, Angelo Lombardo, Luigi Naldini, Mario Leonardo Squadrito, Anna Kajaste-Rudnitski
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 411-425 (2020)
Lentiviral vectors (LVs) are increasingly employed in gene and cell therapy. Standard laboratory production of LVs is not easily scalable, and research-grade LVs often contain contaminants that can interfere with downstream applications. Moreover, pu
Externí odkaz:
https://doaj.org/article/e9a98b4f0c0f4908aaf5513efa10181b
Autor:
Sabrina de Souza Ferreira, Tatjana Wallmann, Thomas Kerzel, Majken Wallerius, Nele Schauer, Laura-Sophie Landwehr, Dennis Alexander Agardy, Jonas Bergh, Margarita Bartish, Johan Hartman, Mario Leonardo Squadrito, Charlotte Rolny
Publikováno v:
SSRN Electronic Journal.
Autor:
Laura Kapitza, Naphang Ho, Thomas Kerzel, Annika Frank M, Frederic Thalheimer B, Thomas Schaser, Christian Buchholz, Jessica Hartmann
Chimeric antigen receptor (CAR) expressing T cells are a complex and heterogeneous gene therapy product with variable phenotype composition. A higher proportion of less differentiated CAR T cells is usually associated with improved antitumoral functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d10f91e3a83a0876984f00f4b71f1a4
https://doi.org/10.22541/au.166429989.90389382/v1
https://doi.org/10.22541/au.166429989.90389382/v1
Autor:
Alessio Cantore, Monica Soldi, Lucia Sergi Sergi, Thomas Kerzel, Anna Kajaste-Rudnitski, Paola Capasso, Luigi Naldini, Mario Leonardo Squadrito, Andrea Annoni, Ivan Cuccovillo, Giulia Unali, Mauro Biffi, Paola M.V. Rancoita, Angelo Lombardo
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 411-425 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy-Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Molecular Therapy-Methods & Clinical Development
Lentiviral vectors (LVs) are increasingly employed in gene and cell therapy. Standard laboratory production of LVs is not easily scalable, and research-grade LVs often contain contaminants that can interfere with downstream applications. Moreover, pu
Autor:
Sabrina de Souza Ferreira, Tatjana Wallmann, Thomas Kerzel, Majken Wallerius, Nele Schauer, Laura-Sophie Landwehr, Dennis Alexander Agardy, Jonas Bergh, Margarita Bartish, Johan Hartman, Mario Leonardo Squadrito, Charlotte Rolny
Expression of pro-lymphangiogenic vascular endothelial growth factor C (VEGF-C) in primary tumors correlates with the occurrence of proximal lymph node metastasis in most solid cancer types. However, the role of VEGF-C in regulating tumor cell dissem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67cff062ae5d88a7720de92b2bc0dae3
https://doi.org/10.1101/2022.01.26.468593
https://doi.org/10.1101/2022.01.26.468593
Autor:
Thomas Kerzel, Stefano Beretta, Eloise Scamardella, Chiara Balestrieri, Tamara Canu, Federica Pedica, Rossana Norata, Lucia Sergi Sergi, Marco Genua, Ostuni Renato, Anna Kajaste-Rudnitski, Antonio Esposito, Masanobu Oshima, Giovanni Tonon, Francesca Sanvito, Mario Leonardo Squadrito, Luigi Naldini
Publikováno v:
Cancer Research. 82:3297-3297
The liver hosts an immune suppressive environment favouring metastatic seeding and proliferation of cancer cells. Pharmacological treatments, including immunotherapies, fail in the presence of liver metastases (LMS). Therefore, identifying new interv
Autor:
Anne Laure Joly, Christina Seitz, Samuel E.J. Preston, Majken Wallerius, Talin Ebrahimian, Stephanie Lehoux, Sonia V. del Rincón, Jonas Bergh, Ola Larsson, Johannes Ristau, Kristian Pietras, Laia Masvidal, Yangxun Pan, John Andersson, Mario Leonardo Squadrito, Christophe Goncalves, Luigi Naldini, Tatjana Wallmann, Hui Liu, Thomas Kerzel, Margarita Bartish, Sabrina de Souza Ferreira, Dongmei Tong, Charlotte Rolny, Vincent van Hoef
Publikováno v:
Proc Natl Acad Sci U S A
Tumor-associated macrophages (TAMs) continuously fine tune their immune modulatory properties, but how gene expression programs coordinate this immune cell plasticity is largely unknown. Selective mRNA translation, controlled by MNK1/MNK2 and mTOR pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1704cb457e1d097f850f59c19770dc73